Publications by authors named "Keith P Ray"

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Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease.
Kevin J Roberts, Marion F Cubitt, Timothy M Carlton, Lurdes Rodrigues-Duarte, Luana Maggiore, Ray Chai, Keith P Ray

Sci Rep· September 2021

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Oral Anti-Tumour Necrosis Factor Domain Antibody V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis Patients.
Suhail Nurbhai, Kevin J Roberts, Timothy M Carlton, Luana Maggiore, Marion F Cubitt, Keith P Ray

Sci Rep· October 2019

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Oral delivery of the anti-tumor necrosis factor α domain antibody, V565, results in high intestinal and fecal concentrations with minimal systemic exposure in cynomolgus monkeys.
J Scott Crowe, Kevin J Roberts, Timothy M Carlton, Luana Maggiore, Marion F Cubitt, Keith P Ray

Drug Dev Ind Pharm· March 2019

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Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease.
J Scott Crowe, Kevin J Roberts, Timothy M Carlton, Luana Maggiore, Marion F Cubitt, Keith P Ray

Sci Rep· March 2018

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Inhibitors of p38 suppress cytokine production in rheumatoid arthritis synovial membranes: does variable inhibition of interleukin-6 production limit effectiveness in vivo?
Theresa H Page, Anthony Brown, Emma M Timms, Brian M J Foxwell, Keith P Ray

Arthritis Rheum· November 2010

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Targeting IKKβ for the treatment of rheumatoid arthritis.
Paul Bamborough, Mary A Morse, Keith P Ray

Drug News Perspect· October 2010

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Nonsteroidal anti-inflammatory drugs increase TNF production in rheumatoid synovial membrane cultures and whole blood.
Theresa H Page, Jeremy J O Turner, Anthony C Brown, Emma M Timms, Julia J Inglis, Keith P Ray

J Immunol· September 2010

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IkappaB kinase epsilon interacts with p52 and promotes transactivation via p65.
Claudia Wietek, Catherine S Cleaver, Valerie Ludbrook, Jonathan Wilde, Julia White, Keith P Ray

J Biol Chem· November 2006

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Effects of dexamethasone on TNF-alpha-induced release of cytokines from purified human blood eosinophils.
Iain Uings, Ilaria Puxeddu, Vladislav Temkin, Susan J Smith, Dilniya Fattah, Keith P Ray

Clin Mol Allergy· April 2005

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Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling.
Alexander N R Weber, Servane Tauszig-Delamasure, Jules A Hoffmann, Eric Lelièvre, Hugues Gascan, Keith P Ray

Nat Immunol· August 2003

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