Publications by authors named "Kevin Burris"

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Development of an Electrophysiological Assay for Kv7 Modulators on IonWorks Barracuda.
Benjamin Wilenkin, Kevin D Burris, Brian J Eastwood, Emanuele Sher, Andrew C Williams

Assay Drug Dev Technol· October 2019

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Modulation of TARP 8-Containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain.
Kelly L Knopp, Rosa Maria A Simmons, Wenhong Guo, Benjamin L Adams, Kevin M Gardinier, Kevin D Burris

J Pharmacol Exp Ther· June 2019

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Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism.
Akihiko S Kato, Kevin D Burris, Kevin M Gardinier, Douglas L Gernert, Warren J Porter

Nat Med· December 2016

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An Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors.
Enrique Jambrina, Rok Cerne, Emery Smith, Louis Scampavia, Maria Cuadrado, Kevin D Burris

J Biomol Screen· June 2016

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JBS Special Issue: Innovative Screening Methodologies to Identify New Compounds for the Treatment of Central Nervous System Disorders.
Kevin D Burris, Steven I Dworetzky

J Biomol Screen· June 2016

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Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8.
Kevin M Gardinier, Douglas L Gernert, Warren J Porter, Jon K Reel, Paul L Ornstein, Kevin D Burris

J Med Chem· May 2016

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Optimization of a High-Throughput Assay for Calcium Channel Modulators on IonWorks Barracuda.
Rok Cerne, Mark Wakulchik, Baolin Li, Kevin D Burris, Birgit T Priest

Assay Drug Dev Technol· March 2016

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IonWorks Barracuda Assay for Assessment of State-Dependent Sodium Channel Modulators.
Rok Cerne, Mark Wakulchik, Michael J Krambis, Kevin D Burris, Birgit T Priest

Assay Drug Dev Technol· March 2016

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Bias analyses of preclinical and clinical D2 dopamine ligands: studies with immediate and complex signaling pathways.
Tarsis F Brust, Michael P Hayes, David L Roman, Kevin D Burris, Val J Watts

J Pharmacol Exp Ther· March 2015

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Drug-induced sensitization of adenylyl cyclase: assay streamlining and miniaturization for small molecule and siRNA screening applications.
Jason M Conley, Tarsis F Brust, Ruqiang Xu, Kevin D Burris, Val J Watts

J Vis Exp· January 2014

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Design, synthesis and evaluation of constrained tetrahydroimidazopyrimidine derivatives as antagonists of corticotropin-releasing factor type 1 receptor (CRF1R).
Vivekananda M Vrudhula, Bireshwar Dasgupta, Sokhom S Pin, Kevin D Burris, Lynn A Balanda

Bioorg Med Chem Lett· March 2010

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Oxime carbamate--discovery of a series of novel FAAH inhibitors.
S Y Sit, Charles M Conway, Kai Xie, Robert Bertekap, Clotilde Bourin, Kevin D Burris

Bioorg Med Chem Lett· February 2010

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Novel inhibitors of fatty acid amide hydrolase.
S Y Sit, Charlie Conway, Robert Bertekap, Kai Xie, Clotilde Bourin, Kevin Burris

Bioorg Med Chem Lett· June 2007

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An orally active corticotropin releasing factor 1 receptor antagonist from 8-aryl-1,3a,7,8-tetraaza-cyclopenta[a]indenes.
Xiaojun Han, Rita Civiello, Sokhom S Pin, Kevin Burris, Lynn A Balanda

Bioorg Med Chem Lett· April 2007

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Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT 2A receptors: functional receptor-binding and in vivo electrophysiological studies.
Arlene D Stark, Shaun Jordan, Kelly A Allers, Robert L Bertekap, Ruoyan Chen, Kevin D Burris

Psychopharmacology (Berl)· February 2007

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Synthesis and structure-activity relationship of imidazo[1,2-a]benzimidazoles as corticotropin-releasing factor 1 receptor antagonists.
Xiaojun Han, Sokhom S Pin, Kevin Burris, Lawrence K Fung, Stella Huang

Bioorg Med Chem Lett· September 2005

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Synthesis, structure-activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists.
Xiaojun Han, Jodi A Michne, Sokhom S Pin, Kevin D Burris, Lynn A Balanda

Bioorg Med Chem Lett· September 2005

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Aripiprazole's low intrinsic activities at human dopamine D2L and D2S receptors render it a unique antipsychotic.
Yoshihiro Tadori, Takashi Miwa, Katsura Tottori, Kevin D Burris, Arlene Stark

Eur J Pharmacol· May 2005

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Mechanism of action of aripiprazole predicts clinical efficacy and a favourable side-effect profile.
Tsuyoshi Hirose, Yasufumi Uwahodo, Sakiko Yamada, Takashi Miwa, Tetsuro Kikuchi, Kevin D Burris

J Psychopharmacol· September 2004

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The novel antipsychotic aripiprazole is a partial agonist at short and long isoforms of D2 receptors linked to the regulation of adenylyl cyclase activity and prolactin release.
Koutoku Aihara, Jun Shimada, Takashi Miwa, Katsura Tottori, Kevin D Burris

Brain Res· April 2004

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Synthesis and SAR exploration of dinapsoline analogues.
Sing-Yuen Sit, Kai Xie, Swanee Jacutin-Porte, Kenneth M Boy, James Seanz, Kevin D Burris

Bioorg Med Chem· February 2004

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2-arylaminothiazoles as high-affinity corticotropin-releasing factor 1 receptor (CRF1R) antagonists: synthesis, binding studies and behavioral efficacy.
Gene M Dubowchik, Jodi A Michne, Dmitry Zuev, Wendy Schwartz, Paul M Scola, Kevin D Burris

Bioorg Med Chem Lett· November 2003

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Diminished catalepsy and dopamine metabolism distinguish aripiprazole from haloperidol or risperidone.
Satoru Nakai, Tsuyoshi Hirose, Yasufumi Uwahodo, Takeshi Imaoka, Hiroshi Okazaki, Kevin D Burris

Eur J Pharmacol· July 2003

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(+)-Dinapsoline: an efficient synthesis and pharmacological profile of a novel dopamine agonist.
Sing-Yuen Sit, Kai Xie, Swanee Jacutin-Porte, Matthew T Taber, Amit G Gulwadi, Kevin D Burris

J Med Chem· August 2002

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