Publications by authors named "Kay Xiang"

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The Discovery of SWI/SNF Chromatin Remodeling Activity as a Novel and Targetable Dependency in Uveal Melanoma.
Florencia Rago, GiNell Elliott, Ailing Li, Kathleen Sprouffske, Grainne Kerr, Kay X Xiang

Mol Cancer Ther· October 2020

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Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers.
Julien P N Papillon, Katsumasa Nakajima, Christopher D Adair, Jonathan Hempel, Andriana O Jouk, Kay Xiang

J Med Chem· November 2018

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Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers.
Gregory R Hoffman, Rami Rahal, Frank Buxton, Kay Xiang, Gregory McAllister

Proc Natl Acad Sci U S A· February 2014

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PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers.
Susan Wee, Zainab Jagani, Kay Xiaoqin Xiang, Alice Loo, Marion Dorsch

Cancer Res· May 2009

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