Publications by authors named "Kenneth W Harder"

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Transfection Potency of Lipid Nanoparticles Containing mRNA Depends on Relative Loading Levels.
Suiyang Liao, Shuangyu Wang, Abishek Wadhwa, Alexandra Birkenshaw, Kevin Fox, Kenneth W Harder

ACS Appl Mater Interfaces· January 2025

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Considerations on the Design of Lipid-based mRNA Vaccines Against Cancer.
Sofie Meulewaeter, Yao Zhang, Abishek Wadhwa, Kevin Fox, Ine Lentacker, Kenneth W Harder

J Mol Biol· January 2024

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Tumor-derived GCSF Alters Tumor and Systemic Immune System Cell Subset Composition and Signaling.
Israel Matos, Maunish Barvalia, Manreet K Chehal, A Gordon Robertson, Iva Kulic, Kenneth W Harder

Cancer Res Commun· March 2023

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An End-to-End Workflow for Interrogating Tumor-Infiltrating Myeloid Cells Using Mass Cytometry.
Maunish Barvalia, Kenneth W Harder

Methods Mol Biol· June 2022

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Cutting Edge: Intestinal Mucus Limits the Clonal Deletion of Developing T Cells Specific for an Oral Antigen.
Kevin Tsai, Yu-Hsuan Huang, Caixia Ma, Troy A Baldwin, Kenneth W Harder

J Immunol· July 2020

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Deep Phenotyping by Mass Cytometry and Single-Cell RNA-Sequencing Reveals LYN-Regulated Signaling Profiles Underlying Monocyte Subset Heterogeneity and Lifespan.
Morgan E Roberts, Maunish Barvalia, Jessica A F D Silva, Rachel A Cederberg, William Chu, Kenneth W Harder

Circ Res· May 2020

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2B4-SAP signaling is required for the priming of naive CD8 T cells by antigen-expressing B cells and B lymphoma cells.
Yu-Hsuan Huang, Kevin Tsai, Sara Y Tan, Sohyeong Kang, Mandy L Ford, Kenneth W Harder

Oncoimmunology· December 2016

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The orphan nuclear receptor ROR alpha and group 3 innate lymphoid cells drive fibrosis in a mouse model of Crohn's disease.
Bernard C Lo, Matthew J Gold, Michael R Hughes, Frann Antignano, Yanet Valdez, Kenneth W Harder

Sci Immunol· September 2016

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The orphan nuclear receptor RORα and group 3 innate lymphoid cells drive fibrosis in a mouse model of Crohn's disease.
Bernard C Lo, Matthew J Gold, Michael R Hughes, Frann Antignano, Yanet Valdez, Kenneth W Harder

Sci Immunol· September 2016

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Lyn deficiency leads to increased microbiota-dependent intestinal inflammation and susceptibility to enteric pathogens.
Morgan E Roberts, Jennifer L Bishop, Xueling Fan, Jennifer L Beer, Winnie W S Kum, Kenneth W Harder

J Immunol· November 2014

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Dysregulated hematopoiesis caused by mammary cancer is associated with epigenetic changes and hox gene expression in hematopoietic cells.
Alexander Sio, Manreet K Chehal, Kevin Tsai, Xueling Fan, Morgan E Roberts, Kenneth W Harder

Cancer Res· October 2013

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Phosphatidylinositol-3 kinase activity in B cells is negatively regulated by Lyn tyrosine kinase.
Yuekang Xu, Nicholas D Huntington, Kenneth W Harder, Harshal Nandurkar, Margaret L Hibbs

Immunol Cell Biol· October 2012

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Genetic interdependence of Lyn and negative regulators of B cell receptor signaling in autoimmune disease development.
Evelyn Tsantikos, Mhairi J Maxwell, Nicole Kountouri, Kenneth W Harder, David M Tarlinton

J Immunol· August 2012

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Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells.
Danielle L Krebs, Manreet K Chehal, Alexander Sio, Nicholas D Huntington, Mei Lin Da, Kenneth W Harder

J Immunol· May 2012

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The role of the Src family kinase Lyn in the immunomodulatory activities of cathelicidin peptide LL-37 on monocytic cells.
Anastasia Nijnik, Jelena Pistolic, Patricia Cho, Niall C J Filewod, Reza Falsafi, Kenneth W Harder

J Leukoc Biol· April 2012

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Perturbation of the CD4 T cell compartment and expansion of regulatory T cells in autoimmune-prone Lyn-deficient mice.
Evelyn Tsantikos, Cathy Quilici, Kenneth W Harder, Bo Wang, Hong-Jian Zhu

J Immunol· August 2009

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Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.
Marina Tiemi Shio, Stephanie C Eisenbarth, Myriam Savaria, Adrien F Vinet, Marie-Josée Bellemare, Kenneth W Harder

PLoS Pathog· August 2009

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Chronic immunodeficiency in mice lacking RasGRP1 results in CD4 T cell immune activation and exhaustion.
John J Priatel, Xiaoxi Chen, Lauren A Zenewicz, Hao Shen, Kenneth W Harder

J Immunol· August 2007

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Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2.
Bradley K McColl, Karri Paavonen, Tara Karnezis, Nicole C Harris, Natalia Davydova, Kenneth W Harder

FASEB J· April 2007

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Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimulated cells.
Evan Ingley, Jessica R Schneider, Christine J Payne, David J McCarthy, Kenneth W Harder

J Biol Chem· October 2006

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The duplicitous nature of the Lyn tyrosine kinase in growth factor signaling.
Margaret L Hibbs, Kenneth W Harder

Growth Factors· June 2006

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Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity.
Sarah-Jane E Beavitt, Kenneth W Harder, Joanna M Kemp, Jessica Jones, Cathy Quilici

J Immunol· August 2005

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Lyn tyrosine kinase: accentuating the positive and the negative.
Yuekang Xu, Kenneth W Harder, Nicholas D Huntington, Margaret L Hibbs, David M Tarlinton

Immunity· January 2005

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Perturbed myelo/erythropoiesis in Lyn-deficient mice is similar to that in mice lacking the inhibitory phosphatases SHP-1 and SHIP-1.
Kenneth W Harder, Cathy Quilici, Edwina Naik, Melissa Inglese, Nicole Kountouri

Blood· December 2004

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Negative regulation of immunoglobulin E-dependent allergic responses by Lyn kinase.
Sandra Odom, Gregorio Gomez, Martina Kovarova, Yasuko Furumoto, John J Ryan, Kenneth W Harder

J Exp Med· June 2004

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