Publications by authors named "Kentaro Ando"

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Dasatinib can Impair Left Ventricular Mechanical Function But May Lack Proarrhythmic Effect: A Proposal of Non-clinical Guidance for Predicting Clinical Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors.
Hiroko Izumi-Nakaseko, Masachika Fujiyoshi, Mihoko Hagiwara-Nagasawa, Ai Goto, Koki Chiba, Kentaro Ando

Cardiovasc Toxicol· February 2020

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Precise safety pharmacology studies of lapatinib for onco-cardiology assessed using in vivo canine models.
Kentaro Ando, Takeshi Wada, Xin Cao

Sci Rep· January 2020

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Electropharmacological effects of intracellular Ca handling modulator caldaret on the heart assessed in the halothane-anesthetized dogs.
Atsushi Sugiyama, Mihoko Hagiwara-Nagasawa, Ryuichi Kambayashi, Ai Goto, Koki Chiba, Kentaro Ando

J Pharmacol Sci· March 2019

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Analysis of Safety Margin of Lithium Carbonate Against Cardiovascular Adverse Events Assessed in the Halothane-Anesthetized Dogs.
Ai Goto, Yuji Nakamura, Nur Jaharat Lubna, Koki Chiba, Mihoko Hagiwara-Nagasawa, Kentaro Ando

Cardiovasc Toxicol· December 2018

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Use of microminipigs for unveiling unknown mechanisms of azithromycin-induced cardiovascular death.
Ai Goto, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Kumiko Kitta, Kiyotaka Hoshiai, Kentaro Ando

J Pharmacol Sci· November 2018

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Effects of Red Wine Vinegar Beverage on the Colonic Tissue of Rodents: Biochemical, Functional and Pharmacological Analyses.
Azjargal Enkhsaikhan, Akira Takahara, Yuji Nakamura, Ai Goto, Koki Chiba, Kentaro Ando

Biol Pharm Bull· August 2018

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Comparison of electropharmacological effects between terfenadine and its active derivative fexofenadine using a cross-over study in halothane-anesthetized dogs to analyze variability of pharmacodynamic and pharmacokinetic profiles of terfenadine and torsadogenic risk of fexofenadine.
Kentaro Ando, Yuji Nakamura, Mihoko Hagiwara-Nagasawa, Hiroyuki Harada, Hiroyoshi Miyamoto

J Toxicol Sci· August 2018

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Electropharmacological characterization of microminipigs as a laboratory animal using anti-influenza virus drug oseltamivir.
Nur Jaharat Lubna, Yuji Nakamura, Mihoko Hagiwara-Nagasawa, Ai Goto, Koki Chiba, Kentaro Ando

J Toxicol Sci· August 2018

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Sunitinib does not acutely alter left ventricular systolic function, but induces diastolic dysfunction.
Takeshi Wada, Kentaro Ando, Atsuhiko T Naito, Yuji Nakamura, Ai Goto

Cancer Chemother Pharmacol· July 2018

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In vivo Analysis of the Anti-atrial Fibrillatory, Proarrhythmic and Cardiodepressive Profiles of Dronedarone as a Guide for Safety Pharmacological Evaluation of Antiarrhythmic Drugs.
Yoshiyuki Motokawa, Yuji Nakamura, Mihoko Hagiwara-Nagasawa, Ai Goto, Koki Chiba, Kentaro Ando

Cardiovasc Toxicol· June 2018

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Analysis of torsadogenic and pharmacokinetic profile of E-4031 in dogs bridging the gap of information between in vitro proarrhythmia assay and clinical observation in human subjects.
Ai Goto, Hiroko Izumi-Nakaseko, Mihoko Hagiwara-Nagasawa, Koki Chiba, Kentaro Ando

J Pharmacol Sci· June 2018

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Effects of moxifloxacin on the proarrhythmic surrogate markers in healthy Filipino subjects: Exposure-response modeling using ECG data of thorough QT/QTc study.
Suchitra Matsukura, Yuji Nakamura, Kiyotaka Hoshiai, Takashi Hayashi, Tadashi Koga, Kentaro Ando

