Publications by authors named "Roy Harris"

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Medical emergencies in hospital: The role of treatment escalation plans in out-of-hours decision-making.
Tze Yi Gan, Roy Harris, D Robin Taylor

J R Coll Physicians Edinb· December 2024

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Wound imaging software and digital platform to assist review of surgical wounds using patient smartphones: The development and evaluation of artificial intelligence (WISDOM AI study).
Melissa Rochon, Judith Tanner, James Jurkiewicz, Jacqueline Beckhelling, Akuha Aondoakaa, Roy Harris

PLoS One· December 2024

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Correction to "Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005".
Patrick Papa, Brandon Whitefield, Deborah S Mortensen, Dan Cashion, Dehua Huang, Roy Harris

J Med Chem· December 2024

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Digital wound monitoring with artificial intelligence to prioritise surgical wounds in cardiac surgery patients for priority or standard review: protocol for a randomised feasibility trial (WISDOM).
Judith Tanner, Melissa Rochon, Roy Harris, Jacqueline Beckhelling, James Jurkiewicz

BMJ Open· September 2024

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Development of Resorbable Phosphate-Based Glass Microspheres as MRI Contrast Media Agents.
Jesús Molinar-Díaz, Andi Arjuna, Nichola Abrehart, Alison McLellan, Roy Harris

Molecules· September 2024

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Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005.
Patrick Papa, Brandon Whitefield, Deborah S Mortensen, Dan Cashion, Dehua Huang, Roy Harris

J Med Chem· August 2021

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"A little (PPI) MAGIC can take you a long way" : involving children and young people in research from inception of a novel medical device to multi-centre clinical trial Roald Dahl, James and the Giant Peach (1961).
Nichola Abrehart, Kate Frost, , Roy Harris, Andrew Wragg

Res Involv Engagem· January 2021

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Feasibility Study of a New Magnetic Resonance Imaging Mini-capsule Device to Measure Whole Gut Transit Time in Paediatric Constipation.
Hayfa Sharif, Nichola Abrehart, Caroline L Hoad, Kathryn Murray, Alan C Perkins, Roy Harris

J Pediatr Gastroenterol Nutr· November 2020

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Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma.
Joshua D Hansen, Matthew Correa, Mark A Nagy, Matt Alexander, Veronique Plantevin, Roy Harris

J Med Chem· July 2020

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The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen.
Jennifer R Riggs, Mark Nagy, Jan Elsner, Paul Erdman, Dan Cashion, Roy Harris

J Med Chem· November 2017

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Discovery of mammalian target of rapamycin (mTOR) kinase inhibitor CC-223.
Deborah S Mortensen, Sophie M Perrin-Ninkovic, Graziella Shevlin, Jingjing Zhao, Garrick Packard, Roy Harris

J Med Chem· July 2015

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Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115.
Deborah S Mortensen, Sophie M Perrin-Ninkovic, Graziella Shevlin, Jan Elsner, Jingjing Zhao, Roy Harris

J Med Chem· July 2015

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Use of core modification in the discovery of CC214-2, an orally available, selective inhibitor of mTOR kinase.
Deborah S Mortensen, John Sapienza, Branden G S Lee, Sophie M Perrin-Ninkovic, Roy Harris

Bioorg Med Chem Lett· March 2013

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Discovery and optimization of thieno[2,3-d]pyrimidines as B-Raf inhibitors.
Garrick K Packard, Patrick Papa, Jennifer R Riggs, Paul Erdman, Lida Tehrani, Roy Harris

Bioorg Med Chem Lett· January 2012

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Discovery and SAR exploration of a novel series of imidazo[4,5-b]pyrazin-2-ones as potent and selective mTOR kinase inhibitors.
Deborah S Mortensen, Sophie M Perrin-Ninkovic, Roy Harris, Branden G S Lee, Graziella Shevlin

Bioorg Med Chem Lett· November 2011

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Rate limiting factors in recruitment of patients to clinical trials in cancer research: descriptive study.
Pippa Corrie, Justin Shaw, Roy Harris

BMJ· August 2003

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