Publications by authors named "Keith Walley"

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Obesity- and Lipid-Related Traits May Causally Contribute to Sepsis-Associated Acute Kidney Injury.
Kyle R Campbell, Nozomi Takahashi, Tadanaga Shimada, Taka-Aki Nakada, James A Russell, Keith R Walley

Crit Care Med· November 2025

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Decreased Clearance of Low-Density Lipoprotein Cholesterol is Causally Associated With Increased Mortality of Septic Shock.
Nozomi Takahashi, Kyle R Campbell, Taka-Aki Nakada, Keith R Walley

Crit Care Med· October 2025

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Plasma apolipoprotein A-I is a causal protective factor in sepsis.
Kyle R Campbell, Kantimas Sitthikool, Kelly Roveran Genga, Nozomi Takahashi, Gary Zhu, Keith R Walley

Sci Rep· September 2025

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Machine Learning Accurately Predicts Need for Critical Care Support in Patients Admitted to Hospital for Community-Acquired Pneumonia.
George S Chen, Terry Lee, Jennifer L Y Tsang, Alexandra Binnie, Anne McCarthy, Keith R Walley

Crit Care Explor· June 2025

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Low apolipoprotein A-II levels causally contribute to increased mortality in septic shock.
Nozomi Takahashi, Kyle R Campbell, Tadanaga Shimada, Taka-Aki Nakada, James A Russell, Keith R Walley

J Intensive Care· February 2025

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Complex Thrombo-Inflammatory Responses versus Outcomes of Non-COVID-19 Community-Acquired Pneumonia and COVID-19.
Greg Haljan, Terry Lee, Anne McCarthy, Juthaporn Cowan, Jennifer Tsang, Keith R Walley

J Innate Immun· December 2024

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Community versus academic hospital community-acquired pneumonia patients: a nested cohort study.
Jennifer L Y Tsang, Kian Rego, Alexandra Binnie, Terry Lee, Anne Mccarthy, Keith R Walley

Pneumonia (Nathan)· November 2024

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Cardiovascular risk and subclinical atherosclerosis in first-degree relatives of patients with premature cardiovascular disease.
Diana N Vikulova, Danielle Pinheiro-Muller, Gordon Francis, Frank Halperin, Tara Sedlak, Keith Walley

Am J Prev Cardiol· September 2024

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Effects of Losartan on Patients Hospitalized for Acute COVID-19: A Randomized Controlled Trial.
Karen C Tran, Pierre Asfar, Matthew Cheng, Julien Demiselle, Joel Singer, Keith Walley

Clin Infect Dis· September 2024

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Lessons From the LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P) Trial.
Keith R Walley

Crit Care Med· August 2024

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Efficacy and Safety of Umbilical Cord-Derived Mesenchymal Stromal Cell Therapy in Preclinical Models of Sepsis: A Systematic Review and Meta-analysis.
Christine Hum, Usama Tahir, Shirley H J Mei, Josee Champagne, Dean A Fergusson, Keith Walley

Stem Cells Transl Med· April 2024

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CETP inhibition enhances monocyte activation and bacterial clearance and reduces streptococcus pneumonia-associated mortality in mice.
Haoyu Deng, Wan Yi Liang, Le Qi Chen, Tin Ho Yuen, Basak Sahin, Keith Walley

JCI Insight· April 2024

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Using a targeted metabolomics approach to explore differences in ARDS associated with COVID-19 compared to ARDS caused by H1N1 influenza and bacterial pneumonia.
Chel Hee Lee, Mohammad M Banoei, Mariam Ansari, Matthew P Cheng, Francois Lamontagne, Keith R Walley

Crit Care· February 2024

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Proteomic Evolution from Acute to Post-COVID-19 Conditions.
Yassene Mohammed, Karen Tran, Chris Carlsten, Christopher Ryerson, Alyson Wong, Keith R Walley

J Proteome Res· January 2024

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Identifying molecular phenotypes in sepsis: an analysis of two prospective observational cohorts and secondary analysis of two randomised controlled trials.
Pratik Sinha, V Eric Kerchberger, Andrew Willmore, Julia Chambers, Hanjing Zhuo, Keith R Walley

Lancet Respir Med· November 2023

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Pharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival From Sepsis.
Patrick R Lawler, Garen Manvelian, Alida Coppi, Amy Damask, Michael N Cantor, Keith R Walley

Crit Care Explor· November 2023

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Metabolomics Analysis of Mesenchymal Stem Cell (MSC) Therapy in a Phase I Clinical Trial of Septic Shock: An Exploratory Study.
Mohammad M Banoei, Lauralyn A McIntyre, Duncan J Stewart, Shirley H J Mei, David Courtman, Keith R Walley

Metabolites· November 2023

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Impact of the COVID-19 pandemic on non-COVID-19 community-acquired pneumonia: a retrospective cohort study.
Terry Lee, Keith R Walley, John H Boyd, Kelly A Cawcutt, Andre Kalil

BMJ Open Respir Res· October 2023

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Outcomes and characteristics of patients hospitalized for COVID-19 in British Columbia, Ontario and Quebec during the Omicron wave.
Terry Lee, Matthew P Cheng, Donald C Vinh, Todd C Lee, Karen C Tran, Keith R Walley

CMAJ Open· August 2023

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Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1.
Mihir R Atreya, Natalie Z Cvijanovich, Julie C Fitzgerald, Scott L Weiss, Michael T Bigham, Keith R Walley

Crit Care· June 2023

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Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1.
Mihir R Atreya, Natalie Z Cvijanovich, Julie C Fitzgerald, Scott L Weiss, Michael T Bigham, Keith R Walley

Res Sq· February 2023

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Modulation of vascular endothelial inflammatory response by proprotein convertase subtilisin-kexin type 9.
Alex K K Leung, Yuan Chao Xue, Antyrah de Guzman, Guilherme Grzelkovski, HyeJin Julia Kong, Keith R Walley

Atherosclerosis· December 2022

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Use of Mendelian randomization to better understand and treat sepsis.
James A Russell, Nuala J Meyer, Keith R Walley

Intensive Care Med· November 2022

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Welfare issues and potential solutions for laying hens in free range and organic production systems: A review based on literature and interviews.
Claire Bonnefous, Anne Collin, Laurence A Guilloteau, Vanessa Guesdon, Christine Filliat, Keith Walley

Front Vet Sci· August 2022

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Redefining critical illness.
David M Maslove, Benjamin Tang, Manu Shankar-Hari, Patrick R Lawler, Derek C Angus, Keith R Walley

Nat Med· June 2022

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