Publications by authors named "Kenichi Hanada"

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Identification and structural characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3.
Malcolm J W Sim, Ken-Ichi Hanada, Zachary Stotz, Zhiya Yu, Jinghua Lu

Eur J Immunol· September 2024

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Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens.
Anup Y Parikh, Robert Masi, Billel Gasmi, Ken-Ichi Hanada, Maria Parkhurst

Cancer Immunol Immunother· October 2023

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Identification of neoepitope reactive T-cell receptors guided by HLA-A*03:01 and HLA-A*11:01 immunopeptidomics.
Catherine M Ade, Matthew J Sporn, Sudipto Das, Zhiya Yu, Ken-Ichi Hanada

J Immunother Cancer· September 2023

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A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers.
Ken-Ichi Hanada, Chihao Zhao, Raul Gil-Hoyos, Jared J Gartner, Christopher Chow-Parmer

Cancer Cell· May 2022

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Proteogenomic Analysis Unveils the HLA Class I-Presented Immunopeptidome in Melanoma and EGFR-Mutant Lung Adenocarcinoma.
Yue A Qi, Tapan K Maity, Constance M Cultraro, Vikram Misra, Xu Zhang, Ken-Ichi Hanada

Mol Cell Proteomics· March 2022

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Cancer immunotherapy using artificial adjuvant vector cells to deliver NY-ESO-1 antigen to dendritic cells in situ.
Shin-Ichiro Fujii, Satoru Yamasaki, Kenichi Hanada, Shogo Ueda, Masami Kawamura

Cancer Sci· March 2022

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Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers.
Frank J Lowery, Sri Krishna, Rami Yossef, Neilesh B Parikh, Praveen D Chatani, Ken-Ichi Hanada

Science· February 2022

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A machine learning model for ranking candidate HLA class I neoantigens based on known neoepitopes from multiple human tumor types.
Jared J Gartner, Maria R Parkhurst, Alena Gros, Eric Tran, Mohammad S Jafferji, Ken-Ichi Hanada

Nat Cancer· May 2021

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Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus.
François Van Laethem, Ingrid Saba, Jinghua Lu, Abhisek Bhattacharya, Xuguang Tai, Ken-Ichi Hanada

Front Immunol· April 2021

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An effective mouse model for adoptive cancer immunotherapy targeting neoantigens.
Ken-Ichi Hanada, Zhiya Yu, Gabrielle R Chappell, Adam S Park, Nicholas P Restifo

JCI Insight· May 2019

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Cytotoxic T-lymphocyte-associated protein 4 expressed by melanoma cells does not affect melanoma-specific cytotoxic T lymphocytes in the effector phase.
Takashi Inozume, Ken-Ichi Hanada, Kazuyo Takeda, Tatsuo Maeda, Kazutoshi Harada

J Dermatol· January 2019

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Preclinical Evaluation of Chimeric Antigen Receptors Targeting CD70-Expressing Cancers.
Qiong J Wang, Zhiya Yu, Ken-Ichi Hanada, Krishna Patel, David Kleiner

Clin Cancer Res· May 2017

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Genomic profiling of multiple sequentially acquired tumor metastatic sites from an "exceptional responder" lung adenocarcinoma patient reveals extensive genomic heterogeneity and novel somatic variants driving treatment response.
Romi Biswas, Shaojian Gao, Constance M Cultraro, Tapan K Maity, Abhilash Venugopalan, Ken-Ichi Hanada

Cold Spring Harb Mol Case Stud· November 2016

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Identification of T-cell Receptors Targeting KRAS-Mutated Human Tumors.
Qiong J Wang, Zhiya Yu, Kayla Griffith, Ken-ichi Hanada, Nicholas P Restifo

Cancer Immunol Res· March 2016

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Type I cytokines synergize with oncogene inhibition to induce tumor growth arrest.
Nicolas Acquavella, David Clever, Zhiya Yu, Melody Roelke-Parker, Douglas C Palmer, Ken-Ichi Hanada

Cancer Immunol Res· January 2015

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Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics.
Joseph G Crompton, Madhusudhanan Sukumar, Rahul Roychoudhuri, David Clever, Alena Gros, Ken-Ichi Hanada

Cancer Res· January 2015

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PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors.
Alena Gros, Paul F Robbins, Xin Yao, Yong F Li, Simon Turcotte, Ken-Ichi Hanada

J Clin Invest· May 2014

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Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytes.
Daniel Abate-Daga, Ken-ichi Hanada, Jeremy L Davis, James C Yang, Steven A Rosenberg

Blood· August 2013

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Vaccination with antigen-transfected, NKT cell ligand-loaded, human cells elicits robust in situ immune responses by dendritic cells.
Kanako Shimizu, Takuya Mizuno, Jun Shinga, Miki Asakura, Kazuhiro Kakimi, Kenichi Hanada

Cancer Res· January 2013

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Double or nothing on cancer immunotherapy.
Ken-ichi Hanada, Nicholas P Restifo

Nat Biotechnol· January 2013

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Distinctive features of the differentiated phenotype and infiltration of tumor-reactive lymphocytes in clear cell renal cell carcinoma.
Qiong J Wang, Ken-Ichi Hanada, Paul F Robbins, Yong F Li, James C Yang

Cancer Res· December 2012

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αβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificities.
Anastasia N Tikhonova, François Van Laethem, Ken-ichi Hanada, Jinghua Lu, Leonid A Pobezinsky

Immunity· January 2012

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An antigenic peptide produced by reverse splicing and double asparagine deamidation.
Alexandre Dalet, Paul F Robbins, Vincent Stroobant, Nathalie Vigneron, Yong F Li, Ken-ichi Hanada

Proc Natl Acad Sci U S A· July 2011

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Molecular identification of an MHC-independent ligand recognized by a human {alpha}/{beta} T-cell receptor.
Ken-ichi Hanada, Qiong J Wang, Takashi Inozume, James C Yang

Blood· May 2011

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Development of a genetically-modified novel T-cell receptor for adoptive cell transfer against renal cell carcinoma.
Qiong J Wang, Ken-ichi Hanada, Steven A Feldman, Yangbing Zhao, Takashi Inozume

J Immunol Methods· March 2011

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