Publications by authors named "Kelly D Sullivan"

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An integrated multi-omic natural history study of human development, sexual dimorphism, and the effects of trisomy 21.
Neetha Paul Eduthan, Micah G Donovan, Paula Araya, Angela L Rachubinski, Kelly D Sullivan

Nat Commun· September 2025

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Interferon signaling modulates Down syndrome-associated Alzheimer's disease pathology in a mouse model.
Paula Araya, Brian Niemeyer, Kyndal Schade, Lauren N Dunn, Katherine Waugh, Kelly D Sullivan

iScience· August 2025

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Altered Hepatic Metabolism in Down Syndrome.
Lauren N Dunn, Brian F Niemeyer, Neetha P Eduthan, Kyndal A Schade, Katherine A Waugh, Kelly D Sullivan

bioRxiv· May 2025

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NF-κB signaling directs a program of transient amplifications at innate immune response genes.
Michael P Ludwig, Jason R Wilson, Matthew D Galbraith, Nirajan Bhandari, Lauren N Dunn, Kelly D Sullivan

bioRxiv· March 2025

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Integrated analysis of immunometabolic interactions in Down syndrome.
Lucas A Gillenwater, Matthew D Galbraith, Angela L Rachubinski, Neetha Paul Eduthan, Kelly D Sullivan

Sci Adv· December 2024

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JAK inhibition decreases the autoimmune burden in Down syndrome.
Angela L Rachubinski, Elizabeth Wallace, Emily Gurnee, Belinda A Enriquez-Estrada, Kayleigh R Worek, Kelly D Sullivan

Elife· December 2024

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JAK inhibition decreases the autoimmune burden in Down syndrome.
Angela L Rachubinski, Elizabeth Wallace, Emily Gurnee, Belinda A Enriquez Estrada, Kayleigh R Worek, Kelly D Sullivan

medRxiv· October 2024

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Multimodal analysis of dysregulated heme metabolism, hypoxic signaling, and stress erythropoiesis in Down syndrome.
Micah G Donovan, Angela L Rachubinski, Keith P Smith, Paula Araya, Katherine A Waugh, Kelly D Sullivan

Cell Rep· August 2024

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Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome.
Micah G Donovan, Neetha P Eduthan, Keith P Smith, Eleanor C Britton, Hannah R Lyford, Kelly D Sullivan

Nat Commun· June 2024

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Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells.
Samantha J Linder, Tiziano Bernasocchi, Bárbara Martínez-Pastor, Kelly D Sullivan, Matthew D Galbraith

Nat Metab· December 2023

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Proteasome Inhibition Sensitizes Liposarcoma to MDM2 Inhibition with Nutlin-3 by Activating the ATF4/CHOP Stress Response Pathway.
Michael P Ludwig, Matthew D Galbraith, Neetha Paul Eduthan, Amanda A Hill, Michael R Clay, Kelly D Sullivan

Cancer Res· August 2023

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Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection.
Samantha N Thomas, Brian F Niemeyer, Rocio J Jimenez-Valdes, Alexander J Kaiser, Joaquin M Espinosa, Kelly D Sullivan

iScience· August 2023

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Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model.
Katherine A Waugh, Ross Minter, Jessica Baxter, Congwu Chi, Matthew D Galbraith, Kelly D Sullivan

Nat Genet· June 2023

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Multidimensional definition of the interferonopathy of Down syndrome and its response to JAK inhibition.
Matthew D Galbraith, Angela L Rachubinski, Keith P Smith, Paula Araya, Katherine A Waugh, Kelly D Sullivan

Sci Adv· June 2023

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FAM193A is a positive regulator of p53 activity.
Maria M Szwarc, Anna L Guarnieri, Molishree Joshi, Huy N Duc, Madison C Laird, Kelly D Sullivan

Cell Rep· March 2023

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Trisomy 21 induces pericentrosomal crowding delaying primary ciliogenesis and mouse cerebellar development.
Cayla E Jewett, Bailey L McCurdy, Eileen T O'Toole, Alexander J Stemm-Wolf, Katherine S Given, Kelly D Sullivan

Elife· January 2023

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PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response.
Zdenek Andrysik, Kelly D Sullivan, Jeffrey S Kieft, Joaquin M Espinosa

Nat Commun· December 2022

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IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome.
Paula Araya, Kohl T Kinning, Christina Coughlan, Keith P Smith, Ross E Granrath, Kelly D Sullivan

Cell Rep· December 2022

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A novel PLK1 inhibitor onvansertib effectively sensitizes MYC-driven medulloblastoma to radiotherapy.
Dong Wang, Bethany Veo, Angela Pierce, Susan Fosmire, Krishna Madhavan, Kelly D Sullivan

Neuro Oncol· March 2022

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Specialized interferon action in COVID-19.
Matthew D Galbraith, Kohl T Kinning, Kelly D Sullivan, Paula Araya, Keith P Smith

Proc Natl Acad Sci U S A· March 2022

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The COVIDome Explorer researcher portal.
Kelly Daniel Sullivan, Matthew Dominic Galbraith, Kohl Thomas Kinning, Kyle William Bartsch, Nik Caldwell Levinsky

Cell Rep· August 2021

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Global Analyses to Identify Direct Transcriptional Targets of p53.
Matthew D Galbraith, Zdenek Andrysik, Kelly D Sullivan, Joaquín M Espinosa

Methods Mol Biol· June 2021

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Precocious clonal hematopoiesis in Down syndrome is accompanied by immune dysregulation.
L Alexander Liggett, Matthew D Galbraith, Keith P Smith, Kelly D Sullivan, Ross E Granrath

Blood Adv· April 2021

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Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma.
Bethany Veo, Etienne Danis, Angela Pierce, Dong Wang, Susan Fosmire, Kelly D Sullivan

Cell Rep· April 2021

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The COVIDome Explorer Researcher Portal.
Kelly D Sullivan, Matthew D Galbraith, Kohl T Kinning, Kyle Bartsch, Nik Levinsky

medRxiv· March 2021

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