Publications by authors named "Kenneth V Christensen"

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Development of F/C-Labeled Pyrrolo-Pyridine/Pyrimidine LRRK2 Selective PET Radioligands.
Sangram Nag, Vladimir Stepanov, Akihiro Takano, Ryosuke Arakawa, Marie Svedberg, Kenneth Vielsted Christensen

Pharmaceuticals (Basel)· November 2025

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Buspirone and Zolmitriptan Combination for Dyskinesia: A Randomized, Controlled, Crossover Study.
Peter A LeWitt, Glenn T Stebbins, Kenneth Vielsted Christensen, Riswanto Tan, Anél Pretorius

Mov Disord· March 2024

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Synergistic effect of serotonin 1A and serotonin 1B/D receptor agonists in the treatment of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rats.
Mikael Thomsen, Anca Stoica, Kenneth Vielsted Christensen, Tue Fryland, Jens D Mikkelsen

Exp Neurol· December 2022

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No Detectable Effect on Visual Responses Using Functional MRI in a Rodent Model of α-Synuclein Expression.
Freja Gam Østergaard, Christian Stald Skoven, Alex R Wade, Hartwig R Siebner, Bettina Laursen, Kenneth Vielsted Christensen

eNeuro· July 2021

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Design and Synthesis of Pyrrolo[2,3-]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate.
Douglas S Williamson, Garrick P Smith, Gitte K Mikkelsen, Thomas Jensen, Pamela Acheson-Dossang, Kenneth V Christensen

J Med Chem· July 2021

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Progressive Effects of Sildenafil on Visual Processing in Rats.
Freja Gam Østergaard, Alex R Wade, Hartwig Roman Siebner, Kenneth Vielsted Christensen, Bettina Laursen

Neuroscience· August 2020

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Classification of α-synuclein-induced changes in the AAV α-synuclein rat model of Parkinson's disease using electrophysiological measurements of visual processing.
Freja Gam Østergaard, Marc M Himmelberg, Bettina Laursen, Hartwig R Siebner, Alex R Wade, Kenneth Vielsted Christensen

Sci Rep· July 2020

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Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications.
Michael Aagaard Andersen, Florence Sotty, Poul Henning Jensen, Lassina Badolo, Ross Jeggo, Kenneth Vielsted Christensen

eNeuro· May 2020

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Transcriptome analysis identifies activated signaling pathways and regulated ABC transporters and solute carriers after hyperosmotic stress in renal MDCK I cells.
Rune Nørgaard Rasmussen, Kenneth Vielsted Christensen, René Holm, Carsten Uhd Nielsen

Genomics· December 2019

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Nfat5 is involved in the hyperosmotic regulation of Tmem184b: a putative modulator of ibuprofen transport in renal MDCK I cells.
Rune Nørgaard Rasmussen, Kenneth Vielsted Christensen, René Holm, Carsten Uhd Nielsen

FEBS Open Bio· June 2019

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Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation.
Michael Aagaard Andersen, Kenneth Vielsted Christensen, Lassina Badolo, Garrick Paul Smith, Ross Jeggo

Neurobiol Dis· August 2018

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PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats.
Michael Aagaard Andersen, Karen Malene Wegener, Steen Larsen, Lassina Badolo, Garrick Paul Smith, Kenneth Vielsted Christensen

Toxicology· February 2018

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Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1).
Douglas S Williamson, Garrick P Smith, Pamela Acheson-Dossang, Simon T Bedford, Victoria Chell, Kenneth V Christensen

J Med Chem· November 2017

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A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission.
Jacob Nielsen, Kim Fejgin, Florence Sotty, Vibeke Nielsen, Arne Mørk, Kenneth V Christensen

Transl Psychiatry· November 2017

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The design and SAR of a novel series of 2-aminopyridine based LRRK2 inhibitors.
Garrick P Smith, Lassina Badolo, Victoria Chell, I-Jen Chen, Kenneth Vielsted Christensen

Bioorg Med Chem Lett· September 2017

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Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells.
Kenneth Thirstrup, Justus C Dächsel, Felix S Oppermann, Douglas S Williamson, Garrick P Smith, Kenneth V Christensen

Sci Rep· August 2017

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Asc-1 Transporter Regulation of Synaptic Activity via the Tonic Release of d-Serine in the Forebrain.
Hagit Sason, Jean Marie Billard, Garrick Paul Smith, Hazem Safory, Samah Neame, Kenneth Vielsted Christensen

Cereb Cortex· February 2017

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Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: a study in male mice.
Michael Didriksen, Kim Fejgin, Simon R O Nilsson, Michelle R Birknow, Hannah M Grayton, Kenneth V Christensen

J Psychiatry Neurosci· January 2017

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Abnormal visual gain control in a Parkinson's disease model.
Farinaz Afsari, Kenneth V Christensen, Garrick Paul Smith, Morten Hentzer, Olivia M Nippe

Hum Mol Genet· September 2014

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A mouse model that recapitulates cardinal features of the 15q13.3 microdeletion syndrome including schizophrenia- and epilepsy-related alterations.
Kim Fejgin, Jacob Nielsen, Michelle R Birknow, Jesper F Bastlund, Vibeke Nielsen, Kenneth V Christensen

Biol Psychiatry· July 2014

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Preexercise energy drink consumption does not improve endurance cycling performance but increases lactate, monocyte, and interleukin-6 response.
Melody D Phillips, Kelyn S Rola, Kenneth V Christensen, Jacob W Ross, Joel B Mitchell

J Strength Cond Res· May 2014

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Glucocorticoid receptor and myocyte enhancer factor 2 cooperate to regulate the expression of c-JUN in a neuronal context.
Niels Speksnijder, Kenneth V Christensen, Michael Didriksen, E Ronald De Kloet, Nicole A Datson

J Mol Neurosci· September 2012

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Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus.
Xiaole Wang, Helle Hald, Heidi A Ernst, Jan Egebjerg, Kenneth V Christensen

Protein Expr Purif· June 2010

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Support for a bipolar affective disorder susceptibility locus on chromosome 12q24.3.
Henriette Nørmølle Buttenschøn, Leslie Foldager, Tracey J Flint, Inger Marie L Olsen, Thomas Deleuran, Kenneth V Christensen

Psychiatr Genet· June 2010

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Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled rats.
Kenneth V Christensen, Henrik Leffers, William P Watson, Connie Sánchez, Pekka Kallunki

BMC Neurosci· January 2010

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