Publications by authors named "Pawel Swietach"

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Using Mathematical Modeling of Tumor Metabolism to Predict the Magnitude, Composition, and Hypoxic Interactions of Microenvironment Acidosis.
Alzbeta Hulikova, Pawel Swietach

Bioessays· January 2026

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Lipid cubosome nanoparticles for drug delivery.
Hayley C Parkin, Pawel Swietach, Helen Townley

Nanomedicine (Lond)· December 2025

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Rapid oxygen release from stored red blood cells can be preserved for longer with refined additive solutions.
Julija Rabcuka, Athinoula Meli, Jennifer Jolley, Azhar I Mohamudally, John R Hess, Pawel Swietach

Transfusion· December 2025

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Calcium Regulation of Mitochondrial Metabolism.
Carmen A Mannella, Pawel Swietach, Liron Boyman

Annu Rev Physiol· November 2025

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Hypoxia Increases Sarcolemmal Na/HCO Cotransport Activity via an ERK1/2-Dependent Pathway in Cardiac HL-1 Cell Line.
Gül Şimşek, Pawel Swietach, Hilmi Burak Kandilci

J Cell Physiol· October 2025

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Acidosis attenuates the hypoxic stabilization of HIF-1α by activating lysosomal degradation.
Bobby White, Zhenyi Wang, Matthew Dean, Johanna Michl, Natalia Nieora, Pawel Swietach

J Cell Biol· August 2025

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A Langendorff-heart discovery pipeline demonstrates cardiomyocyte targeting by extracellular vesicles functionalized with beta-blockers using click-chemistry.
Kyung Chan Park, Amir Mashia Jaafari, Christopher Anthony Smith, Althea Rennisa Lobo, Lorenzo Errichelli, Pawel Swietach

J Mol Cell Cardiol· July 2025

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FoxO1-zDHHC4-CD36 S-Acylation Axis Drives Metabolic Dysfunction in Diabetes.
Kaitlyn M J H Dennis, Keshav Gopal, Claudia N Montes Aparicio, Jiashuo Aaron Zhang, Marcos Castro-Guarda, Pawel Swietach

Circ Res· June 2025

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Assessing the kinetics of oxygen-unloading from red cells using FlowScore, a flow-cytometric proxy of the functional quality of blood.
Julija Rabcuka, Peter A Smethurst, Katharina Dammert, Jarob Saker, Gemma Aran, Pawel Swietach

EBioMedicine· January 2025

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The release of GLP-1 from gut L cells is inhibited by low extracellular pH.
Philippa Garbutt, Malgorzata Cyranka, Johanna Michl, Yuko Maejima, Natascia Vedovato, Pawel Swietach

Obesity (Silver Spring)· October 2024

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Innovating cancer drug discovery with refined phenotypic screens.
Zhenyi Wang, Alzbeta Hulikova, Pawel Swietach

Trends Pharmacol Sci· August 2024

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CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH.
Johanna Michl, Yunyi Wang, Stefania Monterisi, Wiktoria Blaszczak, Ryan Beveridge, Pawel Swietach

Cell Rep· July 2024

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Protocol for separating cancer cell subpopulations by metabolic activity using flow cytometry.
Wiktoria Blaszczak, Bobby White, Pawel Swietach

STAR Protoc· June 2024

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What can we learn about acid-base transporters in cancer from studying somatic mutations in their genes?
Bobby White, Pawel Swietach

Pflugers Arch· April 2024

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Carnosine facilitates lysosomal release of inhibitors of T cell surveillance.
Pawel Swietach, Marja Jäättelä, Shari Pillon-Thomas, Ebbe Boedtkjer

Cell Metab· March 2024

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Phenotypic screen of sixty-eight colorectal cancer cell lines identifies CEACAM6 and CEACAM5 as markers of acid resistance.
Johanna Michl, Bobby White, Stefania Monterisi, Walter F Bodmer, Pawel Swietach

Proc Natl Acad Sci U S A· March 2024

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Impaired O2 unloading from stored blood results in diffusion-limited O2 release at tissues: evidence from human kidneys.
Richard Dumbill, Julija Rabcuka, John Fallon, Simon Knight, James Hunter, Pawel Swietach

Blood· February 2024

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Dynamic IL-6R/STAT3 signaling leads to heterogeneity of metabolic phenotype in pancreatic ductal adenocarcinoma cells.
Wiktoria Blaszczak, Bobby White, Stefania Monterisi, Pawel Swietach

Cell Rep· January 2024

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How protons pave the way to aggressive cancers.
Pawel Swietach, Ebbe Boedtkjer, Stine Falsig Pedersen

Nat Rev Cancer· December 2023

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Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation.
Kyung Chan Park, Nicholas T Crump, Niamh Louwman, Steve Krywawych, Yuen Jian Cheong, Pawel Swietach

Nat Cardiovasc Res· December 2023

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Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2.
Johanna Michl, Stefania Monterisi, Bobby White, Wiktoria Blaszczak, Alzbeta Hulikova, Pawel Swietach

Cell Rep· June 2023

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Permeability and driving force: why is difficult to control glycolytic flux by blocking lactate transporters?
Wiktoria Blaszczak, Pawel Swietach

Oncotarget· January 2023

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Autoregulation of H/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic acid production.
Wiktoria Blaszczak, Hannah Williams, Pawel Swietach

Br J Cancer· October 2022

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Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes.
Stefania Monterisi, Johanna Michl, Alzbeta Hulikova, Jana Koth, Esther M Bridges, Pawel Swietach

Elife· September 2022

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Proton export upregulates aerobic glycolysis.
Shonagh Russell, Liping Xu, Yoonseok Kam, Dominique Abrahams, Bryce Ordway, Pawel Swietach

BMC Biol· July 2022

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