Publications by authors named "Kerry Tyson"

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A computational method for predicting the aggregation propensity of IgG1 and IgG4(P) mAbs in common storage buffers.
James T Heads, Sebastian Kelm, Kerry Tyson, Alastair D G Lawson

MAbs· November 2022

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Interleukin (IL)-12 and IL-18 Synergize to Promote MAIT Cell IL-17A and IL-17F Production Independently of IL-23 Signaling.
Suzanne Cole, Janine Murray, Catherine Simpson, Remi Okoye, Kerry Tyson

Front Immunol· June 2021

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Electrostatic interactions modulate the differential aggregation propensities of IgG1 and IgG4P antibodies and inform charged residue substitutions for improved developability.
James T Heads, Richard Lamb, Sebastian Kelm, Ralph Adams, Peter Elliott, Kerry Tyson

Protein Eng Des Sel· December 2019

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Generation of two high affinity anti-mouse FcRn antibodies: Inhibition of IgG recycling in wild type mice and effect in a mouse model of immune thrombocytopenia.
Bryan Smith, Louis Christodoulou, Alison Clargo, Alison Eddleston, Kevin Greenslade, Kerry Tyson

Int Immunopharmacol· January 2019

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Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau.
Jean-Philippe Courade, Rachel Angers, Georges Mairet-Coello, Nathalie Pacico, Kerry Tyson

Acta Neuropathol· November 2018

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Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration.
Bryan Smith, Andrea Kiessling, Rocio Lledo-Garcia, Kate L Dixon, Louis Christodoulou, Kerry Tyson

MAbs· October 2018

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Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss.
Akilan Krishnamurthy, Vijay Joshua, Aase Haj Hensvold, Tao Jin, Meng Sun, Kerry Tyson

Ann Rheum Dis· April 2016

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Corrigendum to "The Discovery, Engineering and Characterisation of a Highly Potent Anti-Human IL-13 Fab Fragment Designed for Administration by Inhalation" [J. Mol. Biol. 425 (2013), 577-593].
Daniel Lightwood, Victoria O'Dowd, Bruce Carrington, Vaclav Veverka, Mark D Carr, Kerry Tyson

J Mol Biol· June 2013

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A mixture of functionally oligoclonal humanized monoclonal antibodies that neutralize Clostridium difficile TcdA and TcdB with high levels of in vitro potency shows in vivo protection in a hamster infection model.
Nicola L Davies, Joanne E Compson, Brendon Mackenzie, Victoria L O'Dowd, Amanda K F Oxbrow, Kerry L Tyson

Clin Vaccine Immunol· March 2013

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The discovery, engineering and characterisation of a highly potent anti-human IL-13 fab fragment designed for administration by inhalation.
Daniel Lightwood, Victoria O'Dowd, Bruce Carrington, Vaclav Veverka, Mark D Carr, Kerry Tyson

J Mol Biol· February 2013

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Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro.
Paul J Adam, Joanne Berry, Julie A Loader, Kerry L Tyson, Graham Craggs

Mol Cancer Res· September 2003

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Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification.
Kerry L Tyson, Joanne L Reynolds, Rosamund McNair, Qiuping Zhang, Peter L Weissberg

Arterioscler Thromb Vasc Biol· March 2003

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Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer.
Paul J Adam, Robert Boyd, Kerry L Tyson, Graham C Fletcher, Alasdair Stamps

J Biol Chem· February 2003

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Heterogeneity of gene expression in human atheroma unmasked using cDNA representational difference analysis.
Kerry L Tyson, Peter L Weissberg, Catherine M Shanahan

Physiol Genomics· May 2002

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Hyaluronidase gene profiling and role of hyal-1 overexpression in an orthotopic model of prostate cancer.
Sonal Patel, Paul R Turner, Colin Stubberfield, Eleanor Barry, Christian R Rohlff, Kerry Tyson

Int J Cancer· February 2002

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