Publications by authors named "Michael Zager"

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Molecular profiling of adult C. elegans glia across sexes by single-nuclear RNA-seq.
Maria D Purice, Elgene J A Quitevis, R Sean Manning, Liza J Severs, Nina-Tuyen Tran, Michael Zager

Dev Cell· October 2025

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A kinase to cytokine explorer to identify molecular regulators and potential therapeutic opportunities.
Marina Chan, Yuqi Kang, Shannon Osborne, Michael Zager, Taranjit S Gujral

Elife· February 2024

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Defining cellular population dynamics at single-cell resolution during prostate cancer progression.
Alexandre A Germanos, Sonali Arora, Ye Zheng, Erica T Goddard, Ilsa M Coleman, Michael Zager

Elife· December 2022

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Sources of inter-individual variability leading to significant changes in anti-PD-1 and anti-PD-L1 efficacy identified in mouse tumor models using a QSP framework.
Jessica C Leete, Michael G Zager, Cynthia J Musante, Blerta Shtylla, Wenlian Qiao

Front Pharmacol· December 2022

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Oncogenic role of a developmentally regulated splice variant.
Siobhan S Pattwell, Sonali Arora, Nicholas Nuechterlein, Michael Zager, Keith R Loeb

Sci Adv· October 2022

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Model-informed drug development of voxelotor in sickle cell disease: Population pharmacokinetics in whole blood and plasma.
Radojka M Savic, Michelle L Green, Karin Jorga, Michael Zager, Carla B Washington

CPT Pharmacometrics Syst Pharmacol· June 2022

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Single-cell immunology of SARS-CoV-2 infection.
Yuan Tian, Lindsay N Carpp, Helen E R Miller, Michael Zager, Evan W Newell

Nat Biotechnol· January 2022

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Integrated analysis of multimodal single-cell data.
Yuhan Hao, Stephanie Hao, Erica Andersen-Nissen, William M Mauck, Shiwei Zheng, Michael Zager

Cell· June 2021

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Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19.
Yapeng Su, Daniel Chen, Dan Yuan, Christopher Lausted, Jongchan Choi, Michael A Zager

Cell· December 2020

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A human cell atlas of fetal chromatin accessibility.
Silvia Domcke, Andrew J Hill, Riza M Daza, Junyue Cao, Diana R O'Day, Michael A Zager

Science· November 2020

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A human cell atlas of fetal gene expression.
Junyue Cao, Diana R O'Day, Hannah A Pliner, Paul D Kingsley, Mei Deng, Michael A Zager

Science· November 2020

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Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories.
Yapeng Su, Daniel Chen, Christopher Lausted, Dan Yuan, Jongchan Choi, Zager A Michael

bioRxiv· July 2020

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Analysis and visualization of linked molecular and clinical cancer data by using Oncoscape.
Lisa G McFerrin, Michael Zager, Jianan Zhang, Gretchen Krenn, Robert McDermott

Nat Genet· September 2018

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Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery.
Patrick J Cimino, Michael Zager, Lisa McFerrin, Hans-Georg Wirsching, Hamid Bolouri

Acta Neuropathol Commun· May 2017

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Chemogenetic evaluation of the mitotic kinesin CENP-E reveals a critical role in triple-negative breast cancer.
Pei-Pei Kung, Ricardo Martinez, Zhou Zhu, Michael Zager, Alessandra Blasina

Mol Cancer Ther· August 2014

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Preclinical PK/PD modeling and human efficacious dose projection for a glucokinase activator in the treatment of diabetes.
Michael G Zager, Kirk Kozminski, Bernadette Pascual, Kathleen M Ogilvie, Shaoxian Sun

J Pharmacokinet Pharmacodyn· April 2014

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The development of a fully-integrated immune response model (FIRM) simulator of the immune response through integration of multiple subset models.
Sirus Palsson, Timothy P Hickling, Erica L Bradshaw-Pierce, Michael Zager, Karin Jooss

BMC Syst Biol· September 2013

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A multiscale, mechanism-driven, dynamic model for the effects of 5α-reductase inhibition on prostate maintenance.
Michael G Zager, Hugh A Barton

PLoS One· May 2013

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Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth.
Brion W Murray, Chuangxing Guo, Joseph Piraino, John K Westwick, Cathy Zhang, Michael Zager

Proc Natl Acad Sci U S A· May 2010

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A delayed nonlinear PBPK model for genistein dosimetry in rats.
Michael G Zager, Paul M Schlosser, Hien T Tran

Bull Math Biol· January 2007

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Mathematical model for the androgenic regulation of the prostate in intact and castrated adult male rats.
Laura K Potter, Michael G Zager, Hugh A Barton

Am J Physiol Endocrinol Metab· November 2006

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