Publications by authors named "Keitaro Hashimoto"

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Emerging antiarrhythmic agents: a personal view from the Far East.
Keitaro Hashimoto

Expert Opin Emerg Drugs· March 2011

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Torsades de pointes liability inter-model comparisons: the experience of the QT PRODACT initiative.
Keitaro Hashimoto

Pharmacol Ther· August 2008

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Cardiovascular profile of the canine torsades de pointes arrhythmia model assessed by echocardiographic and haemodynamic methods.
Akira Takahara, Atsushi Sugiyama, Yoshioki Satoh, Hiroshi Iwasaki, Yuji Nakamura, Keitaro Hashimoto

Basic Clin Pharmacol Toxicol· July 2007

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Arrhythmia models for drug research: classification of antiarrhythmic drugs.
Keitaro Hashimoto

J Pharmacol Sci· April 2007

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Analysis of proarrhythmic potential of antipsychotics risperidone and olanzapine in anesthetized dogs.
Kentaro Ando, Atsushi Sugiyama, Akira Takahara, Yoshioki Satoh, Tomomichi Ishizaka, Keitaro Hashimoto

Eur J Pharmacol· March 2007

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Pravastatin inhibits arrhythmias induced by coronary artery ischemia in anesthetized rats.
Jianguang Chen, Hua Shen, Yoshinobu Nagasawa, Kazuhiro Mitsui, Kunio Tsurugi, Keitaro Hashimoto

J Pharmacol Sci· March 2007

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Analysis of arrhythmogenic profile in a canine model of chronic atrioventricular block by comparing in vitro effects of the class III antiarrhythmic drug nifekalant on the ventricular action potential indices between normal heart and atrioventricular block heart.
Akira Takahara, Hideki Nakamura, Hideaki Nouchi, Takeshi Tamura, Toshikazu Tanaka, Keitaro Hashimoto

J Pharmacol Sci· February 2007

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Comparison of four rate-correction algorithms for the ventricular repolarization period in assessing net effects of IKr blockers in dogs.
Akira Takahara, Atsushi Sugiyama, Yoshioki Satoh, Keitaro Hashimoto

J Pharmacol Sci· December 2006

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Topics on the Na+/Ca2+ exchanger: involvement of Na+/Ca2+ exchange system in cardiac triggered activity.
Nobuo Homma, Md Shah Amran, Yoshinobu Nagasawa, Keitaro Hashimoto

J Pharmacol Sci· September 2006

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Characterization of the halothane-anesthetized guinea-pig heart as a model to detect the K+ channel blocker-induced QT-interval prolongation.
Akira Takahara, Atsushi Sugiyama, Keitaro Hashimoto

Biol Pharm Bull· April 2006

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Long-term bradycardia caused by atrioventricular block can remodel the canine heart to detect the histamine H1 blocker terfenadine-induced torsades de pointes arrhythmias.
Akira Takahara, Atsushi Sugiyama, Yuko Ishida, Yoshioki Satoh, Kai Wang, Keitaro Hashimoto

Br J Pharmacol· March 2006

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Acute hypokalemia may not be an effective way to sensitize the in situ canine heart for sparfloxacin-induced long QT syndrome.
Katsuyoshi Chiba, Atsushi Sugiyama, Kazuo Watanabe, Kiyoshi Takasuna, Keitaro Hashimoto

J Pharmacol Sci· January 2006

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Reduction of repolarization reserve by halothane anaesthesia sensitizes the guinea-pig heart for drug-induced QT interval prolongation.
Akira Takahara, Atsushi Sugiyama, Keitaro Hashimoto

Br J Pharmacol· October 2005

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Halothane sensitizes the guinea-pig heart to pharmacological IKr blockade: comparison with urethane anesthesia.
Yasue Sakaguchi, Atsushi Sugiyama, Shuji Takao, Yasuki Akie, Akira Takahara, Keitaro Hashimoto

J Pharmacol Sci· October 2005

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Effectiveness of oral magnesium in a patient with ventricular tachycardia due to hypomagnesemia.
Atsutoshi Tsuji, Kiyoshi Araki, Katsuhiro Maeyama, Keitaro Hashimoto

J Cardiovasc Pharmacol Ther· September 2005

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Effects of KB-R9032, a new Na+/H+ exchange inhibitor, on canine coronary occlusion/reperfusion-induced ventricular arrhythmias.
Chikaomi Yamada, YiXue Xue, Daisuke Chino, Keitaro Hashimoto

J Pharmacol Sci· August 2005

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Practical application of guinea pig telemetry system for QT evaluation.
Motohiro Shiotani, Takuma Harada, Junko Abe, Yasufusa Sawada, Keitaro Hashimoto

J Toxicol Sci· August 2005

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A simple in vivo atrial fibrillation model of rat induced by transesophageal atrial burst pacing.
Atsushi Sugiyama, Akira Takahara, Sachiko Honsho, Yuji Nakamura, Keitaro Hashimoto

J Pharmacol Sci· July 2005

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A red wine vinegar beverage can inhibit the renin-angiotensin system: experimental evidence in vivo.
Sachiko Honsho, Atsushi Sugiyama, Akira Takahara, Yoshioki Satoh, Yuji Nakamura, Keitaro Hashimoto

Biol Pharm Bull· July 2005

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Comparison of the direct negative dromotropic effect of a new calcium channel blocker, cilnidipine, with that of nicardipine.
Atsushi Sugiyama, Yoshioki Satoh, Akira Takahara, Kentaro Ando, Yuji Nakamura, Keitaro Hashimoto

Heart Vessels· May 2005

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The endothelium-dependent vasodilator action of a new beverage made of red wine vinegar and grape juice.
Akira Takahara, Atsushi Sugiyama, Sachiko Honsho, Yasue Sakaguchi, Yasuki Akie, Keitaro Hashimoto

Biol Pharm Bull· April 2005

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Antiarrhythmic properties of a prior oral loading of amiodarone in in vivo canine coronary ligation/reperfusion-induced arrhythmia model: comparison with other class III antiarrhythmic drugs.
Yoshinobu Nagasawa, Jianguang Chen, Keitaro Hashimoto

J Pharmacol Sci· March 2005

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Effects of SEA0400, a Na+/Ca2+ exchange inhibitor, on ventricular arrhythmias in the in vivo dogs.
Yoshinobu Nagasawa, Bing-Mei Zhu, Jianguang Chen, Kazunori Kamiya, Shigeki Miyamoto, Keitaro Hashimoto

Eur J Pharmacol· January 2005

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The antipsychotic and antiemetic drug prochlorperazine delays the ventricular repolarization of the in situ canine heart.
Yoshioki Satoh, Atsushi Sugiyama, Akira Takahara, Kentaro Ando, Kai Wang, Keitaro Hashimoto

J Pharmacol Sci· January 2005

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Halothane sensitizes the canine heart to pharmacological IKr blockade.
Akira Takahara, Atsushi Sugiyama, Yoshioki Satoh, Kai Wang, Sachiko Honsho, Keitaro Hashimoto

Eur J Pharmacol· January 2005

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