Publications by authors named "Kenneth G Carson"

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Discovery of PqsE Thioesterase Inhibitors for Using DNA-Encoded Small Molecule Library Screening.
Julie S Valastyan, Michael R Tota, Isabelle R Taylor, Vasiliki Stergioula, Graham A B Hone, Kenneth G Carson

ACS Chem Biol· February 2020

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LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice.
David R Powell, Melinda G Smith, Deon D Doree, Angela L Harris, Jennifer Greer, Kenneth G Carson

J Pharmacol Exp Ther· July 2017

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Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes.
Nicole C Goodwin, Zhi-Ming Ding, Bryce A Harrison, Eric D Strobel, Angela L Harris, Kenneth G Carson

J Med Chem· January 2017

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Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase.
James E Tarver, Praveen K Pabba, Joseph Barbosa, Qiang Han, Michael W Gardyan, Kenneth G Carson

Bioorg Med Chem Lett· March 2016

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4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase.
Qiang Han, Praveen K Pabba, Joseph Barbosa, Ross Mabon, Jason P Healy, Kenneth G Carson

Bioorg Med Chem Lett· February 2016

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Genetic deletion of Mst1 alters T cell function and protects against autoimmunity.
Konstantin V Salojin, Brian D Hamman, Wei Chun Chang, Kanchan G Jhaver, Amin Al-Shami, Kenneth G Carson

PLoS One· January 2015

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Inhibition of sphingosine 1-phosphate lyase for the treatment of rheumatoid arthritis: discovery of (E)-1-(4-((1R,2S,3R)-1,2,3,4-tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone oxime (LX2931) and (1R,2S,3R)-1-(2-(isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932).
Jeffrey T Bagdanoff, Michael S Donoviel, Amr Nouraldeen, Marianne Carlsen, Theodore C Jessop, Kenneth G Carson

J Med Chem· December 2010

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5-Fluorocytosine derivatives as inhibitors of deoxycytidine kinase.
James E Tarver, Theodore C Jessop, Marianne Carlsen, David J Augeri, Qinghong Fu, Kenneth G Carson

Bioorg Med Chem Lett· December 2009

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Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors.
Theodore C Jessop, James E Tarver, Marianne Carlsen, Amy Xu, Jason P Healy, Kenneth G Carson

Bioorg Med Chem Lett· December 2009

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Inhibition of sphingosine-1-phosphate lyase for the treatment of autoimmune disorders.
Jeffrey T Bagdanoff, Michael S Donoviel, Amr Nouraldeen, James Tarver, Qinghong Fu, Kenneth G Carson

J Med Chem· July 2009

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Synthesis and structure-activity relationship of 2-amino-3-heteroaryl-quinoxalines as non-peptide, small-molecule antagonists for interleukin-8 receptor.
Jie Jack Li, Kenneth G Carson, Bharat K Trivedi, Wen Song Yue, Qing Ye

Bioorg Med Chem· August 2003

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Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures(1).
Ahmed F. Abdel-Magid, Kenneth G. Carson, Bruce D. Harris, Cynthia A. Maryanoff, Rekha D. Shah

J Org Chem· May 1996

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