Publications by authors named "Keith Bowman"

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Preclinical evaluation of stereopure antisense oligonucleotides for allele-selective lowering of mutant .
Naoki Iwamoto, Yuanjing Liu, Maria Frank-Kamenetsky, Abbie Maguire, Wei Chou Tseng, Keith Bowman

Mol Ther Nucleic Acids· September 2024

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Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS.
Pachamuthu Kandasamy, Yuanjing Liu, Vincent Aduda, Sandheep Akare, Rowshon Alam, Keith Bowman

Nucleic Acids Res· June 2022

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Stereochemistry Enhances Potency, Efficacy, and Durability of Antisense Oligonucleotides In Vitro and In Vivo in Multiple Species.
Michael Byrne, Vinod Vathipadiekal, Luciano Apponi, Naoki Iwamoto, Pachamuthu Kandasamy, Keith Bowman

Transl Vis Sci Technol· January 2021

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Effect of Porosity on Strength Distribution of Microcrystalline Cellulose.
Özgür Keleṣ, Nicholas P Barcenas, Daniel H Sprys, Keith J Bowman

AAPS PharmSciTech· December 2015

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Real time measurement of PEG shedding from lipid nanoparticles in serum via NMR spectroscopy.
Stephen C Wilson, Jeremy L Baryza, Aimee J Reynolds, Keith Bowman, Mark E Keegan

Mol Pharm· February 2015

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Biodistribution and metabolism studies of lipid nanoparticle-formulated internally [3H]-labeled siRNA in mice.
Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Keith Bowman

Drug Metab Dispos· March 2014

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Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes.
Maziyar Saberi, David Bjelica, Simon Schenk, Takeshi Imamura, Gautam Bandyopadhyay, Keith Bowman

Am J Physiol Endocrinol Metab· November 2009

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The Nevada Vital Aging Initiative: a private-public partnership to study early predictors of dementia.
Leon Thal, Lewis Kuller, Keith Bowman, John Breitner, Denis Evans

Alzheimers Dement· January 2007

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Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs.
David V Morrissey, Jennifer A Lockridge, Lucinda Shaw, Karin Blanchard, Kristi Jensen, Keith Bowman

Nat Biotechnol· August 2005

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Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication.
David V Morrissey, Karin Blanchard, Lucinda Shaw, Kristi Jensen, Jennifer A Lockridge, Keith Bowman

Hepatology· June 2005

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