Publications by authors named "Kerstin Haase"

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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes.
Stefan C Dentro, Ignaty Leshchiner, Kerstin Haase, Maxime Tarabichi, Jeff Wintersinger, Amit G Deshwar, Kaixian Yu, Yulia Rubanova, Geoff Macintyre, Jonas Demeulemeester

Cell· April 2021

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Mutational signatures associated with tobacco smoking in human cancer.
Ludmil B Alexandrov, Young Seok Ju, Kerstin Haase, Peter Van Loo, Iñigo Martincorena, Serena Nik-Zainal, Yasushi Totoki, Akihiro Fujimoto, Hidewaki Nakagawa, Tatsuhiro Shibata

Science· November 2016

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Investigating genetic modifications to enhance L1CAM-CAR T cell migration in solid tumors in a 3D bioprinted neuroblastoma model.
Lena Andersch, Laura Grunewald, Maria Stecklum, Filippos Klironomos, Kerstin Haase

Front Immunol· December 2025

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Clues to why the weight-loss condition cachexia arises when cancer occurs.
Kerstin Haase, Mariam Jamal-Hanjani

Nature· October 2025

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Cancer-Associated Cachexia: Bridging Clinical Findings with Mechanistic Insights in Human Studies.
Kexin Koh, Rachel Scott, Elizabeth M Cespedes Feliciano, Tobias Janowitz, Marcus D Goncalves, Kerstin Haase

Cancer Discov· August 2025

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Functional liver genomics identifies hepatokines promoting wasting in cancer cachexia.
Doris Kaltenecker, Søren Fisker Schmidt, Peter Weber, Anne Loft, Pauline Morigny, Kerstin Haase

Cell· August 2025

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Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction.
Adriana Salcedo, Maxime Tarabichi, Alex Buchanan, Shadrielle M G Espiritu, Hongjiu Zhang, Kerstin Haase

Nat Biotechnol· April 2025

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Reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data using Decoil.
Mădălina Giurgiu, Nadine Wittstruck, Elias Rodriguez-Fos, Rocío Chamorro González, Lotte Brückner, Kerstin Haase

Genome Res· October 2024

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Copy-number dosage regulates telomere maintenance and disease-associated pathways in neuroblastoma.
Martin Burkert, Eric Blanc, Nina Thiessen, Christiane Weber, Joern Toedling, Kerstin Haase

iScience· October 2024

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Intercellular extrachromosomal DNA copy-number heterogeneity drives neuroblastoma cell state diversity.
Maja C Stöber, Rocío Chamorro González, Lotte Brückner, Thomas Conrad, Nadine Wittstruck, Kerstin Haase

Cell Rep· September 2024

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Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models.
Fabian F Pusch, Heathcliff Dorado García, Robin Xu, Dennis Gürgen, Yi Bei, Kerstin Haase

Mol Cancer Ther· April 2024

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Passenger Gene Coamplifications Create Collateral Therapeutic Vulnerabilities in Cancer.
Yi Bei, Luca Bramé, Marieluise Kirchner, Raphaela Fritsche-Guenther, Severine Kunz, Kerstin Haase

Cancer Discov· March 2024

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Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine.
Anssi Nurminen, Serafiina Jaatinen, Sinja Taavitsainen, Gunilla Högnäs, Tom Lesluyes, Kerstin Haase

Genome Med· October 2023

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Mutational topography reflects clinical neuroblastoma heterogeneity.
Elias Rodriguez-Fos, Mercè Planas-Fèlix, Martin Burkert, Montserrat Puiggròs, Joern Toedling, Kerstin Haase

Cell Genom· October 2023

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Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity.
Thomas B K Watkins, Emma C Colliver, Matthew R Huska, Tom L Kaufmann, Emilia L Lim, Kerstin Haase

PLoS Comput Biol· October 2023

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Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Rocío Chamorro González, Thomas Conrad, Maja C Stöber, Robin Xu, Mădălina Giurgiu, Kerstin Haase

Nat Genet· May 2023

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Author Correction: The evolutionary history of 2,658 cancers.
Moritz Gerstung, Clemency Jolly, Ignaty Leshchiner, Stefan C Dentro, Santiago Gonzalez, Kerstin Haase

Nature· February 2023

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Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.
Sofia Birkeälv, Mark Harland, Larissa Satiko Alcantara Sekimoto Matsuyama, Mamun Rashid, Ishan Mehta, Kerstin Haase

J Pathol· January 2023

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MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution.
Tom L Kaufmann, Marina Petkovic, Thomas B K Watkins, Emma C Colliver, Sofya Laskina, Kerstin Haase

Genome Biol· November 2022

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Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Heathcliff Dorado García, Fabian Pusch, Yi Bei, Jennifer von Stebut, Glorymar Ibáñez, Kerstin Haase

Nat Commun· July 2022

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Signatures of copy number alterations in human cancer.
Christopher D Steele, Ammal Abbasi, S M Ashiqul Islam, Amy L Bowes, Azhar Khandekar, Kerstin Haase

Nature· June 2022

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A pan-cancer compendium of chromosomal instability.
Ruben M Drews, Barbara Hernando, Maxime Tarabichi, Kerstin Haase, Tom Lesluyes

Nature· June 2022

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Genomic Evolution and Personalized Therapy of an Infantile Fibrosarcoma Harboring an Oncogenic Fusion.
Anne Thorwarth, Kerstin Haase, Claudia Röefzaad, Kristian W Pajtler, Kathrin Schramm

JCO Precis Oncol· May 2022

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Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions.
Karin Schmelz, Joern Toedling, Matt Huska, Maja C Cwikla, Louisa-Marie Kruetzfeldt, Kerstin Haase

Nat Commun· November 2021

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Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture.
Eva G Álvarez, Jonas Demeulemeester, Paula Otero, Clemency Jolly, Daniel García-Souto, Kerstin Haase

Nat Commun· November 2021

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Subclone Eradication Analysis Identifies Targets for Enhanced Cancer Therapy and Reveals L1 Retrotransposition as a Dynamic Source of Cancer Heterogeneity.
Kirsi Ketola, Heidi Kaljunen, Sinja Taavitsainen, Roosa Kaarijärvi, Emmi Järvelä, Kerstin Haase

Cancer Res· October 2021

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