Publications by authors named "Jennifer Asimit"

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Protocol for genetic discovery and fine-mapping of multivariate latent factors from high-dimensional traits.
William J Astle, Adam S Butterworth, Jennifer L Asimit

STAR Protoc· November 2025

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Combining functional annotation and multi-trait fine-mapping methods improves fine-mapping resolution at glycaemic trait loci.
Jana Soenksen, Ji Chen, Arushi Varshney, Susan Martin, Stephen C J Parker, Jennifer L Asimit

Hum Mol Genet· November 2025

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Improved genetic discovery and fine-mapping resolution through multivariate latent factor analysis of high-dimensional traits.
Feng Zhou, William J Astle, Adam S Butterworth, Jennifer L Asimit

Cell Genom· May 2025

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Accounting for heterogeneity due to environmental sources in meta-analysis of genome-wide association studies.
Siru Wang, Oyesola O Ojewunmi, Abram Kamiza, Michele Ramsay, Andrew P Morris, Jennifer L Asimit

Commun Biol· November 2024

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Leveraging information between multiple population groups and traits improves fine-mapping resolution.
Feng Zhou, Opeyemi Soremekun, Tinashe Chikowore, Segun Fatumo, Inês Barroso, Jennifer L Asimit

Nat Commun· November 2023

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Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization.
Sara M Willems, Natasha H J Ng, Juan Fernandez, Rebecca S Fine, Eleanor Wheeler, Jennifer L Asimit

Wellcome Open Res· October 2023

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Multi-trait discovery and fine-mapping of lipid loci in 125,000 individuals of African ancestry.
Abram Bunya Kamiza, Sounkou M Touré, Feng Zhou, Opeyemi Soremekun, Cheickna Cissé, Jennifer L Asimit

Nat Commun· September 2023

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Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits.
Feng Zhou, Adam S Butterworth, Jennifer L Asimit

Bioinformatics· September 2022

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50th European Mathematical Genetics Meeting (EMGM) 2022.
Jennifer Asimit

Hum Hered· April 2022

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Fine-mapping genetic associations.
Anna Hutchinson, Jennifer Asimit, Chris Wallace

Hum Mol Genet· September 2020

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Stochastic search and joint fine-mapping increases accuracy and identifies previously unreported associations in immune-mediated diseases.
Jennifer L Asimit, Daniel B Rainbow, Mary D Fortune, Nastasiya F Grinberg, Linda S Wicker

Nat Commun· July 2019

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Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations.
Yali Xue, Massimo Mezzavilla, Marc Haber, Shane McCarthy, Yuan Chen, Jennifer Asimit

Nat Commun· June 2017

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A two-stage inter-rater approach for enrichment testing of variants associated with multiple traits.
Jennifer L Asimit, Felicity Payne, Andrew P Morris, Heather J Cordell, Inês Barroso

Eur J Hum Genet· February 2017

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Trans-ethnic study design approaches for fine-mapping.
Jennifer L Asimit, Konstantinos Hatzikotoulas, Mark McCarthy, Andrew P Morris, Eleftheria Zeggini

Eur J Hum Genet· August 2016

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Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.
Momoko Horikoshi, Lorenzo Pasquali, Steven Wiltshire, Jeroen R Huyghe, Anubha Mahajan, Jennifer L Asimit

Hum Mol Genet· May 2016

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A Bayesian Approach to the Overlap Analysis of Epidemiologically Linked Traits.
Jennifer L Asimit, Kalliope Panoutsopoulou, Eleanor Wheeler, Sonja I Berndt,

Genet Epidemiol· December 2015

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The African Genome Variation Project shapes medical genetics in Africa.
Deepti Gurdasani, Tommy Carstensen, Fasil Tekola-Ayele, Luca Pagani, Ioanna Tachmazidou, Jennifer Asimit

Nature· January 2015

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Imputation of rare variants in next-generation association studies.
Jennifer L Asimit, Eleftheria Zeggini

Hum Hered· October 2013

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Genome-wide association analysis of imputed rare variants: application to seven common complex diseases.
Reedik Mägi, Jennifer L Asimit, Aaron G Day-Williams, Eleftheria Zeggini, Andrew P Morris

Genet Epidemiol· December 2012

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Testing for rare variant associations in complex diseases.
Jennifer Asimit, Eleftheria Zeggini

Genome Med· October 2012

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ARIEL and AMELIA: testing for an accumulation of rare variants using next-generation sequencing data.
Jennifer L Asimit, Aaron G Day-Williams, Andrew P Morris, Eleftheria Zeggini

Hum Hered· September 2012

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A combined functional annotation score for non-synonymous variants.
Margarida C Lopes, Chris Joyce, Graham R S Ritchie, Sally L John, Fiona Cunningham, Jennifer Asimit

Hum Hered· July 2012

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An evaluation of different meta-analysis approaches in the presence of allelic heterogeneity.
Jennifer Asimit, Aaron Day-Williams, Lina Zgaga, Igor Rudan, Vesna Boraska

Eur J Hum Genet· June 2012

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Defining the power limits of genome-wide association scan meta-analyses.
Kay Chapman, Teresa Ferreira, Andrew Morris, Jennifer Asimit, Eleftheria Zeggini

Genet Epidemiol· December 2011

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Regression models, scan statistics and reappearance probabilities to detect regions of association between gene expression and copy number.
Jennifer L Asimit, Irene L Andrulis, Shelley B Bull

Stat Med· May 2011

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