Publications by authors named "Kellen Winden"

Claim this Profile
N
Neuronal hyperactivity becomes mTORC1 independent due to transcriptional changes in tuberous sclerosis complex disease models.
Wardiya Afshar-Saber, Juan F Ruiz, Isabel Gisser, Ziqin Yang, Leena Mehendale, Kellen D Winden

Cell Rep· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phenotypic rescue via mTOR inhibition in neuron-specific Pten knockout mice reveals AKT and mTORC1-site specific changes.
Angelica D'Amore, Maria Sundberg, Rui Lin, Ella T Lubbers, Kellen D Winden

Mol Psychiatry· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An open-source pipeline for calcium imaging and all-optical physiology in human stem cell-derived neurons.
Wardiya Afshar-Saber, Federico M Gasparoli, Ziqin Yang, Nicole A Teaney, Lahin Lalani, Kellen D Winden

bioRxiv· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors.
Tyrone DeSpenza, Emre Kiziltug, Garrett Allington, Daniel G Barson, Stephen McGee, Kellen Winden

Nat Neurosci· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Construction destruction: Contribution of dyregulated proteostasis to neurodevelopmental disorders.
Kellen D Winden, Juan F Ruiz, Mustafa Sahin

Curr Opin Neurobiol· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Using cortical organoids to understand the pathogenesis of malformations of cortical development.
Kellen D Winden, Isabel Gisser, Mustafa Sahin

Front Neurosci· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
ALDH5A1-deficient iPSC-derived excitatory and inhibitory neurons display cell type specific alterations.
Wardiya Afshar-Saber, Nicole A Teaney, Kellen D Winden, Hellen Jumo, Xutong Shi

Neurobiol Dis· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia.
Afshin Saffari, Barbara Brechmann, Cedric Böger, Wardiya Afshar Saber, Hellen Jumo, Kellen Winden

Nat Commun· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Increased degradation of FMRP contributes to neuronal hyperexcitability in tuberous sclerosis complex.
Kellen D Winden, Truc T Pham, Nicole A Teaney, Juan Ruiz, Ryan Chen

Cell Rep· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High-Content Small Molecule Screen Identifies a Novel Compound That Restores AP-4-Dependent Protein Trafficking in Neuronal Models of AP-4-Associated Hereditary Spastic Paraplegia.
Afshin Saffari, Barbara Brechmann, Cedric Boeger, Wardiya Afshar Saber, Hellen Jumo, Kellen Winden

Res Sq· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
1
16p13.11 deletion variants associated with neuropsychiatric disorders cause morphological and synaptic changes in induced pluripotent stem cell-derived neurons.
Elizabeth D Buttermore, Nickesha C Anderson, Pin-Fang Chen, Nina R Makhortova, Kristina H Kim, Kellen D Winden

Front Psychiatry· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Translating Ribosome Affinity Purification (TRAP) of Cell Type-specific mRNA from Mouse Brain Lysates.
Catherine L Salussolia, Kellen D Winden, Mustafa Sahin

Bio Protoc· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Arthritis flares mediated by tissue-resident memory T cells in the joint.
Margaret H Chang, Anaïs Levescot, Nathan Nelson-Maney, Rachel B Blaustein, Kellen D Winden

Cell Rep· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts.
Jasbir Singh Dalal, Kellen Diamond Winden, Catherine Lourdes Salussolia, Maria Sundberg, Achint Singh

Elife· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
1
16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro.
Maria Sundberg, Hannah Pinson, Richard S Smith, Kellen D Winden, Pooja Venugopal

Nat Commun· May 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile.
Krinio Giannikou, Zachary Zhu, Jaegil Kim, Kellen D Winden, Magdalena E Tyburczy

Mod Pathol· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia.
Alessia Di Nardo, Isadora Lenoël, Kellen D Winden, Alina Rühmkorf, Meera E Modi

Cell Rep· June 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biallelic Mutations in Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons.
Kellen D Winden, Maria Sundberg, Cindy Yang, Syed M A Wafa, Sean Dwyer

J Neurosci· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin.
Maria Sundberg, Ivan Tochitsky, David E Buchholz, Kellen Winden, Ville Kujala

Mol Psychiatry· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Abnormal mTOR Activation in Autism.
Kellen D Winden, Darius Ebrahimi-Fakhari, Mustafa Sahin

Annu Rev Neurosci· July 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex.
Ebru Ercan, Juliette M Han, Alessia Di Nardo, Kellen Winden, Min-Joon Han

J Exp Med· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy.
Mary H Wertz, Kellen Winden, Pierre Neveu, Shi-Yan Ng, Ebru Ercan

Hum Mol Genet· June 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular alterations in areas generating fast ripples in an animal model of temporal lobe epilepsy.
Kellen D Winden, Anatol Bragin, Jerome Engel, Dan H Geschwind

Neurobiol Dis· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Megalencephaly and Macrocephaly.
Kellen D Winden, Christopher J Yuskaitis, Annapurna Poduri

Semin Neurol· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Stroke in primary hyperoxaluria type I.
Neal M Rao, Anil Yallapragada, Kellen D Winden, Jeffrey Saver, David S Liebeskind

J Neuroimaging· April 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis