Publications by authors named "Kay Lewis"

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N
NMR Studies of Biomolecular Systems.
Lewis E Kay, Remco Sprangers

J Mol Biol· December 2025

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Using CEST NMR to Discover Previously Unobserved States on the Free Energy Surface of Proteins: Application to the L99A Cavity Mutant of T4 Lysozyme.
Ved Prakash Tiwari, Nihar Pradeep Khandave, D Flemming Hansen, Guillaume Bouvignies, Lewis E Kay

J Biol Chem· November 2025

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Atomic Resolution Interactions Regulating Partitioning of a FUS Folded RRM Domain into Model CAPRIN1 Condensates.
Rashik Ahmed, Jeffrey P Bonin, Julie D Forman-Kay, Lewis E Kay

J Am Chem Soc· September 2025

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Client-scaffold interactions suppress aggregation of a client protein in model condensates.
Rashik Ahmed, Rhea P Hudson, Julie D Forman-Kay, Lewis E Kay

Proc Natl Acad Sci U S A· August 2025

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Modulation of histone tail electrostatic potentials in nucleosome core particles by acetylation and PARylation.
Nicolas Bolik-Coulon, Philip Rößler, Michael L Nosella, Tae Hun Kim, Lewis E Kay

Proc Natl Acad Sci U S A· July 2025

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NMR-Based Measurements of Site-Specific Electrostatic Potentials of Histone Tails in Nucleosome Core Particles.
Nicolas Bolik-Coulon, Philip Rößler, Lewis E Kay

J Am Chem Soc· April 2025

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Electrostatics of salt-dependent reentrant phase behaviors highlights diverse roles of ATP in biomolecular condensates.
Yi-Hsuan Lin, Tae Hun Kim, Suman Das, Tanmoy Pal, Jonas Wessén, Lewis E Kay

Elife· March 2025

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Solution NMR goes big: Atomic resolution studies of protein components of molecular machines and phase-separated condensates.
Alexander I M Sever, Rashik Ahmed, Philip Rößler, Lewis E Kay

Curr Opin Struct Biol· February 2025

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Dynamic conformational equilibria in the active states of KRAS and NRAS.
Enrico Rennella, Chrystèle Henry, Callum J Dickson, Florian Georgescauld, Thomas E Wales, Lewis E Kay

RSC Chem Biol· January 2025

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A Tribute to a Friend, a Mentor, a Spin Master, and a Mensch - Eriks Kupce.
Lewis E Kay

J Magn Reson· December 2024

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Mapping the FF domain folding pathway via structures of transiently populated folding intermediates.
Debajyoti De, Nemika Thapliyal, Ved Prakash Tiwari, Yuki Toyama, D Flemming Hansen, Lewis E Kay

Proc Natl Acad Sci U S A· December 2024

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Structural Plasticity as a Driver of the Maturation of Pro-Interleukin-18.
Jeffrey P Bonin, James M Aramini, Lewis E Kay

J Am Chem Soc· November 2024

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Design of amyloidogenic peptide traps.
Danny D Sahtoe, Ewa A Andrzejewska, Hannah L Han, Enrico Rennella, Matthias M Schneider, Lewis E Kay

Nat Chem Biol· August 2024

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Atomic resolution map of the solvent interactions driving SOD1 unfolding in CAPRIN1 condensates.
Rashik Ahmed, Mingyang Liang, Rhea P Hudson, Atul K Rangadurai, Shuya Kate Huang, Lewis E Kay

Proc Natl Acad Sci U S A· August 2024

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Structural transitions enable interleukin-18 maturation and signaling.
Ying Dong, Jeffrey P Bonin, Pascal Devant, Zhuoyi Liang, Alexander I M Sever, Lewis E Kay

Immunity· July 2024

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AlphaFold2 as a replacement for solution NMR structure determination of small proteins: Not so fast!
Jeffrey P Bonin, James M Aramini, Ying Dong, Hao Wu, Lewis E Kay

J Magn Reson· July 2024

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Phase Separation Modulates the Thermodynamics and Kinetics of RNA Hybridization.
Atul K Rangadurai, Lisa Ruetz, Rashik Ahmed, Kristen Lo, Martin Tollinger, Lewis E Kay

J Am Chem Soc· July 2024

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Gadolinium-Based NMR Spin Relaxation Measurements of Near-Surface Electrostatic Potentials of Biomolecules.
Binhan Yu, Nicolas Bolik-Coulon, Atul K Rangadurai, Lewis E Kay, Junji Iwahara

J Am Chem Soc· July 2024

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A delayed decoupling methyl-TROSY pulse sequence for atomic resolution studies of folded proteins and RNAs in condensates.
Rashik Ahmed, Atul K Rangadurai, Lisa Ruetz, Martin Tollinger, Christoph Kreutz, Lewis E Kay

J Magn Reson· May 2024

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Cryo-EM of the Nucleosome Core Particle Bound to Ran-RCC1 Reveals a Dynamic Complex.
Shuya Kate Huang, John L Rubinstein, Lewis E Kay

Biochemistry· April 2024

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Optimization of TROSY- and anti-TROSY-based N CPMG relaxation dispersion experiments through phase cycling.
Yingxian Cui, Yangzhuoyue Jin, Yu Hou, Xiaoxu Han, Haiyan Cao, Lewis E Kay

J Magn Reson· April 2024

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Beyond slow two-state protein conformational exchange using CEST: applications to three-state protein interconversion on the millisecond timescale.
Ved Prakash Tiwari, Debajyoti De, Nemika Thapliyal, Lewis E Kay, Pramodh Vallurupalli

J Biomol NMR· March 2024

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Exploring Host-Guest Interactions within a 600 kDa DegP Protease Cage Complex Using Hydrodynamics Measurements and Methyl-TROSY NMR.
Robert W Harkness, Huaying Zhao, Yuki Toyama, Peter Schuck, Lewis E Kay

J Am Chem Soc· March 2024

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Poly(ADP-ribosyl)ation enhances nucleosome dynamics and organizes DNA damage repair components within biomolecular condensates.
Michael L Nosella, Tae Hun Kim, Shuya Kate Huang, Robert W Harkness, Monica Goncalves, Lewis E Kay

Mol Cell· February 2024

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Activation of caspase-9 on the apoptosome as studied by methyl-TROSY NMR.
Alexander I M Sever, T Reid Alderson, Enrico Rennella, James M Aramini, Zi Hao Liu, Lewis E Kay

Proc Natl Acad Sci U S A· December 2023

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