Publications by authors named "Keith R Loeb"

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CD74 is expressed in a subset of pediatric acute myeloid leukemia patients and is a promising target for therapy: a report from the Children's Oncology Group.
Andrew J Menssen, Chad A Hudson, Todd Alonzo, Robert Gerbing, Laura Pardo, Keith R Loeb

Haematologica· October 2024

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CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target.
Quy Le, Brandon Hadland, Jenny L Smith, Amanda Leonti, Benjamin J Huang, Anisha M Loeb, Keith R Loeb

J Clin Invest· August 2024

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Donor bone marrow-derived macrophage engraftment into the central nervous system of patients following allogeneic transplantation.
Anisha M Loeb, Siobhan S Pattwell, Soheil Meshinchi, Antonio Bedalov, Keith R Loeb

Blood Adv· October 2023

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Cytokine release syndrome after bronchoalveolar lavage.
Margaret Guerriero, Feras Ally, Keith R Loeb, Viswam S Nair

BMC Pulm Med· October 2023

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Preclinical studies targeting CD74 with STRO-001 antibody-drug conjugate in acute leukemia.
Quy Le, Thao Tang, Amanda Leonti, Sommer Castro, Cyd Nourigat McKay, Keith R Loeb

Blood Adv· May 2023

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Therapeutic targeting of PRAME with mTCRCAR T cells in acute myeloid leukemia.
Danielle C Kirkey, Anisha M Loeb, Sommer Castro, Cyd Nourigat McKay, LaKeisha Perkins, Keith R Loeb

Blood Adv· April 2023

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CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target.
Quy Le, Brandon Hadland, Jenny L Smith, Amanda Leonti, Benjamin J Huang, Anisha M Loeb, Keith R Loeb

J Clin Invest· November 2022

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Targeting FOLR1 in high-risk CBF2AT3-GLIS2 pediatric AML with STRO-002 FOLR1-antibody-drug conjugate.
Thao Tang, Quy Le, Sommer Castro, Laura Pardo, Cyd Nourigat McKay, Keith R Loeb

Blood Adv· November 2022

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Oncogenic role of a developmentally regulated splice variant.
Siobhan S Pattwell, Sonali Arora, Nicholas Nuechterlein, Michael Zager, Keith R Loeb

Sci Adv· October 2022

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Transcutaneous ultrasound-mediated gene delivery into canine livers achieves therapeutic levels of factor VIII expression.
Megan A Manson, Feng Zhang, Alexander Novokhodko, Chun-Yu Chen, Maura Parker, Keith R Loeb

Blood Adv· June 2022

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Accurate detection of subclonal variants in paired diagnosis-relapse acute myeloid leukemia samples by next generation Duplex Sequencing.
Ashwini S Kamath-Loeb, Jiang-Cheng Shen, Michael W Schmitt, Brendan F Kohrn, Keith R Loeb, Lawrence A Loeb

Leuk Res· April 2022

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FOXM1 drives HPV+ HNSCC sensitivity to WEE1 inhibition.
Ahmed Diab, Hakan Gem, Jherek Swanger, Hee Yeon Kim, Kaleb Smith, Keith R Loeb

Proc Natl Acad Sci U S A· November 2020

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Targeted Sequencing Improves DIPSS-Plus Prognostic Scoring in Myelofibrosis Patients Undergoing Allogeneic Transplantation.
Emily A Stevens, Isaac C Jenkins, Lan W Beppu, Qing Zhang, Rachel Salit, Keith R Loeb

Biol Blood Marrow Transplant· July 2020

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Comprehensive Transcriptome Profiling of Cryptic Fusion-Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study.
Jenny L Smith, Rhonda E Ries, Tiffany Hylkema, Todd A Alonzo, Robert B Gerbing, Keith R Loeb

Clin Cancer Res· February 2020

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A high-resolution landscape of mutations in the super-enhancer in normal human B cells.
Jiang-Cheng Shen, Ashwini S Kamath-Loeb, Brendan F Kohrn, Keith R Loeb, Bradley D Preston, Lawrence A Loeb

Proc Natl Acad Sci U S A· December 2019

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Transcutaneous Ultrasound-Mediated Nonviral Gene Delivery to the Liver in a Porcine Model.
Dominic M Tran, Feng Zhang, Kyle P Morrison, Keith R Loeb, James Harrang

Mol Ther Methods Clin Dev· September 2019

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Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice.
Keith R Loeb, Bridget T Hughes, Brian M Fissel, Nyka J Osteen, Sue E Knoblaugh

Sci Rep· April 2019

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Whole-genome sequencing of esophageal adenocarcinoma in Chinese patients reveals distinct mutational signatures and genomic alterations.
James Y Dai, Xiaoyu Wang, Matthew F Buas, Chengjuan Zhang, Jie Ma, Keith R Loeb

Commun Biol· October 2018

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Ultrasound-Mediated Gene Therapy in Swine Livers Using Single-Element, Multi-lensed, High-Intensity Ultrasound Transducers.
Misty L Noble-Vranish, Shuxian Song, Kyle P Morrison, Dominic M Tran, Ryan R Sun, Keith R Loeb

Mol Ther Methods Clin Dev· September 2018

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Pilot study of lithium to restore intestinal barrier function in severe graft-versus-host disease.
Gideon Steinbach, David M Hockenbery, Gerwin Huls, Terry Furlong, David Myerson, Keith R Loeb

PLoS One· October 2017

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Massively parallel digital transcriptional profiling of single cells.
Grace X Y Zheng, Jessica M Terry, Phillip Belgrader, Paul Ryvkin, Zachary W Bent, Keith R Loeb

Nat Commun· January 2017

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Comparative analysis of flow cytometry and morphology for the detection of acute myeloid leukaemia cells in cerebrospinal fluid.
Keith R Loeb, Sindhu Cherian, Pamela S Becker, Roland B Walter, John M Pagel

Br J Haematol· January 2016

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Outcomes of acute leukemia patients transplanted with naive T cell-depleted stem cell grafts.
Marie Bleakley, Shelly Heimfeld, Keith R Loeb, Lori A Jones, Colette Chaney

J Clin Invest· July 2015

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Central nervous system involvement in acute myeloid leukemia patients undergoing hematopoietic cell transplantation.
Merav Bar, Weigang Tong, Megan Othus, Keith R Loeb, Elihu H Estey

Biol Blood Marrow Transplant· March 2015

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Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy.
Michael Y Zhang, Jane E Churpek, Siobán B Keel, Tom Walsh, Ming K Lee, Keith R Loeb

Nat Genet· February 2015

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