Publications by authors named "Sebastijan Hobor"

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Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell

Nat Commun· June 2024

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Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution.
Subramanian Venkatesan, Mihaela Angelova, Clare Puttick, Haoran Zhai, Deborah R Caswell, Sebastijan Hobor

Cancer Discov· October 2021

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Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis.
Cristina Morales Torres, Mary Y Wu, Sebastijan Hobor, Elanor N Wainwright, Matthew J Martin

Nat Commun· April 2020

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Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses.
Julianna Blagih, Fabio Zani, Probir Chakravarty, Marc Hennequart, Steven Pilley, Sebastijan Hobor

Cell Rep· January 2020

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Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.
Samra Turajlic, Hang Xu, Kevin Litchfield, Andrew Rowan, Stuart Horswell, Sebastijan Hobor

Cell· April 2018

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BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer.
Carlos López-García, Laurent Sansregret, Enric Domingo, Nicholas McGranahan, Sebastijan Hobor

Cancer Cell· January 2017

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Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
Giulia Siravegna, Benedetta Mussolin, Michela Buscarino, Giorgio Corti, Andrea Cassingena, Sebastijan Hobor

Nat Med· July 2015

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Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
Giulia Siravegna, Benedetta Mussolin, Michela Buscarino, Giorgio Corti, Andrea Cassingena, Sebastijan Hobor

Nat Med· July 2015

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Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer.
Sabrina Arena, Beatriz Bellosillo, Giulia Siravegna, Alejandro Martínez, Israel Cañadas, Sebastijan Hobor

Clin Cancer Res· May 2015

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TGFα and amphiregulin paracrine network promotes resistance to EGFR blockade in colorectal cancer cells.
Sebastijan Hobor, Beth O Van Emburgh, Emily Crowley, Sandra Misale, Federica Di Nicolantonio

Clin Cancer Res· December 2014

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Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma.
Chong Sun, Liqin Wang, Sidong Huang, Guus J J E Heynen, Anirudh Prahallad, Sebastijan Hobor

Nature· April 2014

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Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.
Chong Sun, Sebastijan Hobor, Andrea Bertotti, Davide Zecchin, Sidong Huang

Cell Rep· April 2014

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Blockade of EGFR and MEK intercepts heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer.
Sandra Misale, Sabrina Arena, Simona Lamba, Giulia Siravegna, Alice Lallo, Sebastijan Hobor

Sci Transl Med· February 2014

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KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy.
Emanuele Valtorta, Sandra Misale, Andrea Sartore-Bianchi, Iris D Nagtegaal, François Paraf, Sebastijan Hobor

Int J Cancer· September 2013

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Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer.
Alberto Bardelli, Simona Corso, Andrea Bertotti, Sebastijan Hobor, Emanuele Valtorta

Cancer Discov· June 2013

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Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.
Sandra Misale, Rona Yaeger, Sebastijan Hobor, Elisa Scala, Manickam Janakiraman

Nature· June 2012

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