Publications by authors named "Kevin Bacon"

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Case report: Long-term follow-up of patients who received a FimCH vaccine for prevention of recurrent urinary tract infections caused by antibiotic resistant Enterobacteriaceae: a case report series.
Elise Perer, Helen Stacey, Terri Eichorn, Heidi Hughey, Julie Lawrence, Kevin Bacon

Front Immunol· March 2024

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Lysophosphatidic acid receptor 1 antagonist (EPGN2154) causes regression of NASH in preclinical NASH models.
Jashdeep Bhattacharjee, Graham Beaton, Satheesh B Ravula, Suk Joong Lee, Kevin B Bacon

Hepatol Commun· December 2023

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Reduced AIBP expression in bronchial epithelial cells of asthmatic patients: Potential therapeutic target.
Marina Miller, Alexa K Pham, Ayelet Gonen, Juliana M Navia-Pelaez, Katherine Xia, Kevin Bacon

Clin Exp Allergy· August 2022

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Targeting MAP3K19 prevents human lung myofibroblast activation both in vitro and in a humanized SCID model of idiopathic pulmonary fibrosis.
Isabelle C Jones, Milena S Espindola, Rohan Narayanan, Ana L Coelho, David M Habiel, Kevin B Bacon

Sci Rep· December 2019

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MAP3K19 Is a Novel Regulator of TGF-β Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis.
Stefen A Boehme, Karin Franz-Bacon, Danielle N DiTirro, Tai Wei Ly, Kevin B Bacon

PLoS One· July 2017

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MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction.
Stefen A Boehme, Karin Franz-Bacon, John Ludka, Danielle N DiTirro, Tai Wei Ly, Kevin B Bacon

PLoS One· July 2017

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Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4.
Sven Golfier, Shinichi Kondo, Tobias Schulze, Tomomi Takeuchi, Galya Vassileva, Kevin B Bacon

FASEB J· December 2010

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Murine bone marrow-derived mast cells express chemoattractant receptor-homologous molecule expressed on T-helper class 2 cells (CRTh2).
Stefen A Boehme, Karin Franz-Bacon, Edward P Chen, Tai Wei Ly, Yuko Kawakami, Kevin B Bacon

Int Immunol· June 2009

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A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
Stefen A Boehme, Karin Franz-Bacon, Edward P Chen, Roman Sásik, L James Sprague, Kevin B Bacon

Int Immunol· January 2009

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Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms.
Stefen A Boehme, Edward P Chen, Karin Franz-Bacon, Roman Sásik, L James Sprague, Kevin B Bacon

Int Immunol· January 2009

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CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation.
Nicholas W Lukacs, Aaron A Berlin, Karin Franz-Bacon, Roman Sásik, L James Sprague, Kevin B Bacon

Am J Physiol Lung Cell Mol Physiol· November 2008

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Inhibition of eosinophilia in vivo by a small molecule inhibitor of very late antigen (VLA)-4.
Hiromi Okigami, Keisuke Takeshita, Masaomi Tajimi, Hiroshi Komura, Markus Albers, Kevin B Bacon

Eur J Pharmacol· March 2007

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Cinnabaramides A-G: analogues of lactacystin and salinosporamide from a terrestrial streptomycete.
Marc Stadler, Jens Bitzer, Anke Mayer-Bartschmid, Hartwig Müller, Jordi Benet-Buchholz, Kevin B Bacon

J Nat Prod· February 2007

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PAR-2 deficient CD4+ T cells exhibit downregulation of IL-4 and upregulation of IFN-gamma after antigen challenge in mice.
Michitaka Shichijo, Shinichi Kondo, Mina Ishimori, Shinichi Watanabe, Heidi Helin, Kevin B Bacon

Allergol Int· September 2006

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CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses.
Hiromi Sugimoto, Michitaka Shichijo, Mitsuhiro Okano, Kevin B Bacon

Eur J Pharmacol· November 2005

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Small-molecule CRTH2 antagonists for the treatment of allergic inflammation: an overview.
Tai Wei Ly, Kevin B Bacon

Expert Opin Investig Drugs· July 2005

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A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity.
Karl Ziegelbauer, Florian Gantner, Nicholas W Lukacs, Aaron Berlin, Kinji Fuchikami, Kevin B Bacon

Br J Pharmacol· May 2005

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Growth inhibition of multiple myeloma cells by a novel IkappaB kinase inhibitor.
Takaomi Sanda, Shinsuke Iida, Hiroka Ogura, Kaori Asamitsu, Toshiki Murata, Kevin B Bacon

Clin Cancer Res· March 2005

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Synthesis and structure-activity relationships of novel IKK-beta inhibitors. Part 2: Improvement of in vitro activity.
Toshiki Murata, Mitsuyuki Shimada, Hiroshi Kadono, Sachiko Sakakibara, Takashi Yoshino, Kevin B Bacon

Bioorg Med Chem Lett· August 2004

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Synthesis and structure-activity relationships of novel IKK-beta inhibitors. Part 3: Orally active anti-inflammatory agents.
Toshiki Murata, Mitsuyuki Shimada, Sachiko Sakakibara, Takashi Yoshino, Tsutomu Masuda, Kevin B Bacon

Bioorg Med Chem Lett· August 2004

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Critical role of L-selectin and histamine H4 receptor in zymosan-induced neutrophil recruitment from the bone marrow: comparison with carrageenan.
Keisuke Takeshita, Kevin B Bacon, Florian Gantner

J Pharmacol Exp Ther· July 2004

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CRTH2 is a prominent effector in contact hypersensitivity-induced neutrophil inflammation.
Keisuke Takeshita, Tsugiko Yamasaki, Koichi Nagao, Hiromi Sugimoto, Michitaka Shichijo, Kevin B Bacon

Int Immunol· July 2004

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Essential role of MHC II-independent CD4+ T cells, IL-4 and STAT6 in contact hypersensitivity induced by fluorescein isothiocyanate in the mouse.
Keisuke Takeshita, Tsugiko Yamasaki, Shizuo Akira, Florian Gantner, Kevin B Bacon

Int Immunol· May 2004

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Discovery and evaluation of terephthalic acid derivatives as potent alpha4beta1 integrin antagonists.
Gerhard Müller, Markus Albers, Gerhard Hessler, Thomas E Lehmann, Hiromi Okigami, Kevin Bacon

J Enzyme Inhib Med Chem· August 2003

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A versatile high-throughput screen for inhibitors of lipid kinase activity: development of an immobilized phospholipid plate assay for phosphoinositide 3-kinase gamma.
Kinji Fuchikami, Hiroko Togame, Atsuko Sagara, Tomoko Satoh, Florian Gantner, Kevin B Bacon

J Biomol Screen· October 2002

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