Publications by authors named "Kevin Eade"

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Cell-based regenerative therapy for retinal diseases: challenges and emerging bioengineering strategies.
Yasuaki Iwama, Tomohiro Masuda, Ava Maeyama, Kevin T Eade, Martin Friedlander

Regen Ther· December 2025

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Erucamide regulates retinal neurovascular crosstalk.
Guoqin Wei, Shreyosree Chatterjee, Qinglin Yang, Sanahan Vijayakumar, Daisuke Ogasawara, Kevin Eade

bioRxiv· September 2025

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Neuroprotective properties of ciliary neurotrophic factor in the retina for the treatment of macular telangiectasia type 2.
Arne Nystuen, Eugene Gonzalez-Lopez, Konrad A Kauper, Kevin Eade, Thomas M Aaberg

Cytokine Growth Factor Rev· August 2025

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Retinal pigment epithelial cells reduce vascular leak and proliferation in retinal neovessels.
Simone Tzaridis, Edith Aguilar, Michael I Dorrell, Martin Friedlander, Kevin T Eade

Angiogenesis· November 2024

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Integrating human iPSC-derived macrophage progenitors into retinal organoids to generate a mature retinal microglial niche.
Ayumi Usui-Ouchi, Sarah Giles, Sarah Harkins-Perry, Elizabeth A Mills, Roberto Bonelli, Kevin T Eade

Glia· October 2023

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Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity.
Jessica D Rosarda, Sarah Giles, Sarah Harkins-Perry, Elizabeth A Mills, Martin Friedlander, Kevin T Eade

Nat Commun· July 2023

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iPSC-derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function.
Kevin T Eade, Brendan Robert E Ansell, Sarah Giles, Regis Fallon, Sarah Harkins-Perry

J Clin Invest· May 2023

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Deletion of Tgfβ signal in activated microglia prolongs hypoxia-induced retinal neovascularization enhancing Igf1 expression and retinal leukostasis.
Ayumi Usui-Ouchi, Kevin Eade, Sarah Giles, Yoichiro Ideguchi, Yasuo Ouchi

Glia· September 2022

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Cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease in human retina and retinal organoids.
Eric D Thomas, Andrew E Timms, Sarah Giles, Sarah Harkins-Perry, Pin Lyu, Kevin Eade

Dev Cell· March 2022

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Toxicity Screens in Human Retinal Organoids for Pharmaceutical Discovery.
Kevin Eade, Sarah Giles, Sarah Harkins-Perry, Martin Friedlander

J Vis Exp· March 2021

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Serine biosynthesis defect due to haploinsufficiency of PHGDH causes retinal disease.
Kevin Eade, Marin L Gantner, Joseph A Hostyk, Takayuki Nagasaki, Sarah Giles

Nat Metab· March 2021

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Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy.
Marin L Gantner, Kevin Eade, Martina Wallace, Michal K Handzlik, Regis Fallon

N Engl J Med· October 2019

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Diverse reprogramming codes for neuronal identity.
Rachel Tsunemoto, Sohyon Lee, Attila Szűcs, Pavel Chubukov, Irina Sokolova, Kevin T Eade

Nature· May 2018

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Forward engineering neuronal diversity using direct reprogramming.
Rachel K Tsunemoto, Kevin T Eade, Joel W Blanchard, Kristin K Baldwin

EMBO J· June 2015

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Selective conversion of fibroblasts into peripheral sensory neurons.
Joel W Blanchard, Kevin T Eade, Attila Szűcs, Valentina Lo Sardo, Rachel K Tsunemoto

Nat Neurosci· January 2015

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Developmental transcriptional networks are required to maintain neuronal subtype identity in the mature nervous system.
Kevin T Eade, Hailey A Fancher, Marc S Ridyard, Douglas W Allan

PLoS Genet· February 2013

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Neuronal phenotype in the mature nervous system is maintained by persistent retrograde bone morphogenetic protein signaling.
Kevin T Eade, Douglas W Allan

J Neurosci· March 2009

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