Publications by authors named "Katherine Sullivan-Reed"

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ZNF251 haploinsufficiency confers PARP inhibitors resistance in BRCA1-mutated cancer cells through activation of homologous recombination.
Huan Li, Srinivas Chatla, Xiaolei Liu, Zhen Tian, Umeshkumar Vekariya, Katherine Sullivan-Reed

Cancer Lett· March 2025

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PARG is essential for Polθ-mediated DNA end-joining by removing repressive poly-ADP-ribose marks.
Umeshkumar Vekariya, Leonid Minakhin, Gurushankar Chandramouly, Mrityunjay Tyagi, Tatiana Kent, Katherine Sullivan-Reed

Nat Commun· July 2024

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Simultaneous Targeting of DNA Polymerase Theta and PARP1 or RAD52 Triggers Dual Synthetic Lethality in Homologous Recombination-Deficient Leukemia Cells.
Katherine Sullivan-Reed, Monika M Toma, Malgorzata Drzewiecka, Margaret Nieborowska-Skorska, Reza Nejati

Mol Cancer Res· October 2023

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DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Umeshkumar Vekariya, Monika Toma, Margaret Nieborowska-Skorska, Bac Viet Le, Marie-Christine Caron, Katherine Sullivan-Reed

Blood· May 2023

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and Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors.
Silvia Maifrede, Bac Viet Le, Margaret Nieborowska-Skorska, Konstantin Golovine, Katherine Sullivan-Reed

Cancer Res· October 2021

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Polθ promotes the repair of 5'-DNA-protein crosslinks by microhomology-mediated end-joining.
Gurushankar Chandramouly, Shuren Liao, Timur Rusanov, Nikita Borisonnik, Marissa L Calbert, Katherine Sullivan-Reed

Cell Rep· March 2021

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TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment.
Bac Viet Le, Paulina Podszywalow-Bartnicka, Silvia Maifrede, Katherine Sullivan-Reed, Margaret Nieborowska-Skorska

Cell Rep· October 2020

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Novel allosteric PARP1 inhibitors for the treatment of BRCA-deficient leukemia.
Elizabeth Hewlett, Monika Toma, Katherine Sullivan-Reed, John Gordo, Tomasz Sliwinski

Med Chem Res· June 2020

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Publisher Correction: Molecular basis of microhomology-mediated end-joining by purified full-length Polθ.
Samuel J Black, Ahmet Y Ozdemir, Ekaterina Kashkina, Tatiana Kent, Timur Rusanov, Katherine Sullivan-Reed

Nat Commun· April 2020

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RAD52 as a Potential Target for Synthetic Lethality-Based Anticancer Therapies.
Monika Toma, Katherine Sullivan-Reed, Tomasz Śliwiński, Tomasz Skorski

Cancers (Basel)· October 2019

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Molecular basis of microhomology-mediated end-joining by purified full-length Polθ.
Samuel J Black, Ahmet Y Ozdemir, Ekaterina Kashkina, Tatiana Kent, Timur Rusanov, Katherine Sullivan-Reed

Nat Commun· September 2019

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Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.
Silvia Maifrede, Margaret Nieborowska-Skorska, Katherine Sullivan-Reed, Yashodhara Dasgupta, Paulina Podszywalow-Bartnicka

Blood· July 2018

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Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells.
Katherine Sullivan-Reed, Elisabeth Bolton-Gillespie, Yashodhara Dasgupta, Samantha Langer, Micheal Siciliano

Cell Rep· June 2018

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IGH/MYC Translocation Associates with BRCA2 Deficiency and Synthetic Lethality to PARP1 Inhibitors.
Silvia Maifrede, Kayla Martin, Paulina Podszywalow-Bartnicka, Katherine Sullivan-Reed, Samantha K Langer

Mol Cancer Res· August 2017

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