Publications by authors named "Kate Blease"

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Correction to "Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005".
Patrick Papa, Brandon Whitefield, Deborah S Mortensen, Dan Cashion, Dehua Huang, Kate Blease

J Med Chem· December 2024

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SMG1, a nonsense-mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma.
Alexander C Leeksma, Ingrid A M Derks, Brett Garrick, Aldo Jongejan, Martino Colombo, Kate Blease

Mol Oncol· February 2023

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Discovery of the c-Jun N-Terminal Kinase Inhibitor .
Mark A Nagy, Robert Hilgraf, Deborah S Mortensen, Jan Elsner, Stephen Norris, Kate Blease

J Med Chem· December 2021

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Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005.
Patrick Papa, Brandon Whitefield, Deborah S Mortensen, Dan Cashion, Dehua Huang, Kate Blease

J Med Chem· August 2021

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Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs.
Mingjun Zhang, Michael Haughey, Nai-Yu Wang, Kate Blease, Ann M Kapoun

PLoS One· July 2020

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SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate.
Mary E Matyskiela, Suzana Couto, Xinde Zheng, Gang Lu, Julia Hui, Kate Blease

Nat Chem Biol· October 2018

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Spleen Tyrosine Kinase Signaling Promotes Myeloid Cell Recruitment and Kidney Damage after Renal Ischemia/Reperfusion Injury.
Jessica Ryan, John Kanellis, Kate Blease, Frank Y Ma, David J Nikolic-Paterson

Am J Pathol· August 2016

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A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation.
Gregory D Ferguson, Mercedes Delgado, Veronique Plantevin-Krenitsky, Kristen Jensen-Pergakes, R J Bates, Kate Blease

PLoS One· July 2016

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A role for spleen tyrosine kinase in renal fibrosis in the mouse obstructed kidney.
Frank Y Ma, Kate Blease, David J Nikolic-Paterson

Life Sci· February 2016

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Spleen tyrosine kinase contributes to acute renal allograft rejection in the rat.
Sharmila Ramessur Chandran, Greg H Tesch, Yingjie Han, Naomi Woodman, William R Mulley, Kate Blease

Int J Exp Pathol· February 2015

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Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury.
Véronique Plantevin Krenitsky, Mercedes Delgado, Lisa Nadolny, Kiran Sahasrabudhe, Leticia Ayala, Kate Blease

Bioorg Med Chem Lett· February 2012

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Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor.
Véronique Plantevin Krenitsky, Lisa Nadolny, Mercedes Delgado, Leticia Ayala, Steven S Clareen, Kate Blease

Bioorg Med Chem Lett· February 2012

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Spleen tyrosine kinase promotes acute neutrophil-mediated glomerular injury via activation of JNK and p38 MAPK in rat nephrotoxic serum nephritis.
Jessica Ryan, Frank Y Ma, John Kanellis, Mercedes Delgado, Kate Blease

Lab Invest· December 2011

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Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4 and tumor necrosis factor-alpha inhibitor.
Hon-Wah Man, Peter Schafer, Lu Min Wong, Rebecca T Patterson, Laura G Corral, Kate Blease

J Med Chem· March 2009

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Therapeutics targeting IL-13 for the treatment of pulmonary inflammation and airway remodeling.
Kate Blease

Curr Opin Investig Drugs· November 2008

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Targeting kinases in asthma.
Kate Blease

Expert Opin Investig Drugs· October 2005

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Chemokines and cytokines: axis and allies in asthma and allergy.
Jane M Schuh, Kate Blease, Steven L Kunkel, Cory M Hogaboam

Cytokine Growth Factor Rev· December 2003

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Intrapulmonary targeting of RANTES/CCL5-responsive cells prevents chronic fungal asthma.
Jane M Schuh, Kate Blease, Hilke Brühl, Matthias Mack, Cory M Hogaboam

Eur J Immunol· November 2003

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Small molecule inhibitors of cell signaling: novel future therapeutics for asthma and chronic obstructive pulmonary diseases.
Kate Blease, Heather K Raymon

Curr Opin Investig Drugs· May 2003

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Emerging treatments for asthma.
Kate Blease, Alan Lewis, Heather K Raymon

Expert Opin Emerg Drugs· May 2003

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Cytokines and chemokines in allergic bronchopulmonary aspergillosis (ABPA) and experimental Aspergillus-induced allergic airway or asthmatic disease.
Cory M Hogaboam, Kate Blease, Jane M Schuh

Front Biosci· January 2003

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Eotaxin/CCL11 is involved in acute, but not chronic, allergic airway responses to Aspergillus fumigatus.
Jane M Schuh, Kate Blease, Steven L Kunkel, Cory M Hogaboam

Am J Physiol Lung Cell Mol Physiol· July 2002

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Delivery of FGF genes to wound repair cells enhances arteriogenesis and myogenesis in skeletal muscle.
John Doukas, Kate Blease, Darren Craig, Chenglie Ma, Lois A Chandler

Mol Ther· May 2002

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CXCR2 is necessary for the development and persistence of chronic fungal asthma in mice.
Jane M Schuh, Kate Blease, Cory M Hogaboam

J Immunol· February 2002

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Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma.
Kate Blease, Jane M Schuh, Claudia Jakubzick, Nicholas W Lukacs, Steven L Kunkel

Am J Pathol· February 2002

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