Publications by authors named "Keith Ligon"

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Integration of omics data in the diagnosis and therapy of glioblastoma.
Constantin Möller, Melanie Schoof, Keith L Ligon, Ulrich Schüller

Brain Pathol· January 2026

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Contrastive learning enhances fairness in pathology artificial intelligence systems.
Shih-Yen Lin, Pei-Chen Tsai, Fang-Yi Su, Chun-Yen Chen, Fuchen Li, Keith L Ligon

Cell Rep Med· December 2025

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High-throughput single-cell density measurements enable dynamic profiling of immune cell and drug response from patient samples.
Weida Wu, Sarah H Ishamuddin, Thomas W Quinn, Smitha Yerrum, Ye Zhang, Keith L Ligon

Nat Biomed Eng· November 2025

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Cancers modulate p53 truncal neoantigen display to evade T cell detection.
Koji Haratani, Bruce Reinhold, Jonathan S Duke-Cohan, Caroline G Fahey, Kemin Tan, Keith L Ligon

bioRxiv· November 2025

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Clinical, molecular, and radiological predictors of prognosis in newly diagnosed astrocytoma, IDH-mutant, WHO grade 4.
Aleksandra B Lasica, Zhou Lan, Julie J Miller, Albert Jiao, Ian Pan, Keith L Ligon

Neuro Oncol· October 2025

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Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis.
Solomiia Savchuk, Kaylee M Gentry, Wengang Wang, Elana Carleton, Carlos A O Biagi-Junior, Keith L Ligon

Nature· October 2025

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Increased SOX10, p16, and Cyclin D1 Immunoreactivity Differentiates MAP Kinase-activated Low-grade Gliomas From Piloid Gliosis: Erratum.
Vivian Tang, Kevin Y Zhang, Kanish Mirchia, Rufei Lu, Ekin Guney, Azra H Ligon, Keith L Ligon

Am J Surg Pathol· October 2025

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Serial multiomics uncovers anti-glioblastoma responses not evident by routine clinical analyses.
Alexander L Ling, Jennifer Gantchev, Michael C Prabhu, Sreyashi Basu, Ryuhjin Ahn, Keith L Ligon

Sci Transl Med· October 2025

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Author Correction: A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas.
April A Apfelbaum, Eric Morin, Dominik Sturm, Georges Ayoub, Jeromy DiGiacomo, Keith L Ligon

Nat Commun· October 2025

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Preclinical Modeling of Navtemadlin Pharmacokinetics, Pharmacodynamics, and Efficacy in IDH-Wild-type Glioblastoma.
Rachael A Vaubel, Wenjuan Zhang, Ju-Hee Oh, Ann C Mladek, Tugce I Pasa, Keith L Ligon

Clin Cancer Res· September 2025

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Uncertainty-aware ensemble of foundation models differentiates glioblastoma from its mimics.
Junhan Zhao, Shih-Yen Lin, Raphaël Attias, Liza Mathews, Christian Engel, Keith L Ligon

Nat Commun· September 2025

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An oncolytic herpes simplex virus armed with IL-12 for treatment of preclinical glioblastoma.
Joseph W Jackson, Bonnie L Hall, Chaim Sneiderman, Amy Webb, Trevor J Hancock, Keith Ligon

Mol Ther Oncol· September 2025

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Barcoded viral tracing identifies immunosuppressive astrocyte-glioma interactions.
Brian M Andersen, Camilo Faust Akl, Michael A Wheeler, Zhaorong Li, Martin Diebold, Keith L Ligon

Nature· August 2025

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Revisiting an old therapy for new, promising combinations: biology and perspectives of lomustine in glioma treatment.
Charlotte Bellamy, Cynthia Hajal, Keith L Ligon, Mehdi Touat

Neuro Oncol· August 2025

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Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity.
Camilo Faust Akl, Brian M Andersen, Zhaorong Li, Federico Giovannoni, Martin Diebold, Keith L Ligon

Nature· July 2025

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Deep learning volumetrics reveal distinct clinical trajectories for pediatric low-grade gliomas under surveillance: A multicenter study.
Juan Carlos Climent Pardo, Anna Zapaishchykova, Aidan Boyd, Divyanshu Tak, John Zielke, Keith L Ligon

Neurooncol Adv· July 2025

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A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas.
April A Apfelbaum, Eric Morin, Dominik Sturm, Georges Ayoub, Jeromy DiGiacomo, Keith L Ligon

Nat Commun· July 2025

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Inertial sensing of water content in tumor spheroids.
Georgios Katsikis, Jennifer C Yoon, Thomas R Usherwood, Seth Malinowski, Jiaquan Yu, Keith L Ligon

bioRxiv· July 2025

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Dissecting the immune landscape in pediatric high-grade glioma reveals cell state changes under therapeutic pressure.
Jenna J LaBelle, Rebecca D Haase, Alexander Beck, Jacob Haase, Li Jiang, Keith Ligon

Cell Rep Med· May 2025

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The multilayered transcriptional architecture of glioblastoma ecosystems.
Masashi Nomura, Avishay Spitzer, Kevin C Johnson, Luciano Garofano, Djamel Nehar-Belaid, Keith L Ligon

Nat Genet· May 2025

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Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics.
Avishay Spitzer, Kevin C Johnson, Masashi Nomura, Luciano Garofano, Djamel Nehar-Belaid, Keith L Ligon

Nat Genet· May 2025

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Oncogenic drivers shape the tumor microenvironment in human gliomas.
Bo Zhao, Chae Yun Cho, Lingqun Ye, Tula Keal, Thomas Mitchell, Keith L Ligon

bioRxiv· May 2025

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Effective targeting of PDGFRA-altered high-grade glioma with avapritinib.
Lisa Mayr, Sina Neyazi, Kallen Schwark, Maria Trissal, Alexander Beck, Keith Ligon

Cancer Cell· April 2025

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Investigative needle core biopsies support multimodal deep-data generation in glioblastoma.
Kenny K H Yu, Sreyashi Basu, Gerard Baquer, Ryuhjin Ahn, Jennifer Gantchev, Keith L Ligon

Nat Commun· April 2025

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A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma.
Veronica Rendo, Eudocia Q Lee, Connor Bossi, Nicholas Khuu, Michelle A Rudek, Keith L Ligon

Sci Transl Med· February 2025

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