Publications by authors named "Kevin D Foust"

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Novel MECP2 gene therapy is effective in a multicenter study using two mouse models of Rett syndrome and is safe in non-human primates.
Samantha Powers, Shibi Likhite, Kamal K Gadalla, Carlos J Miranda, Amy J Huffenberger, Kevin D Foust

Mol Ther· September 2023

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Retraction Note: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN.
Kevin D Foust, Xueyong Wang, Vicki L McGovern, Lyndsey Braun, Adam K Bevan

Nat Biotechnol· November 2022

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Biodistribution of onasemnogene abeparvovec DNA, mRNA and SMN protein in human tissue.
Gretchen Thomsen, Arthur H M Burghes, Caroline Hsieh, Janet Do, Binh T T Chu, Kevin D Foust

Nat Med· October 2021

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Systemic Gene Therapy for Targeting the CNS.
Sara E Gombash, Kevin D Foust

Methods Mol Biol· October 2016

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Self-Complementary AAV9 Gene Delivery Partially Corrects Pathology Associated with Juvenile Neuronal Ceroid Lipofuscinosis (CLN3).
Megan E Bosch, Amy Aldrich, Rachel Fallet, Jessica Odvody, Maria Burkovetskaya, Kevin D Foust

J Neurosci· September 2016

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Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis.
SungWon Song, Carlos J Miranda, Lyndsey Braun, Kathrin Meyer, Ashley E Frakes, Kevin D Foust

Nat Med· April 2016

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Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA.
Chitra C Iyer, Vicki L McGovern, Jason D Murray, Sara E Gombash, Phillip G Zaworski, Kevin D Foust

Hum Mol Genet· November 2015

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SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA.
Vicki L McGovern, Chitra C Iyer, W David Arnold, Sara E Gombash, Phillip G Zaworski, Kevin D Foust

Hum Mol Genet· October 2015

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SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice.
Sara E Gombash, Christopher J Cowley, Julie A Fitzgerald, Chitra C Iyer, David Fried, Kevin D Foust

Hum Mol Genet· October 2015

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SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice.
Sara E Gombash, Christopher J Cowley, Julie A Fitzgerald, Chitra C Iyer, David Fried, Kevin D Foust

Hum Mol Genet· July 2015

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Endolysosomal Deficits Augment Mitochondria Pathology in Spinal Motor Neurons of Asymptomatic fALS Mice.
Yuxiang Xie, Bing Zhou, Mei-Yao Lin, Shiwei Wang, Kevin D Foust

Neuron· July 2015

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Improving single injection CSF delivery of AAV9-mediated gene therapy for SMA: a dose-response study in mice and nonhuman primates.
Kathrin Meyer, Laura Ferraiuolo, Leah Schmelzer, Lyndsey Braun, Vicki McGovern, Kevin D Foust

Mol Ther· March 2015

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Intravenous injections in neonatal mice.
Sara E Gombash Lampe, Brian K Kaspar, Kevin D Foust

J Vis Exp· November 2014

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Intravenous AAV9 efficiently transduces myenteric neurons in neonate and juvenile mice.
Sara E Gombash, Christopher J Cowley, Julie A Fitzgerald, Jodie C E Hall, Christian Mueller, Kevin D Foust

Front Mol Neurosci· October 2014

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Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.
Ashley E Frakes, Laura Ferraiuolo, Amanda M Haidet-Phillips, Leah Schmelzer, Lyndsey Braun, Kevin D Foust

Neuron· March 2014

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Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS.
Kevin D Foust, Desirée L Salazar, Shibi Likhite, Laura Ferraiuolo, Dara Ditsworth

Mol Ther· December 2013

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Systemic delivery of MeCP2 rescues behavioral and cellular deficits in female mouse models of Rett syndrome.
Saurabh K Garg, Daniel T Lioy, Hélène Cheval, James C McGann, John M Bissonnette, Kevin D Foust

J Neurosci· August 2013

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Targeted delivery of self-complementary adeno-associated virus serotype 9 to the brain, using magnetic resonance imaging-guided focused ultrasound.
Emmanuel Thévenot, Jessica F Jordão, Meaghan A O'Reilly, Kelly Markham, Ying-Qi Weng, Kevin D Foust

Hum Gene Ther· November 2012

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A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse.
Paul N Porensky, Chalermchai Mitrpant, Vicki L McGovern, Adam K Bevan, Kevin D Foust

Hum Mol Genet· April 2012

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Adeno-associated virus serotype 9 transduction in the central nervous system of nonhuman primates.
Lluis Samaranch, Ernesto A Salegio, Waldy San Sebastian, Adrian P Kells, Kevin D Foust

Hum Gene Ther· April 2012

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Recombinant AAV delivery to the central nervous system.
Olivier Bockstael, Kevin D Foust, Brian Kaspar, Liliane Tenenbaum

Methods Mol Biol· March 2012

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Systemic gene delivery in large species for targeting spinal cord, brain, and peripheral tissues for pediatric disorders.
Adam K Bevan, Sandra Duque, Kevin D Foust, Pablo R Morales, Lyndsey Braun

Mol Ther· November 2011

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Astrocytes from familial and sporadic ALS patients are toxic to motor neurons.
Amanda M Haidet-Phillips, Mark E Hester, Carlos J Miranda, Kathrin Meyer, Lyndsey Braun, Kevin D Foust

Nat Biotechnol· August 2011

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A role for glia in the progression of Rett's syndrome.
Daniel T Lioy, Saurabh K Garg, Caitlin E Monaghan, Jacob Raber, Kevin D Foust

Nature· June 2011

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Early heart failure in the SMNDelta7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery.
Adam K Bevan, Kirk R Hutchinson, Kevin D Foust, Lyndsey Braun, Vicki L McGovern

Hum Mol Genet· October 2010

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