Publications by authors named "Kazuko Inoue"

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Structure and properties of an oxidative metabolite of 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide generated by aldehyde oxidase.
Kazuko Inoue, Motoharu Kakiki, Takafumi Komori

Drug Metab Dispos· October 2025

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Versatile intact LC-MS method for evaluating the drug-antibody ratio and drug load distribution of antibody-drug conjugates in human plasma.
Noritaka Hashii, Yusuke Haruyama, Ryu Hirayama, Ryo Kajita, Yuki Kishino, Kazuko Inoue

J Chromatogr B Analyt Technol Biomed Life Sci· May 2025

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In Vitro Metabolism of 2-Methoxy-N-[3-[4-[3-methyl-4-[(6-methyl- 3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide (CP-724,714) by Aldehyde Oxidase and Predicting Its Percent Contribution Relative to CYP-Mediated Metabolism.
Kazuko Inoue, Kiyomi Kikuchi, Kazumi Takahashi, Seiji Hitaoka, Kazutomi Kusano

Drug Metab Dispos· August 2023

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Determination of drug-to-antibody ratio of antibody-drug conjugate in biological samples using microflow-liquid chromatography/high-resolution mass spectrometry.
Kazuko Inoue, Toshiki Mochizuki, Nana Kasamori, Takafumi Komori

Bioanalysis· December 2022

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Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
Anfeng Mu, Asuka Hira, Akira Niwa, Mitsujiro Osawa, Kenichi Yoshida, Kazuko Inoue

Blood· April 2021

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Bioactivation of diclofenac in human hepatocytes and the proposed human hepatic proteins modified by reactive metabolites.
Kazuko Inoue, Hitoshi Mizuo, Tomomi Ishida, Takafumi Komori, Kazutomi Kusano

Xenobiotica· August 2020

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Crizotinib, a MET inhibitor, prevents peritoneal dissemination in pancreatic cancer.
Soichi Takiguchi, Kazuko Inoue, Kimihiko Matsusue, Masayuki Furukawa, Norihiro Teramoto

Int J Oncol· July 2017

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Comparison of the Reactivity of Trapping Reagents toward Electrophiles: Cysteine Derivatives Can Be Bifunctional Trapping Reagents.
Kazuko Inoue, Katsuyuki Fukuda, Tsutomu Yoshimura, Kazutomi Kusano

Chem Res Toxicol· August 2015

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Oxidative metabolic pathway of lenvatinib mediated by aldehyde oxidase.
Kazuko Inoue, Hitoshi Mizuo, Shinki Kawaguchi, Katsuyuki Fukuda, Kazutomi Kusano

Drug Metab Dispos· August 2014

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Involvement of CXCL14 in osteolytic bone metastasis from lung cancer.
Soichi Takiguchi, Natsuki Korenaga, Kazuko Inoue, Erika Sugi, Yasufumi Kataoka

Int J Oncol· April 2014

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The bisphosphonate incadronate inhibits intraperitoneal dissemination in an in vivo pancreatic cancer model.
Soichi Takiguchi, Yukiko Nishino, Kazuko Inoue, Miyako Ikeda, Yasufumi Kataoka

Oncol Rep· July 2012

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Unique metabolic pathway of [(14)C]lenvatinib after oral administration to male cynomolgus monkey.
Kazuko Inoue, Naoki Asai, Hitoshi Mizuo, Katsuyuki Fukuda, Kazutomi Kusano

Drug Metab Dispos· April 2012

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Risk factors for term small for gestational age infants in women with low prepregnancy body mass index.
Hiroko Watanabe, Kazuko Inoue, Masako Doi, Momoyo Matsumoto, Kayoko Ogasawara

J Obstet Gynaecol Res· June 2010

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A trapping method for semi-quantitative assessment of reactive metabolite formation using [35S]cysteine and [14C]cyanide.
Kazuko Inoue, Yoshihiro Shibata, Hiroyuki Takahashi, Tomoyuki Ohe, Masato Chiba

Drug Metab Pharmacokinet· October 2009

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Aromatic substitution reaction of 2-chloropyridines catalyzed by microsomal glutathione S-transferase 1.
Kazuko Inoue, Tomoyuki Ohe, Kenichi Mori, Takeshi Sagara, Yasuyuki Ishii

Drug Metab Dispos· September 2009

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[Regulatory factors for images of the elderly among elementary school students assessed through secular trend analyses by frequency of inter-exchange with "REPRINTS" senior volunteers].
Yoshinori Fujiwara, Naoki Watanabe, Mariko Nishi, Sangyoon Lee, Hiromi Ohba, Kazuko Inoue

Nihon Koshu Eisei Zasshi· September 2007

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Restricting weight gain during pregnancy in Japan: a controversial factor in reducing perinatal complications.
Hiroko Tsukamoto, Hideoki Fukuoka, Kazuko Inoue, Mieko Koyasu, Yasushi Nagai

Eur J Obstet Gynecol Reprod Biol· July 2007

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[An intergenerational health promotion program involving older adults in urban areas. "Research of Productivity by Intergenerational Sympathy (REPRINTS)": first-year experience and short-term effects].
Yoshinori Fujiwara, Mariko Nishi, Naoki Watanabe, Sangyoon Lee, Kazuko Inoue

Nihon Koshu Eisei Zasshi· September 2006

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Effect of ATP on preadipocyte migration and adipocyte differentiation by activating P2Y receptors in 3T3-L1 cells.
Mariko Omatsu-Kanbe, Kazuko Inoue, Yusuke Fujii, Takefumi Yamamoto, Takahiro Isono

Biochem J· January 2006

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Identification of endogenous surrogate ligands for human P2Y receptors through an in silico search.
Takeshi Hiramoto, Yosuke Nonaka, Kazuko Inoue, Takefumi Yamamoto, Mariko Omatsu-Kanbe

J Pharmacol Sci· May 2004

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Association of pharmacokinetic (CYP2C9) and pharmacodynamic (factors II, VII, IX, and X; proteins S and C; and gamma-glutamyl carboxylase) gene variants with warfarin sensitivity.
Eriko Shikata, Ichiro Ieiri, Shingo Ishiguro, Hironao Aono, Kazuko Inoue

Blood· April 2004

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Beta-glycosylamidine as a ligand for affinity chromatography tailored to the glycon substrate specificity of beta-glycosidases.
Kazuko Inoue, Jun Hiratake, Masaharu Mizutani, Masayasu Takada, Mikio Yamamoto

Carbohydr Res· July 2003

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[Evaluation of community-oriented education in the public health course for medical students].
Hiroko Fujita, Kumiko Herai, Kazuko Inoue, Gyokushu Kyo, Shinko Ninotani

Nihon Koshu Eisei Zasshi· June 2002

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