Publications by authors named "Kevin Ebata"

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Preclinical characterization of pirtobrutinib, a highly selective, noncovalent (reversible) BTK inhibitor.
Eliana B Gomez, Kevin Ebata, Hetal S Randeria, Mary S Rosendahl, E Peder Cedervall

Blood· July 2023

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Author Correction: The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers.
Ezra Y Rosen, Helen H Won, Youyun Zheng, Emiliano Cocco, Duygu Selcuklu, Kevin Ebata

Nat Commun· April 2022

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The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers.
Ezra Y Rosen, Helen H Won, Youyun Zheng, Emiliano Cocco, Duygu Selcuklu, Kevin Ebata

Nat Commun· March 2022

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Mechanisms of Resistance to Noncovalent Bruton's Tyrosine Kinase Inhibitors.
Eric Wang, Xiaoli Mi, Meghan C Thompson, Skye Montoya, Ryan Q Notti, Kevin Ebata

N Engl J Med· February 2022

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Pirtobrutinib in relapsed or refractory B-cell malignancies (BRUIN): a phase 1/2 study.
Anthony R Mato, Nirav N Shah, Wojciech Jurczak, Chan Y Cheah, John M Pagel, Kevin Ebata

Lancet· March 2021

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Overcoming MET-Dependent Resistance to Selective RET Inhibition in Patients with RET Fusion-Positive Lung Cancer by Combining Selpercatinib with Crizotinib.
Ezra Y Rosen, Melissa L Johnson, Sarah E Clifford, Romel Somwar, Jennifer F Kherani, Kevin Ebata

Clin Cancer Res· January 2021

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Efficacy of Selpercatinib in Fusion-Positive Non-Small-Cell Lung Cancer.
Alexander Drilon, Geoffrey R Oxnard, Daniel S W Tan, Herbert H F Loong, Melissa Johnson, Kevin Ebata

N Engl J Med· August 2020

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Efficacy of Selpercatinib in -Altered Thyroid Cancers.
Lori J Wirth, Eric Sherman, Bruce Robinson, Benjamin Solomon, Hyunseok Kang, Kevin Ebata

N Engl J Med· August 2020

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RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies.
Benjamin J Solomon, Lavinia Tan, Jessica J Lin, Stephen Q Wong, Sebastian Hollizeck, Kevin Ebata

J Thorac Oncol· April 2020

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Author Correction: Maternal vitamin C regulates reprogramming of DNA methylation and germline development.
Stephanie P DiTroia, Michelle Percharde, Marie-Justine Guerquin, Estelle Wall, Evelyne Collignon, Kevin T Ebata

Nature· December 2019

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Resistance to TRK inhibition mediated by convergent MAPK pathway activation.
Emiliano Cocco, Alison M Schram, Amanda Kulick, Sandra Misale, Helen H Won, Kevin Ebata

Nat Med· September 2019

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Maternal vitamin C regulates reprogramming of DNA methylation and germline development.
Stephanie P DiTroia, Michelle Percharde, Marie-Justine Guerquin, Estelle Wall, Evelyne Collignon, Kevin T Ebata

Nature· September 2019

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Emergence and Targeting of Acquired and Hereditary Resistance to Multikinase RET Inhibition in Patients With RET-Altered Cancer.
Lori J Wirth, Takashi Kohno, Hibiki Udagawa, Shingo Matsumoto, Genichiro Ishii, Kevin Ebata

JCO Precis Oncol· September 2019

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ETV6-NTRK3 induces aggressive acute lymphoblastic leukemia highly sensitive to selective TRK inhibition.
Kathryn G Roberts, Laura J Janke, Yaqi Zhao, Aman Seth, Jing Ma, Kevin Ebata

Blood· August 2018

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Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies.
Justin Taylor, Dean Pavlick, Akihide Yoshimi, Christina Marcelus, Stephen S Chung, Kevin Ebata

J Clin Invest· August 2018

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Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study.
Theodore W Laetsch, Steven G DuBois, Leo Mascarenhas, Brian Turpin, Noah Federman, Kevin T Ebata

Lancet Oncol· May 2018

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Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.
Alexander Drilon, Theodore W Laetsch, Shivaani Kummar, Steven G DuBois, Ulrik N Lassen, Kevin Ebata

N Engl J Med· February 2018

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Vitamin C induces specific demethylation of H3K9me2 in mouse embryonic stem cells via Kdm3a/b.
Kevin T Ebata, Kathryn Mesh, Shichong Liu, Misha Bilenky, Alexander Fekete

Epigenetics Chromatin· October 2017

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A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors.
Alexander Drilon, Ramamoorthy Nagasubramanian, James F Blake, Nora Ku, Brian B Tuch, Kevin Ebata

Cancer Discov· September 2017

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Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.
Kathryn Blaschke, Kevin T Ebata, Mohammad M Karimi, Jorge A Zepeda-Martínez, Preeti Goyal

Nature· August 2013

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Bivalent chromatin marks developmental regulatory genes in the mouse embryonic germline in vivo.
Michael Sachs, Courtney Onodera, Kathryn Blaschke, Kevin T Ebata, Jun S Song

Cell Rep· June 2013

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Soluble growth factors stimulate spermatogonial stem cell divisions that maintain a stem cell pool and produce progenitors in vitro.
Kevin T Ebata, Jonathan R Yeh, Xiangfan Zhang, Makoto C Nagano

Exp Cell Res· June 2011

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The application of biomarkers of spermatogonial stem cells for restoring male fertility.
Kevin T Ebata, Jonathan R Yeh, Xiangfan Zhang, Makoto C Nagano

Dis Markers· August 2008

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Male germ line stem cells have an altered potential to proliferate and differentiate during postnatal development in mice.
Kevin T Ebata, Xiangfan Zhang, Makoto C Nagano

Biol Reprod· May 2007

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Aging of male germ line stem cells in mice.
Xiangfan Zhang, Kevin T Ebata, Bernard Robaire, Makoto C Nagano

Biol Reprod· January 2006

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