Publications by authors named "Kenneth L Rock"

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Alternate MHC I Antigen Presentation Pathways Allow CD8+ T-cell Recognition and Killing of Cancer Cells in the Absence of β2M or TAP.
Freidrich M Cruz, Laura A A Orellano, Amanda Chan, Kenneth L Rock

Cancer Immunol Res· January 2025

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GENETIC ABLATION OF THE C-TYPE LECTIN RECEPTOR CLEC2D INCREASES PERITONITIS MORTALITY, INFLAMMATION, AND PHYSIOLOGY WITHOUT DIMINISHING ORGAN INJURY.
Allan E Stolarski, Jiann-Jyh Lai, Jiyoun Kim, Kenneth L Rock, Daniel Remick

Shock· September 2024

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Tumor immune evasion through loss of MHC class-I antigen presentation.
Gulce Sari, Kenneth L Rock

Curr Opin Immunol· August 2023

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Pathways of MHC I cross-presentation of exogenous antigens.
Freidrich M Cruz, Amanda Chan, Kenneth L Rock

Semin Immunol· March 2023

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Tetraspanin-5-mediated MHC class I clustering is required for optimal CD8 T cell activation.
Jeff D Colbert, Freidrich M Cruz, Christina E Baer, Kenneth L Rock

Proc Natl Acad Sci U S A· October 2022

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Cancer Immune Evasion Through Loss of MHC Class I Antigen Presentation.
Karthik Dhatchinamoorthy, Jeff D Colbert, Kenneth L Rock

Front Immunol· September 2021

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Cross-presentation of exogenous antigens on MHC I molecules.
Jeff D Colbert, Freidrich M Cruz, Kenneth L Rock

Curr Opin Immunol· June 2020

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How a tailor achieves the perfect fit.
Jeff D Colbert, Kenneth L Rock

J Biol Chem· May 2020

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The GTPase Rab39a promotes phagosome maturation into MHC-I antigen-presenting compartments.
Freidrich M Cruz, Jeff D Colbert, Kenneth L Rock

EMBO J· January 2020

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Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury.
Jiann-Jyh Lai, Freidrich M Cruz, Kenneth L Rock

Immunity· January 2020

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Frequent Loss of IRF2 in Cancers Leads to Immune Evasion through Decreased MHC Class I Antigen Presentation and Increased PD-L1 Expression.
Barry A Kriegsman, Pranitha Vangala, Benjamin J Chen, Paul Meraner, Abraham L Brass, Kenneth L Rock

J Immunol· October 2019

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Frontline Science: Multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1β activation.
Gregory M Orlowski, Shruti Sharma, Jeff D Colbert, Matthew Bogyo, Stephanie A Robertson, Kenneth L Rock

J Leukoc Biol· July 2017

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The Biology and Underlying Mechanisms of Cross-Presentation of Exogenous Antigens on MHC-I Molecules.
Freidrich M Cruz, Jeff D Colbert, Elena Merino, Barry A Kriegsman, Kenneth L Rock

Annu Rev Immunol· April 2017

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Present Yourself! By MHC Class I and MHC Class II Molecules.
Kenneth L Rock, Eric Reits, Jacques Neefjes

Trends Immunol· November 2016

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Specialized proteasome subunits have an essential role in the thymic selection of CD8(+) T cells.
Eleanor Z Kincaid, Shigeo Murata, Keiji Tanaka, Kenneth L Rock

Nat Immunol· August 2016

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The Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoan Parasite Trypanosoma cruzi.
Jonatan Ersching, José R Vasconcelos, Camila P Ferreira, Braulia C Caetano, Alexandre V Machado, Kenneth L Rock

PLoS Pathog· April 2016

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Correction: Multiple Cathepsins Promote Pro-IL-1β Synthesis and NLRP3-Mediated IL-1β Activation.
Gregory M Orlowski, Jeff D Colbert, Shruti Sharma, Matthew Bogyo, Stephanie A Robertson, Kenneth L Rock

J Immunol· January 2016

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Evaluation of the contribution of multiple DAMPs and DAMP receptors in cell death-induced sterile inflammatory responses.
Hiroshi Kataoka, Hajime Kono, Zubin Patel, Yoshitaka Kimura, Kenneth L Rock

PLoS One· December 2015

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Multiple Cathepsins Promote Pro-IL-1β Synthesis and NLRP3-Mediated IL-1β Activation.
Gregory M Orlowski, Jeff D Colbert, Shruti Sharma, Matthew Bogyo, Stephanie A Robertson, Kenneth L Rock

J Immunol· August 2015

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The xanthine oxidase inhibitor Febuxostat reduces tissue uric acid content and inhibits injury-induced inflammation in the liver and lung.
Hiroshi Kataoka, Ke Yang, Kenneth L Rock

Eur J Pharmacol· January 2015

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Re-examining class-I presentation and the DRiP hypothesis.
Kenneth L Rock, Diego J Farfán-Arribas, Jeff D Colbert, Alfred L Goldberg

Trends Immunol· April 2014

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Microbiota signalling through MyD88 is necessary for a systemic neutrophilic inflammatory response.
Dipti Karmarkar, Kenneth L Rock

Immunology· December 2013

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Substrate-induced protein stabilization reveals a predominant contribution from mature proteins to peptides presented on MHC class I.
Jeff D Colbert, Diego J Farfán-Arribas, Kenneth L Rock

J Immunol· December 2013

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Uric acid as a danger signal in gout and its comorbidities.
Kenneth L Rock, Hiroshi Kataoka, Jiann-Jyh Lai

Nat Rev Rheumatol· January 2013

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Using intein catalysis to probe the origin of major histocompatibility complex class I-presented peptides.
Diego J Farfán-Arribas, Lawrence J Stern, Kenneth L Rock

Proc Natl Acad Sci U S A· October 2012

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