Publications by authors named "Keith Laderoute"

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5'-AMP-activated protein kinase (AMPK) supports the growth of aggressive experimental human breast cancer tumors.
Keith R Laderoute, Joy M Calaoagan, Wan-Ru Chao, Dominc Dinh, Nicholas Denko

J Biol Chem· August 2014

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Transcriptional regulation of gene expression during osmotic stress responses by the mammalian target of rapamycin.
M Carmen Ortells, Beatriz Morancho, Katherine Drews-Elger, Benoit Viollet, Keith R Laderoute

Nucleic Acids Res· May 2012

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5'-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat.
Taichang Jang, Joy M Calaoagan, Eunice Kwon, Steven Samuelsson, Lawrence Recht, Keith R Laderoute

Int J Cancer· May 2011

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SR16388: a steroidal antiangiogenic agent with potent inhibitory effect on tumor growth in vivo.
Wan-Ru Chao, Khalid Amin, Yihui Shi, Peter Hobbs, Mas Tanabe, Keith Laderoute

Angiogenesis· March 2011

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The rational design of a novel potent analogue of the 5'-AMP-activated protein kinase inhibitor compound C with improved selectivity and cellular activity.
Fouzia Machrouhi, Nouara Ouhamou, Keith Laderoute, Joy Calaoagan, Marina Bukhtiyarova

Bioorg Med Chem Lett· November 2010

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A novel steroidal inhibitor of estrogen-related receptor alpha (ERR alpha).
Sarah J Duellman, Joy M Calaoagan, Barbara G Sato, Richard Fine, Boris Klebansky, Keith R Laderoute

Biochem Pharmacol· September 2010

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SU11248 (sunitinib) directly inhibits the activity of mammalian 5'-AMP-activated protein kinase (AMPK).
Keith R Laderoute, Joy M Calaoagan, Peter B Madrid, Anthony E Klon, Paula J Ehrlich

Cancer Biol Ther· July 2010

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Selective deficiency of HIF-1alpha in myeloid cells influences secondary intention wound healing in mouse skin.
Richard A Owings, Marjan Boerma, Junru Wang, Maaike Berbee, Keith R Laderoute

In Vivo· March 2010

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The metal-responsive transcription factor-1 protein is elevated in human tumors.
Yihui Shi, Khalid Amin, Barbara G Sato, Steven J Samuelsson, Lidia Sambucetti, Keith Laderoute

Cancer Biol Ther· March 2010

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Integrated analysis of breast cancer cell lines reveals unique signaling pathways.
Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp

Genome Biol· July 2009

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A novel peroxisome proliferator-activated receptor delta antagonist, SR13904, has anti-proliferative activity in human cancer cells.
Nurulain T Zaveri, Barbara G Sato, Faming Jiang, Joy Calaoagan, Keith R Laderoute

Cancer Biol Ther· July 2009

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Changes to NIH grant system may backfire.
Peter D Karp, Gavin Sherlock, John A Gerlt, Ida Sim, Ian Paulsen, Keith Laderoute

Science· November 2008

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AMP-activated protein kinase inhibits transforming growth factor-beta-induced Smad3-dependent transcription and myofibroblast transdifferentiation.
Rangnath Mishra, Barbara L Cool, Keith R Laderoute, Marc Foretz, Benoit Viollet

J Biol Chem· April 2008

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The interaction between HIF-1 and AP-1 transcription factors in response to low oxygen.
Keith R Laderoute

Semin Cell Dev Biol· July 2006

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5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments.
Keith R Laderoute, Khalid Amin, Joy M Calaoagan, Merrill Knapp, Theresamai Le

Mol Cell Biol· July 2006

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The metal-responsive transcription factor-1 contributes to HIF-1 activation during hypoxic stress.
Brian J Murphy, Barbara G Sato, Timothy P Dalton, Keith R Laderoute

Biochem Biophys Res Commun· November 2005

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Glucose utilization is essential for hypoxia-inducible factor 1 alpha-dependent phosphorylation of c-Jun.
Keith R Laderoute, Joy M Calaoagan, Merrill Knapp, Randall S Johnson

Mol Cell Biol· May 2004

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Pathway logic: symbolic analysis of biological signaling.
Steven Eker, Merrill Knapp, Keith Laderoute, Patrick Lincoln, Jose Meseguer

Pac Symp Biocomput· October 2002

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The response of c-jun/AP-1 to chronic hypoxia is hypoxia-inducible factor 1 alpha dependent.
Keith R Laderoute, Joy M Calaoagan, Cindy Gustafson-Brown, A Merrill Knapp, Guo-Chun Li

Mol Cell Biol· April 2002

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