Publications by authors named "Kenneth B Marcu"

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IKKα-Mediated Noncanonical NF-κB Signaling Is Required To Support Murine Gammaherpesvirus 68 Latency .
Brandon Cieniewicz, Varvara Kirillov, Isabel Daher, Xiaofan Li, Darby G Oldenburg, Kenneth B Marcu

J Virol· May 2022

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Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases.
Eleonora Olivotto, Manuela Minguzzi, Stefania D'Adamo, Annalisa Astolfi, Spartaco Santi, Kenneth B Marcu

Sci Rep· November 2021

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Canonical NF-κB Promotes Lung Epithelial Cell Tumour Growth by Downregulating the Metastasis Suppressor CD82 and Enhancing Epithelial-to-Mesenchymal Cell Transition.
Eugenia Roupakia, Evangelia Chavdoula, Georgia Karpathiou, Giannis Vatsellas, Dimitrios Chatzopoulos, Kenneth B Marcu

Cancers (Basel)· August 2021

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CHUK/IKK-α loss in lung epithelial cells enhances NSCLC growth associated with HIF up-regulation.
Evangelia Chavdoula, David M Habiel, Eugenia Roupakia, Georgios S Markopoulos, Eleni Vasilaki, Kenneth B Marcu

Life Sci Alliance· December 2019

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Epigenetic Regulation of Inflammatory Cytokine-Induced Epithelial-To-Mesenchymal Cell Transition and Cancer Stem Cell Generation.
Georgios S Markopoulos, Eugenia Roupakia, Kenneth B Marcu, Evangelos Kolettas

Cells· September 2019

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Inducible knockout of CHUK/IKKα in adult chondrocytes reduces progression of cartilage degradation in a surgical model of osteoarthritis.
Kirsty L Culley, Samantha G Lessard, Jordan D Green, Justin Quinn, Jun Chang, Kenneth B Marcu

Sci Rep· June 2019

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Phenotypic instability of chondrocytes in osteoarthritis: on a path to hypertrophy.
Purva Singh, Kenneth B Marcu, Mary B Goldring, Miguel Otero

Ann N Y Acad Sci· April 2019

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Roles of NF-κB Signaling in the Regulation of miRNAs Impacting on Inflammation in Cancer.
Georgios S Markopoulos, Eugenia Roupakia, Maria Tokamani, Georgia Alabasi, Raphael Sandaltzopoulos, Kenneth B Marcu

Biomedicines· March 2018

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A step-by-step microRNA guide to cancer development and metastasis.
Georgios S Markopoulos, Eugenia Roupakia, Maria Tokamani, Evangelia Chavdoula, Maria Hatziapostolou, Kenneth B Marcu

Cell Oncol (Dordr)· August 2017

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RTA Occupancy of the Origin of Lytic Replication during Murine Gammaherpesvirus 68 Reactivation from B Cell Latency.
Alexis L Santana, Darby G Oldenburg, Varvara Kirillov, Laraib Malik, Qiwen Dong, Kenneth B Marcu

Pathogens· February 2017

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Pathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiation.
Eleonora Olivotto, Miguel Otero, Kenneth B Marcu, Mary B Goldring

RMD Open· November 2015

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Cell migration to CXCL12 requires simultaneous IKKα and IKKβ-dependent NF-κB signaling.
Marianna Penzo, David M Habiel, Mahalakshmi Ramadass, Richard R Kew, Kenneth B Marcu

Biochim Biophys Acta· September 2014

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IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation.
Eleonora Olivotto, Miguel Otero, Annalisa Astolfi, Daniela Platano, Annalisa Facchini, Kenneth B Marcu

PLoS One· April 2014

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IKKβ in myeloid cells controls the host response to lethal and sublethal Francisella tularensis LVS infection.
Sylvia Samaniego, Kenneth B Marcu

PLoS One· July 2013

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Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.
Ko Hashimoto, Miguel Otero, Kei Imagawa, María C de Andrés, Jonathan M Coico, Kenneth B Marcu

J Biol Chem· April 2013

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The canonical NF-κB pathway differentially protects normal and human tumor cells from ROS-induced DNA damage.
Alexandros Sfikas, Christina Batsi, Evangelia Tselikou, George Vartholomatos, Nikolaos Monokrousos, Kenneth B Marcu

Cell Signal· November 2012

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The IKKα-dependent NF-κB p52/RelB noncanonical pathway is essential to sustain a CXCL12 autocrine loop in cells migrating in response to HMGB1.
Richard R Kew, Marianna Penzo, David M Habiel, Kenneth B Marcu

J Immunol· March 2012

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Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis.
Mary B Goldring, Kenneth B Marcu

Trends Mol Med· February 2012

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E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress.
Miguel Otero, Darren A Plumb, Kaneyuki Tsuchimochi, Cecilia L Dragomir, Ko Hashimoto, Kenneth B Marcu

J Biol Chem· January 2012

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A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.
Ying Zheng, Sarit Lilo, Igor E Brodsky, Yue Zhang, Ruslan Medzhitov, Kenneth B Marcu

PLoS Pathog· April 2011

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Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis.
Mary B Goldring, Miguel Otero, Darren A Plumb, Cecilia Dragomir, Marta Favero, Kenneth B Marcu

Eur Cell Mater· February 2011

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TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype.
Gianluca Storci, Pasquale Sansone, Sara Mari, Gabriele D'Uva, Simona Tavolari, Kenneth B Marcu

J Cell Physiol· November 2010

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Matrix metalloproteinase 13 loss associated with impaired extracellular matrix remodeling disrupts chondrocyte differentiation by concerted effects on multiple regulatory factors.
Rosa Maria Borzí, Eleonora Olivotto, Stefania Pagani, Roberta Vitellozzi, Simona Neri, Kenneth B Marcu

Arthritis Rheum· August 2010

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NF-kappaB signaling: multiple angles to target OA.
Kenneth B Marcu, Miguel Otero, Eleonora Olivotto, Rosa Maria Borzi, Mary B Goldring

Curr Drug Targets· May 2010

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Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected].
Marianna Penzo, Raffaella Molteni, Tomomi Suda, Sylvia Samaniego, Angela Raucci, Kenneth B Marcu

J Immunol· April 2010

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