Publications by authors named "Kenneth W Spitzer"

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Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis.
Thirupura S Shankar, Dinesh K A Ramadurai, Kira Steinhorst, Salah Sommakia, Rachit Badolia, Kenneth W Spitzer

Nat Commun· July 2021

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Location and function of transient receptor potential canonical channel 1 in ventricular myocytes.
Qinghua Hu, Azmi A Ahmad, Thomas Seidel, Chris Hunter, Molly Streiff, Kenneth W Spitzer

J Mol Cell Cardiol· February 2020

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pH recovery from a proton load in rat cardiomyocytes: effects of chronic exercise.
Vennetia R Danes, Josephine Anthony, Kaveh Rayani, Kenneth W Spitzer, Glen F Tibbits

Am J Physiol Heart Circ Physiol· February 2018

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Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission.
Kensuke Tsushima, Heiko Bugger, Adam R Wende, Jamie Soto, Gregory A Jenson, Kenneth W Spitzer

Circ Res· January 2018

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Blockade of CaMKII depresses conduction preferentially in the right ventricular outflow tract and promotes ischemic ventricular fibrillation in the rabbit heart.
Mark Warren, Katie J Sciuto, Tyson G Taylor, Vivek Garg, Natalia S Torres, Kenneth W Spitzer

Am J Physiol Heart Circ Physiol· April 2017

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Na⁺ ions as spatial intracellular messengers for co-ordinating Ca²⁺ signals during pH heterogeneity in cardiomyocytes.
Pawel Swietach, Kenneth W Spitzer, Richard D Vaughan-Jones

Cardiovasc Res· February 2015

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A near-infrared fluorescent voltage-sensitive dye allows for moderate-throughput electrophysiological analyses of human induced pluripotent stem cell-derived cardiomyocytes.
Angelica Lopez-Izquierdo, Mark Warren, Michael Riedel, Scott Cho, Shuping Lai, Kenneth W Spitzer

Am J Physiol Heart Circ Physiol· November 2014

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Pumping Ca2+ up H+ gradients: a Ca2(+)-H+ exchanger without a membrane.
Pawel Swietach, Chae-Hun Leem, Kenneth W Spitzer, Richard D Vaughan-Jones

J Physiol· August 2014

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Functional and pharmacological analysis of cardiomyocytes differentiated from human peripheral blood mononuclear-derived pluripotent stem cells.
Michael Riedel, Chuanchau J Jou, Shuping Lai, Robert L Lux, Alonso P Moreno, Kenneth W Spitzer

Stem Cell Reports· July 2014

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A modified local control model for Ca2+ transients in cardiomyocytes: junctional flux is accompanied by release from adjacent non-junctional RyRs.
Natalia S Torres, Frank B Sachse, Leighton T Izu, Joshua I Goldhaber, Kenneth W Spitzer

J Mol Cell Cardiol· March 2014

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Mechanical modulation of the transverse tubular system of ventricular cardiomyocytes.
Thomas G McNary, Kenneth W Spitzer, Hilary Holloway, John H B Bridge, Peter Kohl

Prog Biophys Mol Biol· November 2013

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Metabolic determinants of electrical failure in ex-vivo canine model of cardiac arrest: evidence for the protective role of inorganic pyrophosphate.
Junko Shibayama, Tyson G Taylor, Paul W Venable, Nathaniel L Rhodes, Ryan B Gil, Kenneth W Spitzer

PLoS One· September 2013

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Detection of mitochondrial depolarization/recovery during ischaemia--reperfusion using spectral properties of confocally recorded TMRM fluorescence.
Paul W Venable, Tyson G Taylor, Katie J Sciuto, Jerry Zhao, Junko Shibayama, Kenneth W Spitzer

J Physiol· June 2013

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Modulation of ventricular transient outward K⁺ current by acidosis and its effects on excitation-contraction coupling.
Noriko Saegusa, Vivek Garg, Kenneth W Spitzer

Am J Physiol Heart Circ Physiol· June 2013

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Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling.
Pawel Swietach, Jae-Boum Youm, Noriko Saegusa, Chae-Hun Leem, Kenneth W Spitzer

Proc Natl Acad Sci U S A· May 2013

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Platelet-activating factor stimulates sodium-hydrogen exchange in ventricular myocytes.
Yoichi Ajiro, Noriko Saegusa, Wayne R Giles, Diana M Stafforini, Kenneth W Spitzer

Am J Physiol Heart Circ Physiol· December 2011

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Influence of pH on Ca²⁺ current and its control of electrical and Ca²⁺ signaling in ventricular myocytes.
Noriko Saegusa, Emma Moorhouse, Richard D Vaughan-Jones, Kenneth W Spitzer

J Gen Physiol· November 2011

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High-precision recording of the action potential in isolated cardiomyocytes using the near-infrared fluorescent dye di-4-ANBDQBS.
Mark Warren, Kenneth W Spitzer, Bruce W Steadman, Tyler D Rees, Paul Venable

Am J Physiol Heart Circ Physiol· October 2010

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Blebbistatin effectively uncouples the excitation-contraction process in zebrafish embryonic heart.
Chuanchau J Jou, Kenneth W Spitzer, Martin Tristani-Firouzi

Cell Physiol Biochem· June 2010

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Nonanticoagulant heparin reduces myocyte Na+ and Ca2+ loading during simulated ischemia and decreases reperfusion injury.
William H Barry, Xiu Q Zhang, Michael E Halkos, Jakob Vinten-Johansen, Noriko Saegusa, Kenneth W Spitzer

Am J Physiol Heart Circ Physiol· January 2010

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Modeling calcium waves in cardiac myocytes: importance of calcium diffusion.
Pawel Swietach, Kenneth W Spitzer, Richard D Vaughan-Jones

Front Biosci (Landmark Ed)· January 2010

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Intracellular pH regulation in heart.
Richard D Vaughan-Jones, Kenneth W Spitzer, Pawel Swietach

J Mol Cell Cardiol· March 2009

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Ca2+-mobility in the sarcoplasmic reticulum of ventricular myocytes is low.
Pawel Swietach, Kenneth W Spitzer, Richard D Vaughan-Jones

Biophys J· August 2008

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Enhanced activity of ventricular Na+-HCO3- cotransport in pressure overload hypertrophy.
Taku Yamamoto, Takeshi Shirayama, Tomohiko Sakatani, Tomosaburo Takahashi, Hideo Tanaka, Kenneth W Spitzer

Am J Physiol Heart Circ Physiol· August 2007

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H+ ion activation and inactivation of the ventricular gap junction: a basis for spatial regulation of intracellular pH.
Pawel Swietach, Alessandra Rossini, Kenneth W Spitzer, Richard D Vaughan-Jones

Circ Res· April 2007

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