Publications by authors named "Ken Newlander"

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Asymmetric synthesis of potent and orally bioavailable thiophene-based EZH2 inhibitors.
Xinrong Tian, Ken Newlander, Louis LaFrance, James Mack, James Brackley

Bioorg Med Chem Lett· November 2025

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Discovery of GSK1070916, a potent and selective inhibitor of Aurora B/C kinase.
Nicholas D Adams, Jerry L Adams, Joelle L Burgess, Amita M Chaudhari, Robert A Copeland, Ken A Newlander

J Med Chem· May 2010

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Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295.
Xiangping Qian, Andrew McDonald, Han-Jie Zhou, Nicholas D Adams, Cynthia A Parrish, Ken A Newlander

ACS Med Chem Lett· April 2010

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Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin.
Steven D Knight, Nicholas D Adams, Joelle L Burgess, Amita M Chaudhari, Michael G Darcy, Ken A Newlander

ACS Med Chem Lett· April 2010

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GSK1070916, a potent Aurora B/C kinase inhibitor with broad antitumor activity in tissue culture cells and human tumor xenograft models.
Mary Ann Hardwicke, Catherine A Oleykowski, Ramona Plant, Jamin Wang, Qiaoyin Liao, Ken Newlander

Mol Cancer Ther· July 2009

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Biochemical characterization of GSK1070916, a potent and selective inhibitor of Aurora B and Aurora C kinases with an extremely long residence time1.
Kelly Anderson, Zhihong Lai, Octerloney B McDonald, J Darren Stuart, Eldridge N Nartey, Ken Newlander

Biochem J· May 2009

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Novel ATP-competitive kinesin spindle protein inhibitors.
Cynthia A Parrish, Nicholas D Adams, Kurt R Auger, Joelle L Burgess, Jeffrey D Carson, Ken A Newlander

J Med Chem· October 2007

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