Publications by authors named "Kelly Gavin"

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HIF-1α-mediated feedback prevents TOR signalling from depleting oxygen supply and triggering stress during normal development.
Yifan Zhao, Cyrille Alexandre, Gavin Kelly, Jean-Paul Vincent, Gantas Perez-Mockus

Nat Commun· December 2025

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Cholesterol Pathway Gene Variants and Reduced Keratinocyte Cholesterol Support a Final Common Druggable Pathway in Hyperproliferative Inflammatory Skin Diseases.
Melissa Riachi, Dale Bryant, James Ellis, Connor Hughes, Satyamaanasa Polubothu, Gavin Kelly

J Invest Dermatol· November 2025

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Can screening and referral for posttraumatic stress improve mental health and substance abuse service delivery at trauma centers? Results from a randomized trial.
Matthew Iles-Shih, Gavin Kelly, Megan McManamen, Allison Engstrom Buggaveeti, Eileen Bulger

Injury· October 2025

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Evaluation of Hepatitis B core-related antigen (HBcrAg) as a biomarker in cohorts from the United Kingdom and South Africa.
Louise O Downs, Marion Delphin, Marije van Schalkwyk, Susan Hugo, Sheila F Lumley, Gavin Kelly

J Infect· September 2025

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Third exposure to COVID-19 infection or vaccination differentially impacts T cell responses.
Gift Ahimbisibwe, David Greenwood, Katalin Andrea Wilkinson, Joshua Gahir, Hermaleigh Townsley, Gavin Kelly

J Infect· September 2025

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Systematic genetic perturbation reveals principles underpinning robustness of the epigenetic regulatory network.
Thomas Stuart Wilson, Roberta Noberini, Eirini Moysidou, Ifeyinwa Ojukwu, Marta Milan, Gavin Kelly

Nucleic Acids Res· April 2025

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Real-time estimation of immunological responses against emerging SARS-CoV-2 variants in the UK: a mathematical modelling study.
Timothy W Russell, Hermaleigh Townsley, Joel Hellewell, Joshua Gahir, Marianne Shawe-Taylor, Gavin Kelly

Lancet Infect Dis· January 2025

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Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer.
Piyali Ganguli, Celia C Basanta, Amelia Acha-Sagredo, Hrvoje Misetic, Maria Armero, Gavin Kelly

Nat Cancer· January 2025

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Spatial multiplex analysis of lung cancer reveals that regulatory T cells attenuate KRAS-G12C inhibitor-induced immune responses.
Megan Cole, Panayiotis Anastasiou, Claudia Lee, Xiaofei Yu, Andrea de Castro, Gavin Kelly

Sci Adv· November 2024

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Human VCP mutant ALS/FTD microglia display immune and lysosomal phenotypes independently of GPNMB.
Benjamin E Clarke, Oliver J Ziff, Giulia Tyzack, Marija Petrić Howe, Yiran Wang, Gavin Kelly

Mol Neurodegener· November 2024

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Loss of ARID3A perturbs intestinal epithelial proliferation-differentiation ratio and regeneration.
Nikolaos Angelis, Anna Baulies, Florian Hubl, Anna Kucharska, Gavin Kelly

J Exp Med· October 2024

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Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response.
Rebecca A Jones, Fay Cooper, Gavin Kelly, David Barry, Matthew J Renshaw

Open Biol· October 2024

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Chronogram: an R package for data curation and analysis of infection and vaccination cohort studies.
David Greenwood, Marianne Shawe-Taylor, Hermaleigh Townsley, Joshua Gahir, Nikita Sahadeo, Gavin Kelly

Bioinform Adv· September 2024

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Retrospective analysis of hospital electronic health records reveals unseen cases of acute hepatitis with unknown aetiology in adults in Oxfordshire.
Cedric C S Tan, Gavin Kelly, Jack Cregan, Joseph D Wilson, Tim James

BMC Public Health· July 2024

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Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Gavin Kelly

Nat Commun· June 2024

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Vitamin D regulates microbiome-dependent cancer immunity.
Evangelos Giampazolias, Mariana Pereira da Costa, Khiem C Lam, Kok Haw Jonathan Lim, Ana Cardoso, Gavin Kelly

Science· April 2024

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Mosaic BRAF Fusions Are a Recurrent Cause of Congenital Melanocytic Nevi Targetable by MAPK Pathway Inhibition.
Sara Barberan Martin, Satyamaanasa Polubothu, Alicia Lopez Bruzos, Gavin Kelly, Stuart Horswell

J Invest Dermatol· March 2024

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COVID-19 in non-hospitalised adults caused by either SARS-CoV-2 sub-variants Omicron BA.1, BA.2, BA.4/5 or Delta associates with similar illness duration, symptom severity and viral kinetics, irrespective of vaccination history.
Hermaleigh Townsley, Joshua Gahir, Timothy W Russell, David Greenwood, Edward J Carr, Gavin Kelly

PLoS One· March 2024

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SARS-CoV-2 mucosal neutralising immunity after vaccination.
Edward J Carr, Guilia Dowgier, David Greenwood, Lou S Herman, Agnieszka Hobbs, Gavin Kelly

Lancet Infect Dis· January 2024

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Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition.
Oliver J Ziff, Jasmine Harley, Yiran Wang, Jacob Neeves, Giulia Tyzack, Gavin Kelly

Neuron· October 2023

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Healthcare Worker Characteristics Associated with SARS-CoV-2 Vaccine Uptake in Ireland; a Multicentre Cross-Sectional Study.
Liam Townsend, Gavin Kelly, Claire Kenny, Jonathan McGrath, Seán Donohue

Vaccines (Basel)· September 2023

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Neutralising immunity to omicron sublineages BQ.1.1, XBB, and XBB.1.5 in healthy adults is boosted by bivalent BA.1-containing mRNA vaccination and previous Omicron infection.
Edward J Carr, Mary Y Wu, Joshua Gahir, Ruth Harvey, Hermaleigh Townsley, Gavin Kelly

Lancet Infect Dis· July 2023

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Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer.
Mary Y Wu, Scott T C Shepherd, Annika Fendler, Edward J Carr, Lewis Au, Gavin Kelly

Cancer Cell· May 2023

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Corrigendum: Improved memory CD8 T cell response to delayed vaccine boost is associated with a distinct molecular signature.
Ambra Natalini, Sonia Simonetti, Gabriele Favaretto, Lorenzo Lucantonio, Giovanna Peruzzi, Gavin Kelly

Front Immunol· May 2023

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Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology.
Oliver J Ziff, Jacob Neeves, Jamie Mitchell, Giulia Tyzack, Carlos Martinez-Ruiz, Gavin Kelly

Nat Commun· April 2023

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