Publications by authors named "Kehan Ren"

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Mutant p53 promotes clonal hematopoiesis through generating a chronic inflammatory microenvironment.
Sisi Chen, Sergio Barajas, Sasidhar Vemula, Yuxia Yang, Ed Simpson, Kehan Ren

J Clin Invest· December 2025

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Overall cancer risk in people with deleterious germline variants.
Sophia C Korotev, Jason X Cheng, Yogameenakshi Haribabu, Joshua Strauss, Salina Dominguez, Kehan Ren

Haematologica· September 2025

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DDX41 resolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death.
Honghao Bi, Kehan Ren, Pan Wang, Ermin Li, Xu Han, Renee Ma

Nat Commun· August 2025

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3D map-guided modeling of functional endometrial tissue using multi-compartment assembloids.
Kehan A Ren, Victoria Duarte-Alvarado, Xin Di Zhou, Bryan Ho, André Forjaz

bioRxiv· August 2025

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PPIL2 is a target of the JAK2/STAT5 pathway and promotes myeloproliferation via degradation of p53.
Pan Wang, Xu Han, Kehan Ren, Ermin Li, Honghao Bi

J Clin Invest· July 2025

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Development of iPSC-derived human bone marrow organoid for autonomous hematopoiesis and patient-derived HSPC engraftment.
Kehan Ren, Ermin Li, Inci Aydemir, Yijie Liu, Xu Han

Blood Adv· January 2025

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Pleckstrin-2 Mediates the Activation of AKT in Prostate Cancer and Is Repressed by Androgen Receptor.
Xu Han, Ali Zhang, Pan Wang, Honghao Bi, Kehan Ren

Am J Pathol· October 2024

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DDX41 dissolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death.
Honghao Bi, Kehan Ren, Pan Wang, Ermin Li, Xu Han

bioRxiv· October 2024

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Combined assembloid modeling and 3D whole-organ mapping captures the microanatomy and function of the human fallopian tube.
Ashleigh J Crawford, André Forjaz, Joanna Bons, Isha Bhorkar, Triya Roy, Kehan Ren

Sci Adv· September 2024

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A 3D in vitro assay to study combined immune cell infiltration and cytotoxicity.
Ashleigh J Crawford, Adrian Johnston, Wenxuan Du, Eban A Hanna, David Schell, Kehan Ren

bioRxiv· March 2024

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mDia formins form hetero-oligomers and cooperatively maintain murine hematopoiesis.
Zhaofeng Li, Meng Su, Xinshu Xie, Pan Wang, Honghao Bi, Kehan Ren

PLoS Genet· December 2023

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Precision-engineered biomimetics: the human fallopian tube.
Ashleigh J Crawford, André Forjaz, Isha Bhorkar, Triya Roy, David Schell, Kehan Ren

bioRxiv· June 2023

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Clonal hematopoiesis and bone marrow inflammation.
Xinshu Xie, Meng Su, Kehan Ren, Xuezhen Ma, Zhiyi Lv

Transl Res· May 2023

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Metformin induces mitochondrial fission and reduces energy metabolism by targeting respiratory chain complex I in hepatic stellate cells to reverse liver fibrosis.
Ying Su, Chenjian Hou, Meili Wang, Kehan Ren, Danmei Zhou

Int J Biochem Cell Biol· April 2023

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Targeted lipidomics analysis of lysine 179 acetylation of ACSF2 in rat hepatic stellate cells.
Meili Wang, Ying Su, Chenjian Hou, Kehan Ren, Xiaoli Liu

Prostaglandins Other Lipid Mediat· December 2022

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Chromatin reconstruction during mouse terminal erythropoiesis.
Honghao Bi, Ye Hou, Juan Wang, Zongjun Xia, Dongmei Wang, Kehan Ren

iScience· December 2022

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Bone marrow-confined IL-6 signaling mediates the progression of myelodysplastic syndromes to acute myeloid leukemia.
Yang Mei, Kehan Ren, Yijie Liu, Annabel Ma, Zongjun Xia

J Clin Invest· September 2022

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Mitigation of liver fibrosis via hepatic stellate cells mitochondrial apoptosis induced by metformin.
Ying Su, Shan Lu, Chenjian Hou, Kehan Ren, Meili Wang

Int Immunopharmacol· July 2022

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Proteome remodeling and organelle clearance in mammalian terminal erythropoiesis.
Kehan Ren, Ermin Li, Peng Ji

Curr Opin Hematol· May 2022

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RACGAP1 modulates ECT2-Dependent mitochondrial quality control to drive breast cancer metastasis.
Kehan Ren, Danmei Zhou, Meili Wang, Ermin Li, Chenjian Hou

Exp Cell Res· March 2021

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Long non-coding RNA RACGAP1P promotes breast cancer invasion and metastasis via miR-345-5p/RACGAP1-mediated mitochondrial fission.
Danmei Zhou, Kehan Ren, Meili Wang, Jigang Wang, Ermin Li

Mol Oncol· February 2021

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BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy.
Ermin Li, Xiuya Li, Jie Huang, Chen Xu, Qianqian Liang, Kehan Ren

Protein Cell· September 2020

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SETDB1 induces epithelial‑mesenchymal transition in breast carcinoma by directly binding with Snail promoter.
Wenlin Yang, Ying Su, Chenjian Hou, Linlin Chen, Danmei Zhou, Kehan Ren, Renya Zhang

Oncol Rep· February 2019

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Erythropoietin-producing hepatocellular A6 overexpression is a novel biomarker of poor prognosis in patients with breast cancer.
Danmei Zhou, Kehan Ren, Jigang Wang, Hong Ren, Wenlin Yang

Oncol Lett· April 2018

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HCRP1 inhibits TGF-β induced epithelial-mesenchymal transition in hepatocellular carcinoma.
Wenlin Yang, Ji-Gang Wang, Jiawen Xu, Danmei Zhou, Kehan Ren

Int J Oncol· April 2017

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