Publications by authors named "Kenneth Durbin"

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Automated Enzymatic Deglycosylation of Monoclonal Antibody with the SampleStream Platform.
Troy D Fisher, Philip D Compton, Matthew T Robey, Ryan T Fellers, Kenneth R Durbin

J Am Soc Mass Spectrom· December 2025

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Native top-down proteomics enables discovery in endocrine-resistant breast cancer.
Fabio P Gomes, Kenneth R Durbin, Kevin Schauer, Jerome C Nwachukwu, Robin R Kobylski

Nat Chem Biol· August 2025

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Fast and Accurate Charge State Deconvolution of Protein Mass Spectra.
Kenneth R Durbin, Matthew T Robey, Joseph B Greer, Ryan T Fellers, Aaron O Bailey

Anal Chem· July 2025

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Standardized workflow for multiplexed charge detection mass spectrometry on orbitrap analyzers.
Pei Su, John P McGee, Michael A R Hollas, Ryan T Fellers, Kenneth R Durbin

Nat Protoc· June 2025

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Top-down mass spectrometry analysis of capsid proteins of recombinant adeno-associated virus using multiple ion activations and proton transfer charge reduction.
Jake T Kline, Jingjing Huang, Linda B Lieu, Kristina Srzentić, David Bergen, Kenneth R Durbin

Proteomics· March 2025

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Improving Top-Down Sequence Coverage with Targeted Fragment Matching.
Matthew T Robey, Kenneth R Durbin

J Am Soc Mass Spectrom· December 2024

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Filling the gaps in peptide maps with a platform assay for top-down characterization of purified protein samples.
Aaron O Bailey, Kenneth R Durbin, Matthew T Robey, Lee K Palmer, William K Russell

Proteomics· November 2024

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Towards a universal method for middle-down analysis of antibodies via proton transfer charge reduction-Orbitrap mass spectrometry.
Ryan N Oates, Linda B Lieu, Jake T Kline, Christopher Mullen, Kristina Srzentić, Kenneth R Durbin

Anal Bioanal Chem· November 2024

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Enhanced Payload Localization in Antibody-Drug Conjugates Using a Middle-Down Mass Spectrometry Approach with Proton Transfer Charge Reduction.
Linda B Lieu, Cynthia Nagy, Jingjing Huang, Christopher Mullen, Graeme C McAlister, Kenneth R Durbin

Anal Chem· November 2024

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BCL-X-targeting antibody-drug conjugates are active in preclinical models and mitigate on-mechanism toxicity of small-molecule inhibitors.
Andrew S Judd, Bhupinder Bawa, Wayne R Buck, Zhi-Fu Tao, Yingchun Li, Kenneth R Durbin

Sci Adv· October 2024

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Targeted Quantification of Proteoforms in Complex Samples by Proteoform Reaction Monitoring.
Che-Fan Huang, Jake T Kline, Fernanda Negrão, Matthew T Robey, Timothy K Toby, Kenneth R Durbin

Anal Chem· February 2024

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Author Correction: Automated imaging and identification of proteoforms directly from ovarian cancer tissue.
John P McGee, Pei Su, Kenneth R Durbin, Michael A R Hollas, Nicholas W Bateman

Nat Commun· December 2023

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Orbitrap Mass Spectrometry and High-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) Enable the in-Depth Analysis of Human Serum Proteoforms.
Jake T Kline, Michael W Belford, Cornelia L Boeser, Romain Huguet, Ryan T Fellers, Kenneth R Durbin

J Proteome Res· November 2023

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Advancing Intact Protein Quantitation with Updated Deconvolution Routines.
Matthew T Robey, Daisha Utley, Joseph B Greer, Ryan T Fellers, Neil L Kelleher, Kenneth R Durbin

Anal Chem· October 2023

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Automated imaging and identification of proteoforms directly from ovarian cancer tissue.
John P McGee, Pei Su, Kenneth R Durbin, Michael A R Hollas, Nicholas W Bateman

Nat Commun· October 2023

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ProSight Native: Defining Protein Complex Composition from Native Top-Down Mass Spectrometry Data.
Kenneth R Durbin, Matthew T Robey, Lilien N Voong, Ryan T Fellers, Corinne A Lutomski

J Proteome Res· August 2023

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Native top-down proteomics reveals EGFR-ERα signaling crosstalk in breast cancer cells dissociates NUTF2 dimers to modulate ERα signaling and cell growth.
John Yates, Fabio Gomes, Kenneth Durbin, Kevin Schauer, Jerome Nwachukwu

Res Sq· July 2023

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Improved Label-Free Quantification of Intact Proteoforms Using Field Asymmetric Ion Mobility Spectrometry.
Jake T Kline, Michael W Belford, Jingjing Huang, Joseph B Greer, David Bergen, Kenneth R Durbin

Anal Chem· June 2023

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High-Throughput Deconvolution of Intact Protein Mass Spectra for the Screening of Covalent Inhibitors.
Fan Pu, Kevan T Knizner, Matthew T Robey, Andrew J Radosevich, Scott A Ugrin, Kenneth R Durbin

J Am Soc Mass Spectrom· December 2022

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Highly multiplexed, label-free proteoform imaging of tissues by individual ion mass spectrometry.
Pei Su, John P McGee, Kenneth R Durbin, Michael A R Hollas, Manxi Yang

Sci Adv· August 2022

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ProSight Annotator: Complete control and customization of protein entries in UniProt XML files.
Joseph B Greer, Bryan P Early, Kenneth R Durbin, Steven M Patrie, Paul M Thomas

Proteomics· June 2022

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Quantitation of Plasma Membrane Drug Transporters in Kidney Tissue and Cell Lines Using a Novel Proteomic Approach Enabled a Prospective Prediction of Metformin Disposition.
Ryota Kikuchi, William J Chiou, Kenneth R Durbin, John P Savaryn, Junli Ma

Drug Metab Dispos· October 2021

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Sequential Ion-Ion Reactions for Enhanced Gas-Phase Sequencing of Large Intact Proteins in a Tribrid Orbitrap Mass Spectrometer.
Jake T Kline, Christopher Mullen, Kenneth R Durbin, Ryan N Oates, Romain Huguet

J Am Soc Mass Spectrom· September 2021

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Reassembling protein complexes after controlled disassembly by top-down mass spectrometry in native mode.
Luis F Schachner, Denise P Tran, Alexander Lee, John P McGee, Kevin Jooss, Kenneth Durbin

Int J Mass Spectrom· July 2021

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