Publications by authors named "Ken Kron"

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Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer.
Giacomo Grillo, Tina Keshavarzian, Simon Linder, Christopher Arlidge, Lisanne Mout, Ken J Kron

Cancer Discov· November 2023

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Transcriptome-Wide Off-Target Effects of Steric-Blocking Oligonucleotides.
Erle M Holgersen, Shreshth Gandhi, Yongchao Zhou, Jinkuk Kim, Brandon Vaz, Ken Kron

Nucleic Acid Ther· December 2021

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Reorganization of the 3D Genome Pinpoints Noncoding Drivers of Primary Prostate Tumors.
James R Hawley, Stanley Zhou, Christopher Arlidge, Giacomo Grillo, Ken J Kron

Cancer Res· December 2021

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The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization.
Naoya Takayama, Alex Murison, Shin-Ichiro Takayanagi, Christopher Arlidge, Stanley Zhou, Ken Kron

Cell Stem Cell· March 2021

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variant c.1934T > G p.Met645Arg causes Wilson disease by promoting exon 6 skipping.
Daniele Merico, Carl Spickett, Matthew O'Hara, Boyko Kakaradov, Amit G Deshwar, Ken Kron

NPJ Genom Med· April 2020

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Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer.
Stanley Zhou, James R Hawley, Fraser Soares, Giacomo Grillo, Mona Teng, Ken J Kron

Nat Commun· January 2020

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Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors.
Parisa Mazrooei, Ken J Kron, Yanyun Zhu, Stanley Zhou, Giacomo Grillo

Cancer Cell· December 2019

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The Proteogenomic Landscape of Curable Prostate Cancer.
Ankit Sinha, Vincent Huang, Julie Livingstone, Jenny Wang, Natalie S Fox, Ken Kron

Cancer Cell· March 2019

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TMPRSS2-ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer.
Ken J Kron, Alexander Murison, Stanley Zhou, Vincent Huang, Takafumi N Yamaguchi

Nat Genet· September 2017

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Distinct DNA methylation alterations are associated with cribriform architecture and intraductal carcinoma in Gleason pattern 4 prostate tumors.
Ekaterina Olkhov-Mitsel, Farshid Siadat, Ken Kron, Liyang Liu, Andrea J Savio

Oncol Lett· July 2017

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Epigenome-Wide DNA Methylation Profiling Identifies Differential Methylation Biomarkers in High-Grade Bladder Cancer.
Ekaterina Olkhov-Mitsel, Andrea J Savio, Ken J Kron, Vaijayanti V Pethe, Thomas Hermanns

Transl Oncol· April 2017

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Genomic hallmarks of localized, non-indolent prostate cancer.
Michael Fraser, Veronica Y Sabelnykova, Takafumi N Yamaguchi, Lawrence E Heisler, Julie Livingstone, Ken Kron

Nature· January 2017

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Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer.
Swneke D Bailey, Kinjal Desai, Ken J Kron, Parisa Mazrooei, Nicholas A Sinnott-Armstrong

Nat Genet· October 2016

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Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.
Satoshi Inoue, Wanda Y Li, Alan Tseng, Isabel Beerman, Andrew J Elia, Ken J Kron

Cancer Cell· August 2016

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Dynamic interplay between locus-specific DNA methylation and hydroxymethylation regulates distinct biological pathways in prostate carcinogenesis.
Shivani N Kamdar, Linh T Ho, Ken J Kron, Ruth Isserlin, Theodorus van der Kwast

Clin Epigenetics· April 2016

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Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation.
Aline C Planello, Rajat Singhania, Ken J Kron, Swneke D Bailey, David Roulois

Oncotarget· March 2016

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Enhancer alterations in cancer: a source for a cell identity crisis.
Ken J Kron, Swneke D Bailey, Mathieu Lupien

Genome Med· December 2014

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Integrated analysis of epigenomic and genomic changes by DNA methylation dependent mechanisms provides potential novel biomarkers for prostate cancer.
Nicole M A White-Al Habeeb, Linh T Ho, Ekaterina Olkhov-Mitsel, Ken Kron, Vaijayanti Pethe

Oncotarget· September 2014

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Prognostic impact of intraductal carcinoma and large cribriform carcinoma architecture after prostatectomy in a contemporary cohort.
Dominique Trudel, Michelle R Downes, Jenna Sykes, Ken J Kron, John Trachtenberg

Eur J Cancer· June 2014

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Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation.
Frann Antignano, Kyle Burrows, Michael R Hughes, Jonathan M Han, Ken J Kron

J Clin Invest· May 2014

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Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression.
Punit Saraon, Dominique Trudel, Ken Kron, Apostolos Dmitromanolakis, John Trachtenberg

Prostate· April 2014

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Novel multiplex MethyLight protocol for detection of DNA methylation in patient tissues and bodily fluids.
Ekaterina Olkhov-Mitsel, Darko Zdravic, Ken Kron, Theodorus van der Kwast, Neil Fleshner

Sci Rep· March 2014

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Altered DNA methylation landscapes of polycomb-repressed loci are associated with prostate cancer progression and ERG oncogene expression in prostate cancer.
Ken Kron, Dominique Trudel, Vaijayanti Pethe, Laurent Briollais, Neil Fleshner

Clin Cancer Res· July 2013

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Quantitative DNA methylation analysis of genes coding for kallikrein-related peptidases 6 and 10 as biomarkers for prostate cancer.
Ekaterina Olkhov-Mitsel, Theodorus Van der Kwast, Ken J Kron, Hilmi Ozcelik, Laurent Briollais

Epigenetics· September 2012

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