Publications by authors named "Susan Wee"

Claim this Profile
D
Design, Synthesis, and T Cell Checkpoint Combination Potential Of First-In-Class DGKα/ζ Inhibitor BMS-986408.
Denise C Grünenfelder, Upender Velaparthi, Jayakumar S Warrier, Louis Chupak, Chetan Padmakar Darne, Susan Wee

J Med Chem· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2.
Joshua R Hummel, Kai-Jiong Xiao, Jeffrey C Yang, Leslie B Epling, Ken Mukai, Susan Wee

J Med Chem· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity.
Michael Wichroski, Joseph Benci, Si-Qi Liu, Louis Chupak, Jie Fang, Susan Wee

Sci Transl Med· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of Potent, Dual-Inhibitors of Diacylglycerol Kinases Alpha and Zeta Guided by Phenotypic Optimization.
Louis Chupak, Michael Wichroski, Xiaofan Zheng, Min Ding, Scott Martin, Susan Wee

ACS Med Chem Lett· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DGKζ exerts greater control than DGKα over CD8 T cell activity and tumor inhibition.
Junchen Gu, Cindy Wang, Carolyn Cao, Jinwen Huang, Sandra Holzhauer, Susan Wee

Oncoimmunology· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design.
Ashvinikumar V Gavai, Derek Norris, George Delucca, David Tortolani, John S Tokarski, Susan Wee

J Med Chem· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of Pyridazinone and Pyrazolo[1,5-]pyridine Inhibitors of C-Terminal Src Kinase.
Daniel P O'Malley, Vijay Ahuja, Brian Fink, Carolyn Cao, Cindy Wang, Susan Wee

ACS Med Chem Lett· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of Casein Kinase 2 Disrupts Differentiation of Myeloid Cells in Cancer and Enhances the Efficacy of Immunotherapy in Mice.
Ayumi Hashimoto, Chan Gao, Jerome Mastio, Andrew Kossenkov, Scott I Abrams, Susan Wee

Cancer Res· October 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Systemic Loss of C-terminal Src Kinase Expression Elicits Spontaneous Suppurative Inflammation in Conditional Knockout Mice.
Lisa D Berman-Booty, Rukiye Eraslan, Umesh Hanumegowda, Glenn H Cantor, Denise I Bounous, Susan Wee

Vet Pathol· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression.
Ryan Lenhart, Stefan Kirov, Heshani Desilva, Jian Cao, Ming Lei, Susan Wee

Mol Cancer Ther· October 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting epigenetic regulators for cancer therapy.
Susan Wee, Dash Dhanak, Haitao Li, Scott A Armstrong, Robert A Copeland

Ann N Y Acad Sci· February 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells.
Saskia M Brachmann, Irmgard Hofmann, Christian Schnell, Christine Fritsch, Susan Wee

Proc Natl Acad Sci U S A· December 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
F-box-directed CRL complex assembly and regulation by the CSN and CAND1.
Michael W Schmidt, Philip R McQuary, Susan Wee, Kay Hofmann, Dieter A Wolf

Mol Cell· September 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers.
Susan Wee, Zainab Jagani, Kay Xiaoqin Xiang, Alice Loo, Marion Dorsch

Cancer Res· May 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Single-vector inducible lentiviral RNAi system for oncology target validation.
Dmitri Wiederschain, Susan Wee, Lin Chen, Alice Loo, Guizhi Yang

Cell Cycle· February 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PTEN-deficient cancers depend on PIK3CB.
Susan Wee, Dmitri Wiederschain, Sauveur-Michel Maira, Alice Loo, Christine Miller

Proc Natl Acad Sci U S A· September 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Class IA phosphoinositide 3-kinase isoforms and human tumorigenesis: implications for cancer drug discovery and development.
Susan Wee, Christoph Lengauer, Dmitri Wiederschain

Curr Opin Oncol· January 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
W
Why is cancer drug discovery so difficult?
Alexander Kamb, Susan Wee, Christoph Lengauer

Nat Rev Drug Discov· February 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes.
Chunshui Zhou, Fatih Arslan, Susan Wee, Srinivasan Krishnan, Alexander R Ivanov

BMC Biol· May 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability.
Susan Wee, Rory K Geyer, Takashi Toda, Dieter A Wolf

Nat Cell Biol· April 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases?
Dieter A Wolf, Chunshui Zhou, Susan Wee

Nat Cell Biol· December 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases.
Rory Geyer, Susan Wee, Scott Anderson, John Yates, Dieter A Wolf

Mol Cell· September 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p.
Chunshui Zhou, Susan Wee, Edward Rhee, Michael Naumann, Wolfgang Dubiel

Mol Cell· April 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Conservation of the COP9/signalosome in budding yeast.
Susan Wee, Bettina Hetfeld, Wolfgang Dubiel, Dieter A Wolf

BMC Genet· August 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis