Publications by authors named "Keith Buckler"

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Hif-2α programs oxygen chemosensitivity in chromaffin cells.
Maria Prange-Barczynska, Holly A Jones, Yoichiro Sugimoto, Xiaotong Cheng, Joanna Dcc Lima, Keith J Buckler

J Clin Invest· August 2024

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Lack of influence of dexmedetomidine on rat glomus cell response to hypoxia, and on mouse acute hypoxic ventilatory response.
Peadar B O'Donohoe, Philip J Turner, Nicky Huskens, Keith J Buckler, Jaideep J Pandit

J Anaesthesiol Clin Pharmacol· January 2022

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Competitive Interactions between Halothane and Isoflurane at the Carotid Body and TASK Channels.
Jaideep J Pandit, Nicky Huskens, Peadar B O'Donohoe, Philip J Turner, Keith J Buckler

Anesthesiology· November 2020

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Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control.
Xiaotong Cheng, Maria Prange-Barczynska, James W Fielding, Minghao Zhang, Alana L Burrell, Keith J Buckler

J Clin Invest· May 2020

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Influence of propofol on isolated neonatal rat carotid body glomus cell response to hypoxia and hypercapnia.
Peadar B O'Donohoe, Philip J Turner, Nicky Huskens, Keith J Buckler, Jaideep J Pandit

Respir Physiol Neurobiol· February 2019

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A1899, PK-THPP, ML365, and Doxapram inhibit endogenous TASK channels and excite calcium signaling in carotid body type-1 cells.
Peadar B O'Donohoe, Nicky Huskens, Philip J Turner, Jaideep J Pandit, Keith J Buckler

Physiol Rep· September 2018

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Neurotransmitter Switching Coupled to β-Adrenergic Signaling in Sympathetic Neurons in Prehypertensive States.
Emma N Bardsley, Harvey Davis, Keith J Buckler, David J Paterson

Hypertension· June 2018

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RNA Sequencing Reveals Novel Transcripts from Sympathetic Stellate Ganglia During Cardiac Sympathetic Hyperactivity.
Emma N Bardsley, Harvey Davis, Olujimi A Ajijola, Keith J Buckler, Jeffrey L Ardell

Sci Rep· June 2018

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PHD2 inactivation in Type I cells drives HIF-2α-dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies.
James W Fielding, Emma J Hodson, Xiaotong Cheng, David J P Ferguson, Luise Eckardt, Keith J Buckler

J Physiol· June 2018

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Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway.
Emma J Hodson, Lynn G Nicholls, Philip J Turner, Ronan Llyr, James W Fielding, Keith J Buckler

J Physiol· March 2016

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Functional Properties of Mitochondria in the Type-1 Cell and Their Role in Oxygen Sensing.
Keith J Buckler, Philip J Turner

Adv Exp Med Biol· January 2016

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Moderate inhibition of mitochondrial function augments carotid body hypoxic sensitivity.
Andrew P Holmes, Philip J Turner, Keith J Buckler, Prem Kumar

Pflugers Arch· January 2016

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A method for continuous and stable perfusion of tissue and single cell preparations with accurate concentrations of volatile anaesthetics.
Nicky Huskens, Peadar O'Donohoe, James R Wickens, James S O McCullagh, Keith J Buckler

J Neurosci Methods· January 2016

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TASK channels in arterial chemoreceptors and their role in oxygen and acid sensing.
Keith J Buckler

Pflugers Arch· May 2015

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Glycogen metabolism protects against metabolic insult to preserve carotid body function during glucose deprivation.
Andrew P Holmes, Philip J Turner, Paul Carter, Wendy Leadbeater, Clare J Ray, Keith J Buckler

J Physiol· October 2014

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The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia.
Mary E Slingo, Philip J Turner, Helen C Christian, Keith J Buckler, Peter A Robbins

J Appl Physiol (1985)· April 2014

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Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 and TASK-3 channels in mouse carotid body type-1 cells.
Philip J Turner, Keith J Buckler

J Physiol· December 2013

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Cytosolic calcium regulation in rat afferent vagal neurons during anoxia.
Michael Henrich, Keith J Buckler

Cell Calcium· December 2013

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Oxygen sensitivity of mitochondrial function in rat arterial chemoreceptor cells.
Keith J Buckler, Philip J Turner

J Physiol· July 2013

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Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.
Tammie Bishop, Nick P Talbot, Philip J Turner, Lynn G Nicholls, Alberto Pascual, Keith J Buckler

J Physiol· July 2013

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Responses of glomus cells to hypoxia and acidosis.
Keith J Buckler

J Physiol· July 2013

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Targeted neuronal nitric oxide synthase transgene delivery into stellate neurons reverses impaired intracellular calcium transients in prehypertensive rats.
Dan Li, Natalia Nikiforova, Chieh-Ju Lu, Kate Wannop, Mary McMenamin, Keith J Buckler

Hypertension· January 2013

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Effects of exogenous hydrogen sulphide on calcium signalling, background (TASK) K channel activity and mitochondrial function in chemoreceptor cells.
Keith J Buckler

Pflugers Arch· April 2012

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Abnormal intracellular calcium homeostasis in sympathetic neurons from young prehypertensive rats.
Dan Li, Chee-wan Lee, Keith Buckler, Anant Parekh, Neil Herring

Hypertension· March 2012

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'Hypoxic ventilatory decline' in the intracellular Ca2+ response to sustained isocapnic hypoxia in carotid body glomus cells.
Jaideep J Pandit, Josie Collyer, Keith J Buckler

Adv Exp Med Biol· May 2010

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