Publications by authors named "Karl Rodriguez"

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Developing Topics.
Andrew Pickering, Maria Gaczynska, Pawel Osmulski, Karl Rodriguez

Alzheimers Dement· December 2025

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A novel endoplasmic reticulum adaptation is critical for the long-lived Caenorhabditis elegans rpn-10 proteasomal mutant.
Meghna N Chinchankar, William B Taylor, Su-Hyuk Ko, Ellen C Apple, Karl A Rodriguez

Biochim Biophys Acta Gene Regul Mech· September 2023

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Correction to: Pterocarpus marsupium extract extends replicative lifespan in budding yeast.
Mitchell B Lee, Michael G Kiflezghi, Mitsuhiro Tsuchiya, Brian Wasko, Daniel T Carr, Karl Rodriguez

Geroscience· June 2022

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HspB1 Overexpression Improves Life Span and Stress Resistance in an Invertebrate Model.
Courtney Carroll Alexander, Erin Munkáscy, Haven Tillmon, Tamara Fraker, Jessica Scheirer, Karl A Rodriguez

J Gerontol A Biol Sci Med Sci· February 2022

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Pterocarpus marsupium extract extends replicative lifespan in budding yeast.
Mitchell B Lee, Michael G Kiflezghi, Mitsuhiro Tsuchiya, Brian Wasko, Daniel T Carr, Karl Rodriguez

Geroscience· October 2021

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Superoxide-mediated oxidative stress accelerates skeletal muscle atrophy by synchronous activation of proteolytic systems.
Young C Jang, Karl Rodriguez, Michael S Lustgarten, Florian L Muller, Arunabh Bhattacharya

Geroscience· December 2020

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Mechanisms regulating proteostasis are involved in sympatric speciation of the blind mole rat, Spalax galili.
Karl A Rodriguez, Kexin Li, Eviatar Nevo, Rochelle Buffenstein

Autophagy· December 2016

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Oxidative damage to myelin proteins accompanies peripheral nerve motor dysfunction in aging C57BL/6 male mice.
Ryan Hamilton, Michael Walsh, Rashmi Singh, Karl Rodriguez, Xiaoli Gao

J Neurol Sci· November 2016

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Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat.
Judy C Triplett, Aaron M Swomley, Jessime Kirk, Kelly M Grimes, Kaitilyn N Lewis, Karl A Rodriguez

Neurochem Res· July 2016

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Determinants of rodent longevity in the chaperone-protein degradation network.
Karl A Rodriguez, Joseph M Valentine, David A Kramer, Jonathan A Gelfond, Deborah M Kristan

Cell Stress Chaperones· May 2016

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Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity.
Judy C Triplett, Antonella Tramutola, Aaron Swomley, Jessime Kirk, Kelly Grimes, Karl Rodriguez

Biochim Biophys Acta· October 2015

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Sympatric speciation revealed by genome-wide divergence in the blind mole rat Spalax.
Kexin Li, Wei Hong, Hengwu Jiao, Guo-Dong Wang, Karl A Rodriguez

Proc Natl Acad Sci U S A· September 2015

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Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.
Judy C Triplett, Aaron Swomley, Jessime Kirk, Katilyn Lewis, Miranda Orr, Karl Rodriguez

J Neurochem· August 2015

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Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates.
Valentina R Garbarino, Miranda E Orr, Karl A Rodriguez, Rochelle Buffenstein

Arch Biochem Biophys· June 2015

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A cytosolic protein factor from the naked mole-rat activates proteasomes of other species and protects these from inhibition.
Karl A Rodriguez, Pawel A Osmulski, Anson Pierce, Susan T Weintraub, Maria Gaczynska

Biochim Biophys Acta· November 2014

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Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice.
Karl A Rodriguez, Sherry G Dodds, Randy Strong, Veronica Galvan, Z D Sharp

Front Mol Neurosci· November 2014

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Elevated protein carbonylation, and misfolding in sciatic nerve from db/db and Sod1(-/-) mice: plausible link between oxidative stress and demyelination.
Ryan T Hamilton, Arunabh Bhattacharya, Michael E Walsh, Yun Shi, Rochelle Wei, Karl A Rodriguez

PLoS One· September 2014

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Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat.
Karl A Rodriguez, Yael H Edrey, Pawel Osmulski, Maria Gaczynska, Rochelle Buffenstein

PLoS One· September 2012

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Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent.
Karl A Rodriguez, Ewa Wywial, Viviana I Perez, Adriant J Lambert, Yael H Edrey

Curr Pharm Des· May 2012

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Molecular mechanisms of proteasome plasticity in aging.
Karl A Rodriguez, Maria Gaczynska, Pawel A Osmulski

Mech Ageing Dev· February 2010

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Increased cell-to-cell variation in gene expression in ageing mouse heart.
Rumana Bahar, Claudia H Hartmann, Karl A Rodriguez, Ashley D Denny, Rita A Busuttil

Nature· June 2006

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Highbrow proteasome in high-throughput technology.
Maria Gaczynska, Karl Rodriguez, Srividya Madabhushi, Pawel A Osmulski

Expert Rev Proteomics· February 2006

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The genome factor in region-specific DNA damage: the DNA-reactive drug U-78779 prefers mixed A/T-G/C sequences at the nucleotide level but is region-specific for long pure AT islands at the genomic level.
Maryanne C S Herzig, Karl A Rodriguez, Alex V Trevino, Jaroslaw Dziegielewski, Brenda Arnett

Biochemistry· February 2002

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