Publications by authors named "Keith D Barnes"

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Design and synthesis of novel methoxypyridine-derived gamma-secretase modulators.
Kevin D Rynearson, Ronald N Buckle, R Jason Herr, Nicholas J Mayhew, Xinchao Chen, Keith D Barnes

Bioorg Med Chem· November 2020

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Design, Synthesis, and Preclinical Efficacy of Novel Nonretinoid Antagonists of Retinol-Binding Protein 4 in the Mouse Model of Hepatic Steatosis.
Christopher L Cioffi, Boglarka Racz, Andras Varadi, Emily E Freeman, Michael P Conlon, Keith D Barnes

J Med Chem· June 2019

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Design and synthesis of aminothiazole modulators of the gamma-secretase enzyme.
Kevin D Rynearson, Ronald N Buckle, Keith D Barnes, R Jason Herr, Nicholas J Mayhew

Bioorg Med Chem Lett· August 2016

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Bicyclic [3.3.0]-Octahydrocyclopenta[c]pyrrolo Antagonists of Retinol Binding Protein 4: Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease.
Christopher L Cioffi, Boglarka Racz, Emily E Freeman, Michael P Conlon, Ping Chen, Keith D Barnes

J Med Chem· August 2015

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Design, synthesis, and evaluation of nonretinoid retinol binding protein 4 antagonists for the potential treatment of atrophic age-related macular degeneration and Stargardt disease.
Christopher L Cioffi, Nicoleta Dobri, Emily E Freeman, Michael P Conlon, Ping Chen, Keith D Barnes

J Med Chem· September 2014

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Biaryl purine derivatives as potent antiproliferative agents: inhibitors of cyclin dependent kinases. Part I.
Michael P Trova, Keith D Barnes, Curt Barford, Travis Benanti, Mark Bielaska

Bioorg Med Chem Lett· December 2009

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Heterobiaryl purine derivatives as potent antiproliferative agents: inhibitors of cyclin dependent kinases. Part II.
Michael P Trova, Keith D Barnes, Luis Alicea, Travis Benanti, Mark Bielaska

Bioorg Med Chem Lett· December 2009

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