Publications by authors named "Karnail Atwal"

Claim this Profile
T
Triazolo and imidazo dihydropyrazolopyrimidine potassium channel antagonists.
Heather J Finlay, Ji Jiang, Yolanda Caringal, Alexander Kover, Mary Lee Conder, Karnail Atwal

Bioorg Med Chem Lett· March 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of ((S)-5-(methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone as a potent and selective I(Kur) inhibitor.
Heather J Finlay, John Lloyd, Wayne Vaccaro, Alexander Kover, Lin Yan, Karnail Atwal

J Med Chem· April 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors.
Yan Shi, Stephen P O'Connor, Doree Sitkoff, Jing Zhang, Mengxiao Shi, Karnail S Atwal

Bioorg Med Chem Lett· December 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Triphenylphosphine oxide is a potent and selective inhibitor of the transient receptor potential melastatin-5 ion channel.
R Kyle Palmer, Karnail Atwal, Ivona Bakaj, Stacy Carlucci-Derbyshire, M Tulu Buber

Assay Drug Dev Technol· December 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pyrrolidine amides of pyrazolodihydropyrimidines as potent and selective KV1.5 blockers.
John Lloyd, Heather J Finlay, Wayne Vacarro, Tram Hyunh, Alexander Kover, Karnail Atwal

Bioorg Med Chem Lett· February 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577.
Yan Shi, Chi Li, Stephen P O'Connor, Jing Zhang, Mengxiao Shi, Karnail S Atwal

Bioorg Med Chem Lett· December 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dihydropyrazolopyrimidines containing benzimidazoles as K(V)1.5 potassium channel antagonists.
John Lloyd, Heather J Finlay, Karnail Atwal, Alexander Kover, Joseph Prol

Bioorg Med Chem Lett· September 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors.
Yan Shi, Jing Zhang, Mengxiao Shi, Stephen P O'Connor, Sharon N Bisaha, Karnail S Atwal

Bioorg Med Chem Lett· August 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design, structure-activity relationships, X-ray crystal structure, and energetic contributions of a critical P1 pharmacophore: 3-chloroindole-7-yl-based factor Xa inhibitors.
Yan Shi, Doree Sitkoff, Jing Zhang, Herbert E Klei, Kevin Kish, Karnail S Atwal

J Med Chem· December 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dihydropyrazolopyrimidine inhibitors of K(V)1.5 (I(Kur)).
Wayne Vaccaro, Tram Huynh, John Lloyd, Karnail Atwal, Heather J Finlay

Bioorg Med Chem Lett· December 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and evaluation of acylguanidine FXa inhibitors.
Stephen P O'Connor, Karnail Atwal, Chi Li, Eddie C-K Liu, Steven M Seiler

Bioorg Med Chem Lett· August 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pyrano-[2,3b]-pyridines as potassium channel antagonists.
Heather J Finlay, John Lloyd, Michael Nyman, Mary Lee Conder, Tonya West, Karnail Atwal

Bioorg Med Chem Lett· April 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Potent non-nitrile dipeptidic dipeptidyl peptidase IV inhibitors.
Ligaya M Simpkins, Scott Bolton, Zulan Pi, James C Sutton, Chet Kwon, Karnail S Atwal

Bioorg Med Chem Lett· December 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Amino(methyl) pyrrolidines as novel scaffolds for factor Xa inhibitors.
Yan Shi, Doree Sitkoff, Jing Zhang, Wei Han, Zilun Hu, Karnail S Atwal

Bioorg Med Chem Lett· November 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Benzopyran sulfonamides as KV1.5 potassium channel blockers.
John Lloyd, Karnail S Atwal, Heather J Finlay, Michael Nyman, Tram Huynh

Bioorg Med Chem Lett· June 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and biological activity of 5-aryl-4-(4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl)pyrimidine analogs as potent, highly selective, and orally bioavailable NHE-1 inhibitors.
Karnail S Atwal, Steven V O'Neil, Saleem Ahmad, Lidia Doweyko, Mark Kirby

Bioorg Med Chem Lett· September 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
K
Ketene aminal-based lactam derivatives as a novel class of orally active FXa inhibitors.
Yan Shi, Jing Zhang, Philip D Stein, Mengxiao Shi, Stephen P O'Connor, Karnail S Atwal

Bioorg Med Chem Lett· December 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase.
David S Weinstein, Wen Liu, Zhengxiang Gu, Charles Langevine, Khehyong Ngu, Karnail S Atwal

Bioorg Med Chem Lett· March 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Excessive ATP hydrolysis in ischemic myocardium by mitochondrial F1F0-ATPase: effect of selective pharmacological inhibition of mitochondrial ATPase hydrolase activity.
Gary J Grover, Karnail S Atwal, Paul G Sleph, Feng-Li Wang, Hossain Monshizadegan

Am J Physiol Heart Circ Physiol· October 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Small molecule mitochondrial F1F0 ATPase hydrolase inhibitors as cardioprotective agents. Identification of 4-(N-arylimidazole)-substituted benzopyran derivatives as selective hydrolase inhibitors.
Karnail S Atwal, Paulina Wang, W Lynn Rogers, Paul Sleph, Hossain Monshizadegan

J Med Chem· February 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
N-[1-Aryl-2-(1-imidazolo)ethyl]-guanidine derivatives as potent inhibitors of the bovine mitochondrial F1F0 ATP hydrolase.
Karnail S Atwal, Saleem Ahmad, Charles Z Ding, Philip D Stein, John Lloyd

Bioorg Med Chem Lett· February 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Benzodiazepine-based selective inhibitors of mitochondrial F1F0 ATP hydrolase.
Lawrence G Hamann, Charles Z Ding, Arthur V Miller, Cort S Madsen, Paulina Wang, Karnail S Atwal

Bioorg Med Chem Lett· February 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Tetrahydronaphthalene-derived amino alcohols and amino ketones as potent and selective inhibitors of the delayed rectifier potassium current IKs.
Saleem Ahmad, Lidia Doweyko, Aaila Ashfaq, Francis N Ferrara, Sharon N Bisaha, Karnail S Atwal

Bioorg Med Chem Lett· January 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Aminoimidazoles as bioisosteres of acylguanidines: novel, potent, selective and orally bioavailable inhibitors of the sodium hydrogen exchanger isoform-1.
Saleem Ahmad, Khehyong Ngu, Donald W Combs, Shung C Wu, David S Weinstein, Karnail S Atwal

Bioorg Med Chem Lett· January 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
One-pot synthesis and conformational features of n,n'-disubstituted ketene aminals.
Yan Shi, Jing Zhang, Nyeemah Grazier, Philip D Stein, Karnail S Atwal

J Org Chem· January 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis