Publications by authors named "Brandon Whitefield"

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Discovery of Potent and Selective BCL6 Ligand-Directed Degrader (LDD), BCL6-760.
Hunter P Shunatona, Natalie Holmberg Douglas, Jayce Rhodes, William Thomas, Diogo Da Silva, Brandon Whitefield

J Med Chem· October 2025

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Correction to "Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005".
Patrick Papa, Brandon Whitefield, Deborah S Mortensen, Dan Cashion, Dehua Huang

J Med Chem· December 2024

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Correction to "Design and Synthesis of Novel Cereblon Binders for Use in Targeted Protein Degradation".
Stephen Norris, Xiaochu Ba, Jayce Rhodes, Dehua Huang, Gody Khambatta, Brandon Whitefield

J Med Chem· August 2024

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Cereblon-based Bifunctional Degrader of SOS1, BTX-6654, Targets Multiple KRAS Mutations and Inhibits Tumor Growth.
Kyle Begovich, Angela Schoolmeesters, Navin Rajapakse, Elena Martinez-Terroba, Maneesh Kumar, Brandon Whitefield

Mol Cancer Ther· April 2024

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Design and Synthesis of Novel Cereblon Binders for Use in Targeted Protein Degradation.
Stephen Norris, Xiaochu Ba, Jayce Rhodes, Dehua Huang, Gody Khambatta, Brandon Whitefield

J Med Chem· December 2023

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Identification of Small Molecule Inhibitors and Ligand Directed Degraders of Calcium/Calmodulin Dependent Protein Kinase Kinase 1 and 2 (CaMKK1/2).
Young Chen, Brandon Whitefield, Erin Nevius, Mark Hill, Joselyn DelRosario

J Med Chem· December 2023

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Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005.
Patrick Papa, Brandon Whitefield, Deborah S Mortensen, Dan Cashion, Dehua Huang

J Med Chem· August 2021

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Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma.
Joshua D Hansen, Matthew Correa, Mark A Nagy, Matt Alexander, Veronique Plantevin, Brandon Whitefield

J Med Chem· July 2020

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Discovery of mammalian target of rapamycin (mTOR) kinase inhibitor CC-223.
Deborah S Mortensen, Sophie M Perrin-Ninkovic, Graziella Shevlin, Jingjing Zhao, Garrick Packard, Brandon Whitefield

J Med Chem· July 2015

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Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115.
Deborah S Mortensen, Sophie M Perrin-Ninkovic, Graziella Shevlin, Jan Elsner, Jingjing Zhao, Brandon Whitefield

J Med Chem· July 2015

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Use of core modification in the discovery of CC214-2, an orally available, selective inhibitor of mTOR kinase.
Deborah S Mortensen, John Sapienza, Branden G S Lee, Sophie M Perrin-Ninkovic, Roy Harris, Brandon Whitefield

Bioorg Med Chem Lett· March 2013

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Enantiospecific total synthesis of the hapalindoles, fischerindoles, and welwitindolinones via a redox economic approach.
Jeremy M Richter, Yoshihiro Ishihara, Takeshi Masuda, Brandon W Whitefield, Tomás Llamas

J Am Chem Soc· December 2008

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Scope and mechanism of direct indole and pyrrole couplings adjacent to carbonyl compounds: total synthesis of acremoauxin A and oxazinin 3.
Jeremy M Richter, Brandon W Whitefield, Thomas J Maimone, David W Lin, M Pilar Castroviejo

J Am Chem Soc· October 2007

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