Publications by authors named "Kenneth Murphy"

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The Making of a cDC1: Precision Programming of Progenitor Potential.
Theresa L Murphy, Kenneth M Murphy

Immunol Rev· January 2026

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WDFY4-dependent cross-presentation proceeds via a vacuolar antigen-processing route.
J Luke Postoak, Alyssa Koch, Sicong Shan, Ray A Ohara, Suin Jo, Theresa L Murphy, Kenneth M Murphy

Proc Natl Acad Sci U S A· December 2025

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S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis.
Mrinmoy Das, Mohammed Alasharee, Brian Woods, Saikat Mukherjee, Shira Kim, Kenneth M Murphy, George F Murphy

Immunity· November 2025

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A Validated Regulatory Network for Th17 Cell Specification.
Maria Ciofani, Aviv Madar, Carolina Galan, MacLean Sellars, Kieran Mace, Kenneth M Murphy

Cell· October 2025

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Type 1 classical dendritic cells govern long-term cardiac allograft acceptance.
Macee C Owen, Vinay R Penna, Hao Dun, Wenjun Li, Benjamin J Kopecky, Kenneth M Murphy

J Clin Invest· September 2025

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ID2 secures cDC1 specification by antagonizing E proteins at a pleiotropic enhancer.
Feiya Ou, Tian-Tian Liu, Siling Du, Jing Chen, Alyssa R Koch, Theresa L Murphy, Kenneth M Murphy

Res Sq· September 2025

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"What's in a name?" Clarifying the identity of RORγt+ antigen-presenting cells.
Feiya Ou, Kenneth M Murphy

J Exp Med· August 2025

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Combined Flt3L and CD40 agonism restores dendritic cell-driven T cell immunity in pancreatic cancer.
Graham D Hogg, Alyssa G Weinstein, Natalie L Kingston, Xiuting Liu, Olivia M Dres, Kenneth M Murphy

Sci Immunol· August 2025

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cDC1s Promote Atherosclerosis via Local Immunity and Are Targetable for Therapy.
Miguel Galán, Laura Fernández-Méndez, Vanessa Núñez, Marcos Femenía-Muiña, Pau Figuera-Belmonte, Kenneth M Murphy

Circ Res· July 2025

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C/EBPα activates expression in myeloid progenitors at the +56-kb enhancer to initiate cDC1 development.
Jing Chen, Tian-Tian Liu, Feiya Ou, Ray A Ohara, Suin Jo, Theresa L Murphy, Kenneth M Murphy

Sci Immunol· May 2025

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Shared pathway of WDFY4-dependent cross-presentation of immune complexes by cDC1 and cDC2.
Suin Jo, Ray A Ohara, Derek J Theisen, Sunkyung Kim, Tiantian Liu, Theresa L Murphy, Kenneth M Murphy

J Exp Med· April 2025

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Identification of antigen-presenting cell-T cell interactions driving immune responses to food.
Maria Cecilia Campos Canesso, Tiago Bruno Rezende de Castro, Sandra Nakandakari-Higa, Ainsley Lockhart, Julia Luehr, Kenneth M Murphy

Science· March 2025

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Tracing LYVE1 peritoneal fluid macrophages unveils two paths to resident macrophage repopulation with differing reliance on monocytes.
Alexandre Gallerand, Jichang Han, Rachel L Mintz, Jing Chen, Daniel D Lee, Kenneth M Murphy

bioRxiv· March 2025

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Atopic skin inflammation promotes systemic anaphylactic responses via IL-13 signaling in conventional dendritic cells.
Yasuyo Harada, Takanori Sasaki, Kazushige Obata-Ninomiya, Takahiro Matsuyama, Satoshi Ueha, Kenneth Murphy

Res Sq· February 2025

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Type I interferon signaling in dendritic cells limits direct antigen presentation and CD8 T cell responses against an arthritogenic alphavirus.
Christopher B Bullock, Leran Wang, Brian C Ware, Ngan Wagoner, Ray A Ohara, Kenneth M Murphy

mBio· December 2024

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Optimization of the Irf8 +32-kb enhancer disrupts dendritic cell lineage segregation.
Feiya Ou, Tian-Tian Liu, Pritesh Desai, Stephen T Ferris, Sunkyung Kim, Theresa L Murphy, Kenneth M Murphy

Nat Immunol· November 2024

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Anatomy of a superenhancer.
Sunkyung Kim, Tian-Tian Liu, Feiya Ou, Theresa L Murphy, Kenneth M Murphy

Adv Immunol· September 2024

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Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy.
Hussein Sultan, Yoshiko Takeuchi, Jeffrey P Ward, Naveen Sharma, Tian-Tian Liu, Kenneth M Murphy

Nature· August 2024

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Transcription factor C/EBPα is required for the development of Ly6C monocytes but not Ly6C monocytes.
Sunkyung Kim, Jing Chen, Feiya Ou, Tian-Tian Liu, Suin Jo, Theresa L Murphy, Kenneth M Murphy

Proc Natl Acad Sci U S A· April 2024

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IL-6 selectively suppresses cDC1 specification via C/EBPβ.
Sunkyung Kim, Jing Chen, Suin Jo, Feiya Ou, Stephen T Ferris, Theresa L Murphy, Kenneth M Murphy

J Exp Med· October 2023

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Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand.
Feiya Ou, Stephen T Ferris, Sunkyung Kim, Renee Wu, David A Anderson, Theresa L Murphy, Kenneth M Murphy

Eur J Immunol· September 2023

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Use of CRISPR/CAS9 Technologies to Study the Role of TLR in Dendritic Cell Subsets.
Giulia Mencarelli, Benedetta Pieroni, Kenneth M Murphy, Marco Gargaro

Methods Mol Biol· September 2023

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Recent progress in type 1 classical dendritic cell cross-presentation - cytosolic, vacuolar, or both?
Ray A Ohara, Kenneth M Murphy

Curr Opin Immunol· August 2023

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, , and promote nonclassical monocyte development.
Kevin W O'Connor, Tiantian Liu, Sunkyung Kim, Carlos G Briseño, Katia Georgopoulos, Theresa L Murphy, Kenneth M Murphy

Proc Natl Acad Sci U S A· August 2023

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interactions in the locus regulate stage-dependent enhancer activation.
Tian-Tian Liu, Feiya Ou, Julia A Belk, Prachi Bagadia, David A Anderson, Theresa L Murphy, Kenneth M Murphy

Genes Dev· April 2023

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