J Pharmacol Sci· April 2018

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Amitriptyline May Have Possibility to Induce Brugada Syndrome Rather than Long QT Syndrome.
Nur Jaharat Lubna, Takeshi Wada, Yuji Nakamura, Koki Chiba, Xin Cao, Kentaro Ando

Cardiovasc Toxicol· February 2018

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Changes of electrocardiogram and hemodynamics in response to dipyridamole: In vivo comparative analyses using anesthetized beagle dogs and microminipigs.
Kentaro Ando, Akira Takahara, Yuji Nakamura, Takeshi Wada, Koki Chiba

J Pharmacol Sci· February 2018

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Sensitivity and Reliability of Halothane-anaesthetized Microminipigs to Assess Risk of Drug-induced Long QT Syndrome.
Xin Cao, Takeshi Wada, Yuji Nakamura, Suchitra Matsukura, Hiroko Izumi-Nakaseko, Kentaro Ando

Basic Clin Pharmacol Toxicol· December 2017

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Development of correction formula for field potential duration of human induced pluripotent stem cell-derived cardiomyocytes sheets.
Hiroko Izumi-Nakaseko, Yasunari Kanda, Yuji Nakamura, Mihoko Hagiwara-Nagasawa, Takeshi Wada, Kentaro Ando

J Pharmacol Sci· September 2017

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Characterization of human iPS cell-derived cardiomyocyte sheets as a model to detect drug-induced conduction disturbance.
Hiroko Izumi-Nakaseko, Yuji Nakamura, Takeshi Wada, Kentaro Ando, Yasunari Kanda

J Toxicol Sci· August 2017

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Analysis of proarrhythmic potential of an atypical antipsychotic drug paliperidone in the halothane-anesthetized dogs.
Koki Chiba, Takeshi Wada, Yuji Nakamura, Xin Cao, Mihoko Hagiwara-Nagasawa, Kentaro Ando

J Pharmacol Sci· August 2017

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Assessment of Safety Margin of an Antipsychotic Drug Haloperidol for Torsade de Pointes Using the Chronic Atrioventricular Block Dogs.
Hiroko Izumi-Nakaseko, Yuji Nakamura, Xin Cao, Takeshi Wada, Kentaro Ando

Cardiovasc Toxicol· July 2017

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Efficacy of Precordial Percussion Pacing Assessed in a Cardiac Standstill Microminipig Model.
Takeshi Wada, Hiroshi Ohara, Yuji Nakamura, Xin Cao, Hiroko Izumi-Nakaseko, Kentaro Ando

Circ J· July 2017

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Pharmacological characterization of microminipig as a model to assess the drug-induced cardiovascular responses for non-clinical toxicity and/or safety pharmacology studies.
Hirofumi Yokoyama, Yuji Nakamura, Hiroyuki Saito, Yukitoshi Nagayama, Kiyotaka Hoshiai, Kentaro Ando

J Toxicol Sci· May 2017

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Cardiac safety profile of sildenafil: chronotropic, inotropic and coronary vasodilator effects in the canine isolated, blood-perfused heart preparations.
Nur Jaharat Lubna, Yuji Nakamura, Xin Cao, Takeshi Wada, Hiroko Izumi-Nakaseko, Kentaro Ando

J Toxicol Sci· April 2017

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Characterization of microminipigs as an in vivo experimental model for cardiac safety pharmacology.
Suchitra Matsukura, Yuji Nakamura, Xin Cao, Takeshi Wada, Hiroko Izumi-Nakaseko, Kentaro Ando

J Pharmacol Sci· February 2017

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L/N-type Ca channels blocker cilnidipine ameliorated the repolarization abnormality in a chronic hemodialysis patient.
Xin Cao, Yuji Nakamura, Takeshi Wada, Hiroko Izumi-Nakaseko, Kentaro Ando

Heart Vessels· January 2017

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Assessment of the Anti-anginal Effect of Tetramethylpyrazine Using Vasopressin-Induced Angina Model Rats.
Xin Cao, Yuji Nakamura, Takeshi Wada, Takuya Kishie, Azjargal Enkhsaikhan, Kentaro Ando

Biol Pharm Bull· January 2017

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