Publications by authors named "Ken Ong"

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Rare Variants in HTRA1, SGTB, and RBM12 Confer Risk of Atherosclerotic Cardiovascular Disease Independent of Traditional Cardiovascular Risk Factors.
Sam M Lockhart, Anuradhika Puri, Yajie Zhao, Vladimir Saudek, Eugene J Gardner, Ken K Ong

Circ Genom Precis Med· December 2025

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EndoCompass Project: Research Roadmap for Reproductive and Developmental Endocrinology.
Martine Cools, Csilla Krausz, Anders Juul, Djuro Macut, Marianne Skovsager Andersen, Ken Ong

Horm Res Paediatr· December 2025

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The LIFE-MET trial: effect of insulin sensitization on pubertal progression following lifestyle intervention and/or treatment with metformin in girls with early puberty and overweight: study protocol for a randomized, placebo-controlled trial.
Grith Laerkholm, Line Anker Bang Thybo, Astrid Bruun Rasmussen, Ann-Margrethe Rønholt Christensen, Annette Korsholm Mouritsen, Ken K Ong

Trials· November 2025

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Effects of Rare Coding Variants in Severe Early-Onset Obesity Genes in the Population-Based UK Biobank Study.
Raina Y Jia, Sam Lockhart, Brian Y H Lam, Yajie Zhao, Katherine A Kentistou, Ken K Ong

J Clin Endocrinol Metab· October 2025

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Bidirectional Mendelian Randomization Indicates Causal Relationships Between Circulating Branched-Chain Amino Acids and Metabolic Health.
Raina Y Jia, Jian-Hua Chen, Sam Lockhart, Brian Y H Lam, Katherine A Kentistou, Ken K Ong

Diabetes· October 2025

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Different Intensities of Physical Activity Substituted for Sedentary Time and Risk of Type 2 Diabetes: Integration of Genetics and Wearable Data.
Qiaoxin Shi, Haeyoon Jang, Paul James Collings, Mengyao Wang, Ziyuan Chen, Ken K Ong

Mayo Clin Proc· October 2025

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Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health.
Yajie Zhao, Sam Lockhart, Jimmy Liu, Xihao Li, Adrian Cortes, Ken K Ong

Nat Genet· October 2025

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Exploring the Use of Digital Technology to Support Health Behavior Change in Young People Under the Care of Complications of Excess Weight (CCEW) Clinics: Qualitative Patient-Centered Design Study.
Brioney Gee, Bonnie Teague, Matt Farrar, Victoria Farrar, Dorothy Szinay, Ken K Ong

JMIR Form Res· October 2025

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EndoCompass project: research roadmap for reproductive and developmental endocrinology.
Martine Cools, Csilla Krausz, Anders Juul, Djuro Macut, Marianne Skovsager Andersen, Ken Ong

Eur J Endocrinol· October 2025

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Higher circulating testosterone linked to higher CAD risk in men: Mendelian randomisation and survival analyses.
Emily J Morbey, Felix R Day, Adam S Butterworth, Nicholas J Wareham, John R B Perry, Ken K Ong

J Clin Endocrinol Metab· October 2025

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Parent-focused behavioural interventions for the prevention of early childhood obesity (TOPCHILD): a systematic review and individual participant data meta-analysis.
Kylie E Hunter, David Nguyen, Sol Libesman, Jonathan G Williams, Mason Aberoumand, Ken K Ong

Lancet· September 2025

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Association of IGF-1 levels with height from childhood to adulthood: An observational and Mendelian randomization study.
Benjamin De La Barrera, Samuel De La Barrera, Isabel Gamache, Soren Harnois-Leblanc, Kaossarath Fagbemi, Ken K Ong

J Clin Endocrinol Metab· September 2025

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Updating the Scientific Advisory Committee on Nutrition's Framework for the evaluation of evidence.
Mamta Singh, Rachel Elsom, Adrienne Cullum, Russell J de Souza, Darren C Greenwood, Ken K Ong

Br J Nutr· August 2025

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Updating the Scientific Advisory Committee on Nutrition's Framework for the evaluation of evidence - CORRIGENDUM.
Mamta Singh, Rachel Elsom, Adrienne Cullum, Russell J de Souza, Darren C Greenwood, Ken K Ong

Br J Nutr· August 2025

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The causal role of endocrine disrupting chemicals in pubertal timing: a Mendelian randomization study.
Melody Zuo, Isabel Gamache, Kaossarath Fagbemi, Felix R Day, Ken K Ong

J Pediatr Endocrinol Metab· July 2025

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Protein-truncating variants in UQCRC1 are associated with Parkinson's disease: evidence from half-million people.
Xiaoxi Jing, Zongzhi Liu, Wenwen Li, Kaiyan Ma, Jiaxiang Zhang, Jiecong Lin, Ken K Ong

NPJ Parkinsons Dis· May 2025

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Physical Activity by Accelerometry is Prospectively Associated With Lower Testosterone and Hirsutism Score Among Adolescent Girls.
Tricia M Peters, Tuck Seng Cheng, Soren Brage, Ken K Ong

J Adolesc Health· April 2025

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Genetic determinants of proteomic aging.
Alexander Mörseburg, Yajie Zhao, Katherine A Kentistou, John R B Perry, Ken K Ong

NPJ Aging· April 2025

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Lifecourse research in cancer: context, challenges, and opportunities when exploring exposures in early life and cancer risk in adulthood.
Jennifer L Baker, Vanessa L Z Gordon-Dseagu, Trudy Voortman, Doris Chan, Zdenko Herceg, Ken Ong

Health Open Res· March 2025

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Canine genome-wide association study identifies as an obesity gene in dogs and humans.
Natalie J Wallis, Alyce McClellan, Alexander Mörseburg, Katherine A Kentistou, Aqfan Jamaluddin, Ken K Ong

Science· March 2025

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Genetic Susceptibility to Type 2 Diabetes, Television Viewing, and Atherosclerotic Cardiovascular Disease Risk.
Mengyao Wang, Paul James Collings, Felix R Day, Ken K Ong, Soren Brage

J Am Heart Assoc· March 2025

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Deleterious variants in intolerant genes reveal new candidates for self-limited delayed puberty.
Raíssa C Rezende, Wen He, Lena R Kaisinger, Antonio M Lerario, Evan C Schafer, Ken K Ong

Eur J Endocrinol· March 2025

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Behavioural components and delivery features of early childhood obesity prevention interventions: intervention coding of studies in the TOPCHILD Collaboration systematic review.
Brittany J Johnson, Paul M Chadwick, Samantha Pryde, Anna Lene Seidler, Kylie E Hunter, Ken K Ong

Int J Behav Nutr Phys Act· February 2025

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A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein synthesis regulation.
Sophia Y Breusegem, Jack Houghton, Raquel Romero-Bueno, Adrián Fragoso-Luna, Katherine A Kentistou, Ken K Ong

Nat Commun· February 2025

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Rare variant associations with birth weight identify genes involved in adipose tissue regulation, placental function and insulin-like growth factor signalling.
Katherine A Kentistou, Brandon E M Lim, Lena R Kaisinger, Valgerdur Steinthorsdottir, Luke N Sharp, Ken K Ong

Nat Commun· January 2025

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