Publications by authors named "Steven M Seiler"

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Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold.
Scott A Bolton, James C Sutton, Rushith Anumula, Gregory S Bisacchi, Bruce Jacobson, Steven M Seiler

Bioorg Med Chem Lett· September 2013

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Synthesis and evaluation of acylguanidine FXa inhibitors.
Stephen P O'Connor, Karnail Atwal, Chi Li, Eddie C-K Liu, Steven M Seiler

Bioorg Med Chem Lett· August 2008

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Ketene aminal-based lactam derivatives as a novel class of orally active FXa inhibitors.
Yan Shi, Jing Zhang, Philip D Stein, Mengxiao Shi, Stephen P O'Connor, Steven M Seiler

Bioorg Med Chem Lett· December 2005

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Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase.
Gregory S Bisacchi, William A Slusarchyk, Scott A Bolton, Karen S Hartl, Glenn Jacobs, Steven M Seiler

Bioorg Med Chem Lett· May 2004

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Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors.
James C Sutton, Scott A Bolton, Malcolm E Davis, Karen S Hartl, Bruce Jacobson, Steven M Seiler

Bioorg Med Chem Lett· May 2004

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Synthesis of potent and selective 2-azepanone inhibitors of human tryptase.
Guohua Zhao, Scott A Bolton, Chet Kwon, Karen S Hartl, Steven M Seiler

Bioorg Med Chem Lett· January 2004

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Peptide-derived protease-activated receptor-1 (PAR-1) antagonists.
Steven M Seiler, Michael S Bernatowicz

Curr Med Chem Cardiovasc Hematol Agents· March 2003

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Retro-binding thrombin active site inhibitors: identification of an orally active inhibitor of thrombin catalytic activity.
Edwin J Iwanowicz, S David Kimball, James Lin, Wan Lau, W-C Han, Steven M Seiler

Bioorg Med Chem Lett· November 2002

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Synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors.
James C Sutton, Scott A Bolton, Karen S Hartl, Ming-Hsing Huang, Glenn Jacobs, Steven M Seiler

Bioorg Med Chem Lett· November 2002

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Synthesis of potent and highly selective inhibitors of human tryptase.
William A Slusarchyk, Scott A Bolton, Karen S Hartl, Ming-Hsing Huang, Glenn Jacobs, Steven M Seiler

Bioorg Med Chem Lett· November 2002

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Thrombin active site inhibitors: chemical synthesis, in vitro and in vivo pharmacological profile of a novel and selective agent BMS-189090 and analogues.
Jagabandhu Das, S David Kimball, Joyce A Reid, Tammy C Wang, Wan F Lau, Steven M Seiler

Bioorg Med Chem Lett· January 2002

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Molecular design and structure--activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664.
Jagabandhu Das, S David Kimball, Steven E Hall, Wen Ching Han, Edwin Iwanowicz, Steven M Seiler

Bioorg Med Chem Lett· January 2002

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