Publications by authors named "Kay Chapman"

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A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip.
Evangelos Evangelou, Hanneke J Kerkhof, Unnur Styrkarsdottir, Evangelia E Ntzani, Steffan D Bos, Kay Chapman

Ann Rheum Dis· December 2014

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Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies.
Cristina Rodriguez-Fontenla, Manuel Calaza, Evangelos Evangelou, Ana M Valdes, Nigel Arden, Kay Chapman

Arthritis Rheumatol· April 2014

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Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data.
Katherine S Elliott, Kay Chapman, Aaron Day-Williams, Kalliope Panoutsopoulou, Lorraine Southam

Ann Rheum Dis· June 2013

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No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls.
Gavin Hudson, Kalliope Panoutsopoulou, Ian Wilson, Lorraine Southam, Nigel W Rayner, Kay Chapman

Ann Rheum Dis· January 2013

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Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

Lancet· September 2012

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Genetic factors in OA pathogenesis.
Kay Chapman, Ana M Valdes

Bone· August 2012

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Defining the power limits of genome-wide association scan meta-analyses.
Kay Chapman, Teresa Ferreira, Andrew Morris, Jennifer Asimit, Eleftheria Zeggini

Genet Epidemiol· December 2011

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A variant in MCF2L is associated with osteoarthritis.
Aaron G Day-Williams, Lorraine Southam, Kalliope Panoutsopoulou, Nigel W Rayner, Tonu Esko, Kay Chapman

Am J Hum Genet· September 2011

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The effect of genome-wide association scan quality control on imputation outcome for common variants.
Lorraine Southam, Kalliope Panoutsopoulou, N William Rayner, Kay Chapman, Caroline Durrant

Eur J Hum Genet· May 2011

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Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22.
Evangelos Evangelou, Ana M Valdes, Hanneke J M Kerkhof, Unnur Styrkarsdottir, Yanyan Zhu, Kay Chapman

Ann Rheum Dis· February 2011

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Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility.
Ingrid Meulenbelt, Steffan D Bos, Kay Chapman, Ruud van der Breggen, Jeanine J Houwing-Duistermaat

Ann Rheum Dis· January 2011

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Association of a functional microsatellite within intron 1 of the BMP5 gene with susceptibility to osteoarthritis.
James M Wilkins, Lorraine Southam, Zehra Mustafa, Kay Chapman, John Loughlin

BMC Med Genet· December 2009

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Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism.
Rainer J Egli, Lorraine Southam, James M Wilkins, Inken Lorenzen, Manuel Pombo-Suarez, Kay Chapman

Arthritis Rheum· July 2009

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Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand.
Evangelos Evangelou, Kay Chapman, Ingrid Meulenbelt, Fotini B Karassa, John Loughlin

Arthritis Rheum· June 2009

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Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations.
Ingrid Meulenbelt, Kay Chapman, Rebeca Dieguez-Gonzalez, Dongquan Shi, Aspasia Tsezou

Hum Mol Genet· April 2009

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Toll-like receptor 4 and CD14 polymorphisms in ankylosing spondylitis: evidence of a weak association in Finns.
Jennifer J Pointon, Kay Chapman, David Harvey, Anne-Marie Sims, Linda Bradbury

J Rheumatol· August 2008

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A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility.
Kay Chapman, Atsushi Takahashi, Ingrid Meulenbelt, Chris Watson, Julio Rodriguez-Lopez

Hum Mol Genet· May 2008

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An SNP in the 5'-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage.
Lorraine Southam, Julio Rodriguez-Lopez, James M Wilkins, Manuel Pombo-Suarez, Sarah Snelling, Kay Chapman

Hum Mol Genet· September 2007

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A novel LEMD3 mutation common to patients with osteopoikilosis with and without melorheostosis.
Ana R Couto, Jacome Bruges-Armas, Chris A Peach, Kay Chapman, Matthew A Brown

Calcif Tissue Int· August 2007

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Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP, and FRZB with genetic susceptibility to osteoarthritis of the knee.
Ana M Valdes, John Loughlin, Mark Van Oene, Kay Chapman, Gabriela L Surdulescu

Arthritis Rheum· January 2007

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Association of the interleukin-1 gene cluster with osteoarthritis of the hip: comment on the article by Meulenbelt et al and the letter by Smith et al.
Kay Chapman, John Loughlin

Arthritis Rheum· November 2006

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Presence of a primary hip osteoarthritis susceptibility locus on chromosome 6: comment on the article by Meenagh et al.
Kay Chapman, Andrew Carr, John Loughlin, Janet S Sinsheimer

Arthritis Rheum· March 2006

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Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population.
Zehra Mustafa, Barbara Dowling, Kay Chapman, Janet S Sinsheimer, Andrew Carr

Arthritis Rheum· November 2005

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The common HFE variants C282Y and H63D are not associated with primary OA of the hip or knee.
John Loughlin, Andrew Carr, Kay Chapman

J Rheumatol· February 2005

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Microsatellite association mapping of a primary osteoarthritis susceptibility locus on chromosome 6p12.3-q13.
Lorraine Southam, Barbara Dowling, Athena Ferreira, Lucy Marcelline, Zehra Mustafa, Kay Chapman

Arthritis Rheum· December 2004

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