Publications by authors named "Kenneth Pearce"

Claim this Profile

Mentions over time

Mentions by platform

Video Views

6,876

Total Likes

110

Extended Reach

8,763

Social Features

4
A
A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics.
Kuan-Yi Lu, Xiangbo Yang, Matthew J G Eldridge, Rongfeng Sun, Rachel T Giorgio, Kenneth H Pearce

Nat Microbiol· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Expansion of DNA-Encoded Library Hits Using Generative Chemistry and Ultra-Large Compound Catalogs.
Brandon Novy, Shu-Hang Lin, Devan J Shell, Travis Maxfield, Eric M Merten, Kenneth H Pearce

bioRxiv· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Open-Source DNA-Encoded Library informatics Package for Design, Decoding, and Analysis: DELi.
James Wellnitz, Brandon Novy, Travis Maxfield, Shu-Hang Lin, Ivanna Zhilinskaya, Kenneth H Pearce

bioRxiv· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development of Next Generation Cell-Permeable Peptide Inhibitors for the Oncological Target MAGE-A4.
Jiwoong Lim, Lilly F Chiou, Brandon Novy, Emma J Chow, Jacqueline L Norris-Drouin, Kenneth H Pearce

J Med Chem· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A high-throughput assay platform to discover small molecule activators of the phospholipase PLC-γ2 to treat Alzheimer's disease.
Adam J Carr, Nicole Hajicek, Andy P Tsai, Padam P Acharya, P Brian Hardy, Kenneth H Pearce

J Biol Chem· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A covalent chemical probe for Chikungunya nsP2 cysteine protease with antialphaviral activity and proteome-wide selectivity.
Anirban Ghoshal, Edwin G Tse, Mohammad Anwar Hossain, Kesatebrhan Haile Asressu, Eric M Merten, Kenneth H Pearce

Sci Rep· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A multi-kinase inhibitor screen identifies inhibitors preserving stem-cell-like chimeric antigen receptor T cells.
Feifei Song, Ourania Tsahouridis, Simone Stucchi, Tara Walhart, Sophie Mendell, Kenneth H Pearce

Nat Immunol· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells.
Mélanie Uguen, Devan J Shell, Madhushika Silva, Yu Deng, Fengling Li, Kenneth H Pearce

Nat Commun· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of Inhibitors of virus nsP2 ATPase.
Hernan Navarro, John E Scott, Ginger R Smith, Pegah Ghiabi, Elisa Gibson, Kenneth H Pearce

bioRxiv· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PCNA-binding activity separates RNF168 functions in DNA replication and DNA double-stranded break signaling.
Yang Yang, Deepika Jayaprakash, Satpal S Jhujh, John J Reynolds, Steve Chen, Kenneth H Pearce

Nucleic Acids Res· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel small molecule screening assay using normal human chondrocytes toward osteoarthritis drug discovery.
Philip R Coryell, Paul B Hardy, Susan Chubinskaya, Kenneth H Pearce, Richard F Loeser

PLoS One· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Author Correction: A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.
Yanzhe Gao, Elizabeth Mutter-Rottmayer, Alicia M Greenwalt, Dennis Goldfarb, Feng Yan, Kenneth H Pearce

Nat Commun· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Covalent Chemical Probe for nsP2 Cysteine Protease with Antialphaviral Activity and Proteome-wide Selectivity.
Anirban Ghoshal, Edwin G Tse, Mohammad Anwar Hossain, Kesatebrhan Haile Asressu, Eric M Merten, Kenneth H Pearce

Res Sq· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.
Eric M Merten, John D Sears, Tina M Leisner, P Brian Hardy, Anirban Ghoshal, Kenneth H Pearce

Proc Natl Acad Sci U S A· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A host-directed adjuvant resuscitates and sensitizes intracellular bacterial persisters to antibiotics.
Kuan-Yi Lu, Xiangbo Yang, Matthew J G Eldridge, Nikki J Wagner, Brian Hardy, Kenneth H Pearce

bioRxiv· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of nsP2 Cysteine Protease with Antialphavirus Activity.
Anirban Ghoshal, Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J Brown, Meganathan Nandakumar, Kenneth H Pearce

J Med Chem· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A First-in-Class High-Throughput Screen to Discover Modulators of the Alternative Lengthening of Telomeres (ALT) Pathway.
Merrill M Froney, Christian R Cook, Alyssa M Cadiz, Katherine A Flinter, Sara T Ledeboer, Kenneth H Pearce

ACS Pharmacol Transl Sci· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells.
Mélanie Uguen, Devan J Shell, Madhushika Silva, Yu Deng, Fengling Li, Kenneth H Pearce

bioRxiv· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In silico fragment-based discovery of CIB1-directed anti-tumor agents by FRASE-bot.
Yi An, Jiwoong Lim, Marta Glavatskikh, Xiaowen Wang, Jacqueline Norris-Drouin, Kenneth H Pearce

Nat Commun· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of nsP2 Cysteine Protease with Anti-alphavirus Activity.
Anirban Ghoshal, Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J Brown, Eric M Merten, Kenneth H Pearce

bioRxiv· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.
Eric M Merten, John D Sears, Tina M Leisner, Paul B Hardy, Anirban Ghoshal, Kenneth H Pearce

bioRxiv· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, Kenneth H Pearce

PLoS One· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
Yuhong Du, William J Bradshaw, Tina M Leisner, Joel K Annor-Gyamfi, Kun Qian, Kenneth H Pearce

J Biol Chem· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fused Tetrahydroquinolines Are Interfering with Your Assay.
Frances M Bashore, Joel Annor-Gyamfi, Yuhong Du, Vittorio Katis, Felix Nwogbo, Kenneth H Pearce

J Med Chem· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis